nonhuman Article 1,198 controlled study 1,068 human 805 male 659 animal experiment 647 article 576 Animals 544 animal 510 Humans 463 female 444 animal model 387 unclassified drug 385 mouse 380 animal tissue 345 adult 337 metabolism 296 rat 278 genetics 263 Male 252 animal cell 249 priority journal 201 Female 191 chemistry 191 physiology 182 Mice 171 drug effect 164 protein expression 164 in vitro study 163 gene expression 151