Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA
The loading of newly synthesised MHC class I molecules (MHCI) with peptides requires the involvement of several endoplasmic reticulum (ER)-resident cofactors including calnexin, calreticulin, transporter associated with antigen processing, ERp57 and tapasin. In the absence of tapasin, MHC I complexe...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
2004-03.
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| Subjects: | |
| Online Access: | Get fulltext Get fulltext |