Dissection of contributions from invariant amino acids to complex formation and catalysis in the heteromeric pyridoxal 5-phosphate synthase complex from Bacillus subtilis

Pyridoxal 5-phosphate (PLP), an active form of vitamin B(6), is one of the most versatile cofactors and is involved in numerous biochemical reactions. The main pathway for de novo PLP biosynthesis leads to direct formation of PLP from a pentose and triose. This reaction is catalyzed by the heteromer...

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Bibliographic Details
Main Authors: Wallner, Silvia (Author), Neuwirth, Martina (Author), Flicker, Karlheinz (Author), Tews, Ivo (Author), Macheroux, Peter (Author)
Format: Article
Language:English
Published: 2009-03-10.
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