Pharmaco-transcriptomic correlation analysis reveals novel responsive signatures to HDAC inhibitors and identifies Dasatinib as a synergistic interactor in small-cell lung cancer

by Haitang Yang, MD-PhD, Beibei Sun, Ke Xu, Yunfei He, Tuo Zhang, Sean R R Hall, Swee T. Tan, Ralph A. Schmid, Ren-Wang Peng, Guohong Hu, Feng Yao, MD-PhD
Published 2021-07-01

Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers associated with HBsAg loss

by Shue Xiong, Dan Zhu, Boyun Liang, Mingyue Li, Wen Pan, Junyi He, Hua Wang, Kathrin Sutter, Ulf Dittmer, Mengji Lu, Di Liu, Dongliang Yang, Jia Liu, Xin Zheng
Published 2021-07-01

An ethically-motivated, Bayesian, adaptive design clinical trial bringing hope to women with menorrhagia…and warmth to statisticians’ hearts

by Chris R Palmer
Published 2021-07-01

Deciphering CT texture features of human visceral fat to evaluate metabolic disorders and surgery-induced weight loss effects

by Juan Shi, Guoqing Bao, Jie Hong, Simin Wang, Yufei Chen, Shaoqian Zhao, Aibo Gao, Ru Zhang, Jingfen Hu, Wenjie Yang, Fuhua Yan, Ankang Lyu, Ruixin Liu, Bin Cui, Yuhong Chen, Jiabin Jin, Baiyong Shen, Yifei Zhang, Weiqiong Gu, Dagan Feng, Weiqing Wang, Jiqiu Wang, Xiuying Wang, Guang Ning
Published 2021-07-01

Loss of TRIM21 alleviates cardiotoxicity by suppressing ferroptosis induced by the chemotherapeutic agent doxorubicin

by Kai Hou, Jianliang Shen, Junrong Yan, Chuannan Zhai, Jingxia Zhang, Ji-An Pan, Ye Zhang, Yaping Jiang, Yongbo Wang, Richard Z. Lin, Hongliang Cong, Shenglan Gao, Wei-Xing Zong
Published 2021-07-01

Magnetic resonance imaging radiomics predicts preoperative axillary lymph node metastasis to support surgical decisions and is associated with tumor microenvironment in invasive br...

by Yunfang Yu, Zifan He, Jie Ouyang, Yujie Tan, Yongjian Chen, Yang Gu, Luhui Mao, Wei Ren, Jue Wang, Lili Lin, Zhuo Wu, Jingwen Liu, Qiyun Ou, Qiugen Hu, Anlin Li, Kai Chen, Chenchen Li, Nian Lu, Xiaohong Li, Fengxi Su, Qiang Liu, Chuanmiao Xie, Herui Yao
Published 2021-07-01

Fibrotic lung disease: A molecular glimpse into severe Covid-19?

by Paolo Spagnolo, Justin M Oldham
Published 2021-07-01

Multimodal imaging as optical biopsy system for gastritis diagnosis in humans, and input of the mouse model

by Thomas Bazin, Alexandre Krebs, Aude Jobart-Malfait, Vania Camilo, Valérie Michel, Yannick Benezeth, Franck Marzani, Eliette Touati, Dominique Lamarque
Published 2021-07-01

Classification of cardioembolic stroke based on a deep neural network using chest radiographs

by Han-Gil Jeong, Beom Joon Kim, Tackeun Kim, Jihoon Kang, Jun Yup Kim, Joonghee Kim, Joon-Tae Kim, Jong-Moo Park, Jae Guk Kim, Jeong-Ho Hong, Kyung Bok Lee, Tai Hwan Park, Dae-Hyun Kim, Chang Wan Oh, Moon-Ku Han, Hee-Joon Bae
Published 2021-07-01

Proinflammatory oscillations over the menstrual cycle drives bystander CD4 T cell recruitment and SHIV susceptibility from vaginal challenge

by Alison Swaims-Kohlmeier, Anandi N. Sheth, Jed Brody, Felicia P. Hardnett, Sunita Sharma, Erin Wells Bonning, Igho Ofotokun, Ivana Massud, J.Gerardo García-Lerma
Published 2021-07-01

A mass spectrometry-based targeted assay for detection of SARS-CoV-2 antigen from clinical specimens

by Santosh Renuse, Patrick M. Vanderboom, Anthony D. Maus, Jennifer V. Kemp, Kari M. Gurtner, Anil K. Madugundu, Sandip Chavan, Jane A. Peterson, Benjamin J. Madden, Kiran K. Mangalaparthi, Dong-Gi Mun, Smrita Singh, Benjamin R. Kipp, Surendra Dasari, Ravinder J. Singh, Stefan K. Grebe, Akhilesh Pandey
Published 2021-07-01

Tempo-spatial regulation of the Wnt pathway by FAM13A modulates the stemness of alveolar epithelial progenitors

by Xin Lin, Yujun Li, Lu Gong, Jeong H. Yun, Shuang Xu, Yohannes Tesfaigzi, Dandi Qiao, Xiaobo Zhou
Published 2021-07-01

Taking the next-gen step: Comprehensive antimicrobial resistance detection from Burkholderia pseudomallei

by Danielle E. Madden, BSc (Hons), Jessica R. Webb, PhD, Eike J. Steinig, BSc (Hons), Bart J. Currie, FRACP, Erin P. Price, PhD, Derek S. Sarovich, PhD
Published 2021-01-01

Retraction notice to ‘The miR 495-UBE2C-ABCG2/ERCC1 axis reverses cisplatin resistance by downregulating drug resistance genes in cisplatin-resistant non-small cell lung cancer cel...

by Jiwei Guo, Dan Jin, Yan Wu, Lijuan Yang, Jing Du, Kaikai Gong, Weiwei Chen, Juanjuan Dai, Shuang Miao, Sichuan Xi
Published 2021-01-01

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes

by Tatiana M. Garcia-Bates, Mariana L. Palma, Renee R. Anderko, Denise C. Hsu, Jintanat Ananworanich, Bette T. Korber, Gaurav D. Gaiha, Nittaya Phanuphak, Rasmi Thomas, Sodsai Tovanabutra, Bruce D. Walker, John W. Mellors, Paolo A. Piazza, Eugene Kroon, Sharon A. Riddler, Nelson L. Michael, Charles R. Rinaldo, Robbie B. Mailliard
Published 2021-01-01

Longitudinal plasma protein profiling of newly diagnosed type 2 diabetes

by Anders Gummesson, Elias Björnson, Linn Fagerberg, Wen Zhong, Abdellah Tebani, Fredrik Edfors, Caroline Schmidt, Annika Lundqvist, Martin Adiels, Fredrik Bäckhed, Jochen M Schwenk, Per-Anders Jansson, Mathias Uhlén, Göran Bergström
Published 2021-01-01

NF-κB sub-pathways and HIV cure: A revisit

by Lilly M. Wong, Guochun Jiang
Published 2021-01-01

Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling

by Katarina Lopusna, Pawel Nowialis, Jana Opavska, Ajay Abraham, Alberto Riva, Rene Opavsky
Published 2021-01-01

A novel imaging based Nomogram for predicting post-surgical biochemical recurrence and adverse pathology of prostate cancer from pre-operative bi-parametric MRI

by Lin Li, Rakesh Shiradkar, Patrick Leo, Ahmad Algohary, Pingfu Fu, Sree Harsha Tirumani, Amr Mahran, Christina Buzzy, Verena C Obmann, Bahar Mansoori, Ayah El-Fahmawi, Mohammed Shahait, Ashutosh Tewari, Cristina Magi-Galluzzi, David Lee, Priti Lal, Lee Ponsky, Eric Klein, Andrei S. Purysko, Anant Madabhushi
Published 2021-01-01

A breath of fresh air – the potential for COVID-19 breath diagnostics

by Cristina E. Davis, Michael Schivo, Nicholas J. Kenyon
Published 2021-01-01