The Hunger Games: Aggregatibacter actinomycetemcomitans Exploits Human Neutrophils As an Epinephrine Source for Survival

by Hazel Ozuna, Silvia M. Uriarte, Silvia M. Uriarte, Donald R. Demuth, Donald R. Demuth
Published 2021-08-01

DNA Damage Repair Profiles Alteration Characterize a Hepatocellular Carcinoma Subtype With Unique Molecular and Clinicopathologic Features

by Peng Lin, Rui-zhi Gao, Rong Wen, Yun He, Hong Yang
Published 2021-08-01

Editorial: Thymic Epithelial Cells: New Insights Into the Essential Driving Force of T-Cell Differentiation

by Marita Bosticardo, Izumi Ohigashi, Jennifer E. Cowan, Nuno L. Alves, Nuno L. Alves
Published 2021-08-01

Cellular and Molecular Effects of SARS-CoV-2 Linking Lung Infection to the Brain

by Linda Francistiová, Linda Francistiová, Adrián Klepe, Adrián Klepe, Adrián Klepe, Géza Curley, Géza Curley, Géza Curley, Károly Gulya, András Dinnyés, András Dinnyés, András Dinnyés, Kata Filkor, Kata Filkor, Kata Filkor
Published 2021-08-01

Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

by Martina Kunkl, Martina Kunkl, Carola Amormino, Carola Amormino, Silvana Caristi, Silvana Caristi, Valentina Tedeschi, Maria Teresa Fiorillo, Revital Levy, Andrey Popugailo, Raymond Kaempfer, Loretta Tuosto, Loretta Tuosto
Published 2021-08-01

Clinical Application of Metagenomic Next-Generation Sequencing for Suspected Infections in Patients With Primary Immunodeficiency Disease

by Wenjing Tang, Yu Zhang, Chong Luo, Lina Zhou, Lina Zhou, Lina Zhou, Lina Zhou, Zhiyong Zhang, Xuemei Tang, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao, Xiaodong Zhao, Yunfei An, Yunfei An, Yunfei An, Yunfei An, Yunfei An
Published 2021-08-01

Immune Infiltrating Cells-Derived Risk Signature Based on Large-scale Analysis Defines Immune Landscape and Predicts Immunotherapy Responses in Glioma Tumor Microenvironment

by Nan Zhang, Nan Zhang, Hao Zhang, Zeyu Wang, Ziyu Dai, Xun Zhang, Quan Cheng, Quan Cheng, Quan Cheng, Zhixiong Liu, Zhixiong Liu
Published 2021-08-01

Immune Checkpoints Expression in Chronic Lung Allograft Rejection

by Ilaria Righi, Valentina Vaira, Valentina Vaira, Letizia Corinna Morlacchi, Giorgio Alberto Croci, Giorgio Alberto Croci, Valeria Rossetti, Francesco Blasi, Francesco Blasi, Stefano Ferrero, Stefano Ferrero, Mario Nosotti, Mario Nosotti, Lorenzo Rosso, Lorenzo Rosso, Mario Clerici, Mario Clerici
Published 2021-08-01

Microglia/Macrophages and CD4+CD25+ T Cells Enhance the Ability of Injury-Activated Lymphocytes to Reduce Traumatic Optic Neuropathy In Vitro

by Yiqun Geng, Yiqun Geng, Zhihao Lu, Jitian Guan, Nico van Rooijen, Ye Zhi
Published 2021-08-01

A Robust Hypoxia Risk Score Predicts the Clinical Outcomes and Tumor Microenvironment Immune Characters in Bladder Cancer

by Zhi Liu, Zhi Liu, Qiao Tang, Tiezheng Qi, Belaydi Othmane, Zhe Yang, Jinbo Chen, Jiao Hu, Xiongbing Zu
Published 2021-08-01

The Pathogenesis of Eosinophilic Asthma: A Positive Feedback Mechanism That Promotes Th2 Immune Response via Filaggrin Deficiency

by Wei Gao, Jiuyu Gong, Mi Mu, Yujin Zhu, Yujin Zhu, Wenjuan Wang, Wen Chen, Guojing Han, Hong Hu, Pengtao Bao
Published 2021-08-01

Unravelling the Shared Genetic Mechanisms Underlying 18 Autoimmune Diseases Using a Systems Approach

by Sreemol Gokuladhas, William Schierding, William Schierding, Evgeniia Golovina, Tayaza Fadason, Tayaza Fadason, Justin O’Sullivan, Justin O’Sullivan, Justin O’Sullivan, Justin O’Sullivan
Published 2021-08-01

Strategies for Accurate Cell Type Identification in CODEX Multiplexed Imaging Data

by John W. Hickey, John W. Hickey, Yuqi Tan, Yuqi Tan, Garry P. Nolan, Garry P. Nolan, Yury Goltsev, Yury Goltsev
Published 2021-08-01

Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease

by He Li, Yuehan Gao, Lihui Xie, Rong Wang, Runping Duan, Zhaohuai Li, Binyao Chen, Lei Zhu, Xianggui Wang, Xianggui Wang, Wenru Su
Published 2021-08-01

Design of a Novel Multi-Epitope Vaccine Against Echinococcus granulosus in Immunoinformatics

by Mingkai Yu, Yuejie Zhu, Yujiao Li, Zhiqiang Chen, Tong Sha, Zhiwei Li, Fengbo Zhang, Fengbo Zhang, Jianbing Ding, Jianbing Ding
Published 2021-08-01

ImmuCellDB: An Indicative Database of Immune Cell Composition From Different Tissues and Disease Conditions in Mouse and Human

by Ziyi Chen, Ziyi Chen, Ziyi Chen, Han Na, Han Na, Aiping Wu, Aiping Wu
Published 2021-08-01

Case Report: Convalescent Plasma Therapy Induced Anti-SARS-CoV-2 T Cell Expansion, NK Cell Maturation and Virus Clearance in a B Cell Deficient Patient After CD19 CAR T Cell Therap...

by Berislav Bošnjak, Ivan Odak, Christiane Ritter, Klaus Stahl, Theresa Graalmann, Theresa Graalmann, Lars Steinbrück, Rainer Blasczyk, Christine S. Falk, Christine S. Falk, Thomas F. Schulz, Thomas F. Schulz, Thomas F. Schulz, Hans Heinrich Wedemeyer, Hans Heinrich Wedemeyer, Hans Heinrich Wedemeyer, Markus Cornberg, Markus Cornberg, Markus Cornberg, Arnold Ganser, Reinhold Förster, Reinhold Förster, Christian Koenecke, Christian Koenecke, Christian Koenecke
Published 2021-08-01

Mouse Models of Germinal Center Derived B-Cell Lymphomas

by Stefanie N. Meyer, Sanjay Koul, Laura Pasqualucci, Laura Pasqualucci, Laura Pasqualucci
Published 2021-08-01

Neutrophil Extracellular Traps Exacerbate Secondary Injury via Promoting Neuroinflammation and Blood–Spinal Cord Barrier Disruption in Spinal Cord Injury

by Zhou Feng, Lingxia Min, Liang Liang, Beike Chen, Hui Chen, Yi Zhou, Weiwei Deng, Hongliang Liu, Jingming Hou
Published 2021-08-01

Interferon-Induced Transmembrane Protein 3 Shapes an Inflamed Tumor Microenvironment and Identifies Immuno-Hot Tumors

by Yun Cai, Wenfei Ji, Chuan Sun, Rui Xu, Xuechun Chen, Yifan Deng, Jiadong Pan, Jiayue Yang, Hongjun Zhu, Jie Mei, Jie Mei
Published 2021-08-01