Systems biology approaches to investigating the roles of extracellular vesicles in human diseases

by András Gézsi, Árpád Kovács, Tamás Visnovitz, Edit I. Buzás
Published 2019-03-01

Blocking TBK1 alleviated radiation-induced pulmonary fibrosis and epithelial-mesenchymal transition through Akt-Erk inactivation

by Hongjin Qu, Lei Liu, Zhe Liu, Hongran Qin, Zebin Liao, Penglin Xia, Yanyong Yang, Bailong Li, Fu Gao, Jianming Cai
Published 2019-04-01

Hypoxia signaling in human diseases and therapeutic targets

by Jae W. Lee, Junsuk Ko, Cynthia Ju, Holger K. Eltzschig
Published 2019-06-01

C-type natriuretic peptide attenuates renal osteodystrophy through inhibition of FGF-23/MAPK signaling

by Dong Dong Zhang, Yang Fang Wu, Wei Xia Chen, Yao Xu, Si Yan Liu, Huang Huang Luo, Guang Mei Jiang, Yue Wu, Peng Hu
Published 2019-07-01

Monitoring circulating tumor DNA by analyzing personalized cancer-specific rearrangements to detect recurrence in gastric cancer

by Young-Woo Kim, Young-Ho Kim, Yura Song, Han-Seong Kim, Hye Won Sim, Shiv Poojan, Bang Wool Eom, Myeong-Cherl Kook, Jungnam Joo, Kyeong-Man Hong
Published 2019-08-01

Hypermethylation of Frizzled1 is associated with Wnt/β-catenin signaling inactivation in mesenchymal stem cells of patients with steroid-associated osteonecrosis

by Fei Wu, Jing Jiao, Feng Liu, Yue Yang, Shanfeng Zhang, Zhenhua Fang, Zhipeng Dai, Zhibo Sun
Published 2019-02-01

Restoration of FVIII expression by targeted gene insertion in the FVIII locus in hemophilia A patient-derived iPSCs

by Jin Jea Sung, Chul-Yong Park, Joong Woo Leem, Myung Soo Cho, Dong-Wook Kim
Published 2019-04-01

Disturbed homocysteine metabolism is associated with cancer

by Tauheed Hasan, Reetika Arora, Aniket Kumar Bansal, Reshmee Bhattacharya, Gurumayum Suraj Sharma, Laishram Rajendrakumar Singh
Published 2019-02-01

Estrogen receptor α in T cells suppresses follicular helper T cell responses and prevents autoimmunity

by Do-Hyun Kim, Hong-Jai Park, Hyeon-Soo Park, Jae-Ung Lee, CheMyong Ko, Myung Chan Gye, Je-Min Choi
Published 2019-04-01

A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice

by Hyuk-Kwon Kwon, Mahesh Chandra Patra, Hyeon-Jun Shin, Xiangai Gui, Asma Achek, Suresh Panneerselvam, Dong-Jin Kim, Suk-Jong Song, Riwon Hong, Kyoung Soo Kim, Yang Gyun Kim, Francis Y. Lee, Dae-Hyun Hahm, Sang Ho Lee, Sangdun Choi
Published 2019-04-01

Extracellular signal-regulated kinase 5 increases radioresistance of lung cancer cells by enhancing the DNA damage response

by Weiwei Jiang, Guanghui Jin, Fangfang Cai, Xiao Chen, Nini Cao, Xiangyu Zhang, Jia Liu, Fei Chen, Feng Wang, Wei Dong, Hongqin Zhuang, Zi-Chun Hua
Published 2019-02-01

Inhibition of RIPK1-dependent regulated acinar cell necrosis provides protection against acute pancreatitis via the RIPK1/NF-κB/AQP8 pathway

by Peng-yu Duan, Yuan Ma, Xi-na Li, Feng-zhi Qu, Liang Ji, Xiao-yu Guo, Wang-jun Zhang, Fan Xiao, Le Li, Ji-sheng Hu, Bei Sun, Gang Wang
Published 2019-08-01

Extracellular vesicles in onco-nephrology

by Chiara Gai, Margherita A. C. Pomatto, Cristina Grange, Maria Chiara Deregibus, Giovanni Camussi
Published 2019-03-01

Identification of HDAC9 as a viable therapeutic target for the treatment of gastric cancer

by Kai Xiong, Hejun Zhang, Yang Du, Jie Tian, Shigang Ding
Published 2019-08-01

Diagnosis of Alzheimer’s disease utilizing amyloid and tau as fluid biomarkers

by Jinny Claire Lee, Soo Jung Kim, Seungpyo Hong, YoungSoo Kim
Published 2019-05-01

SMURF1-mediated ubiquitination of ARHGAP26 promotes ovarian cancer cell invasion and migration

by Xuri Chen, Shaoyun Chen, Yao Li, Yanling Gao, Shuying Huang, Hongping Li, Yuanfang Zhu
Published 2019-04-01

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia–reperfusion injury

by Xiaozhong Zheng, Ailiang Zhang, Margaret Binnie, Kris McGuire, Scott P. Webster, Jeremy Hughes, Sarah E. M. Howie, Damian J. Mole
Published 2019-02-01

Luteolin promotes apoptotic cell death via upregulation of Nrf2 expression by DNA demethylase and the interaction of Nrf2 with p53 in human colon cancer cells

by Kyoung Ah Kang, Mei Jing Piao, Yu Jae Hyun, Ao Xuan Zhen, Suk Ju Cho, Mee Jung Ahn, Joo Mi Yi, Jin Won Hyun
Published 2019-04-01

Overexpression of Nanog in amniotic fluid–derived mesenchymal stem cells accelerates dermal papilla cell activity and promotes hair follicle regeneration

by Junghyun Park, Eun Kyoung Jun, Daryeon Son, Wonjun Hong, Jihoon Jang, Wonjin Yun, Byung Sun Yoon, Gwonhwa Song, In Yong Kim, Seungkwon You
Published 2019-07-01

CLOCK and BMAL1 stabilize and activate RHOA to promote F-actin formation in cancer cells

by Teng-jiao Ma, Zhi-wei Zhang, Yi-lu Lu, Ying-ying Zhang, Da-chang Tao, Yun-qiang Liu, Yong-xin Ma
Published 2018-10-01