Venous access devices for the delivery of long-term chemotherapy: the CAVA three-arm RCT

by Olivia Wu, Elaine McCartney, Robert Heggie, Evi Germeni, James Paul, Eileen Soulis, Susan Dillon, Caoimhe Ryan, Moira Sim, Judith Dixon-Hughes, Roshan Agarwal, Andrew Bodenham, Tobias Menne, Brian Jones, Jonathan Moss
Published 2021-07-01

Practice nurse-supported weight self-management delivered within the national child immunisation programme for postnatal women: a feasibility cluster RCT

by Amanda J Daley, Kate Jolly, Natalie Ives, Susan A Jebb, Sarah Tearne, Sheila M Greenfield, Lucy Yardley, Paul Little, Natalie Tyldesley-Marshall, Hannah Bensoussane, Ruth V Pritchett, Emma Frew, Helen M Parretti
Published 2021-08-01

Progressive exercise compared with best-practice advice, with or without corticosteroid injection, for rotator cuff disorders: the GRASP factorial RCT

by Sally Hopewell, David J Keene, Peter Heine, Ioana R Marian, Melina Dritsaki, Lucy Cureton, Susan J Dutton, Helen Dakin, Andrew Carr, Willie Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Karen Barker, Alastair Gray, Sarah E Lamb
Published 2021-08-01

Home environmental assessments and modification delivered by occupational therapists to reduce falls in people aged 65 years and over: the OTIS RCT

by Sarah Cockayne, Alison Pighills, Joy Adamson, Caroline Fairhurst, Shelley Crossland, Avril Drummond, Catherine E Hewitt, Sara Rodgers, Sarah J Ronaldson, Jennifer McCaffery, Katie Whiteside, Arabella Scantlebury, Lyn Robinson-Smith, Ann Cochrane, Sarah E Lamb, Sophie Boyes, Simon Gilbody, Clare Relton, David J Torgerson
Published 2021-07-01

The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT

by Jane E Norman, John Norrie, Graeme MacLennan, David Cooper, Sonia Whyte, Sushila Chowdhry, Sarah Cunningham-Burley, Aileen R Neilson, Xue W Mei, Joel BE Smith, Andrew Shennan, Stephen C Robson, Steven Thornton, Mark D Kilby, Neil Marlow, Sarah J Stock, Philip R Bennett, Jane Denton
Published 2021-07-01

Prognostic biomarkers to identify patients likely to develop severe Crohn’s disease: a systematic review

by Steve Halligan, Darren Boone, Lucinda Archer, Tariq Ahmad, Stuart Bloom, Manuel Rodriguez-Justo, Stuart A Taylor, Sue Mallett
Published 2021-07-01

Provision of the progestogen-only pill by community pharmacies as bridging contraception for women receiving emergency contraception: the Bridge-it RCT

by Sharon T Cameron, Anna Glasier, Lisa McDaid, Andrew Radley, Susan Patterson, Paula Baraitser, Judith Stephenson, Richard Gilson, Claire Battison, Kathleen Cowle, Thenmalar Vadiveloo, Anne Johnstone, Alessandra Morelli, Beatriz Goulao, Mark Forrest, Alison McDonald, John Norrie
Published 2021-05-01

Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation

by Irina A Tikhonova, Huiqin Yang, Segun Bello, Andrew Salmon, Sophie Robinson, Mohsen Rezaei Hemami, Sophie Dodman, Andriy Kharechko, Richard C Haigh, Meghna Jani, Timothy J McDonald, Martin Hoyle
Published 2021-02-01

Psychological intervention, antipsychotic medication or a combined treatment for adolescents with a first episode of psychosis: the MAPS feasibility three-arm RCT

by Anthony P Morrison, Melissa Pyle, Rory Byrne, Matthew Broome, Daniel Freeman, Louise Johns, Anthony James, Nusrat Husain, Richard Whale, Graeme MacLennan, John Norrie, Jemma Hudson, Sarah Peters, Linda Davies, Samantha Bowe, Jo Smith, David Shiers, Emmeline Joyce, Wendy Jones, Chris Hollis, Daniel Maughan
Published 2021-01-01

Lansoprazole for persistent throat symptoms in secondary care: the TOPPITS RCT

by Janet A Wilson, Deborah D Stocken, Gillian C Watson, Tony Fouweather, Julian McGlashan, Kenneth MacKenzie, Paul Carding, Yakubu Karagama, Meredydd Harries, Stephen Ball, Sadie Khwaja, Declan Costello, Ruth Wood, Jan Lecouturier, James O’Hara
Published 2021-01-01

Individualised placement and support programme for people unemployed because of chronic pain: a feasibility study and the InSTEP pilot RCT

by Cathy Linaker, Simon Fraser, Cathy Price, Nick Maguire, Paul Little, Ira Madan, Rafael Pinedo-Villanueva, David Coggon, Cyrus Cooper, Georgia Ntani, Karen Walker-Bone
Published 2021-01-01

Femtosecond laser-assisted cataract surgery compared with phacoemulsification: the FACT non-inferiority RCT

by Alexander C Day, Jennifer M Burr, Kate Bennett, Rachael Hunter, Catey Bunce, Caroline J Doré, Mayank A Nanavaty, Kamaljit S Balaggan, Mark R Wilkins
Published 2021-01-01

Prehospital continuous positive airway pressure for acute respiratory failure: the ACUTE feasibility RCT

by Gordon W Fuller, Samuel Keating, Steve Goodacre, Esther Herbert, Gavin D Perkins, Andy Rosser, Imogen Gunson, Joshua Miller, Matthew Ward, Mike Bradburn, Praveen Thokala, Tim Harris, Margaret M Marsh, Alexander J Scott, Cindy Cooper
Published 2021-02-01

Patch augmentation surgery for rotator cuff repair: the PARCS mixed-methods feasibility study

by Jonathan A Cook, Mathew Baldwin, Cushla Cooper, Navraj S Nagra, Joanna C Crocker, Molly Glaze, Gemma Greenall, Amar Rangan, Lucksy Kottam, Jonathan L Rees, Dair Farrar-Hockley, Naomi Merritt, Sally Hopewell, David Beard, Michael Thomas, Melina Dritsaki, Andrew J Carr
Published 2021-02-01

Reduced exposure to vasopressors through permissive hypotension to reduce mortality in critically ill people aged 65 and over: the 65 RCT

by Paul R Mouncey, Alvin Richards-Belle, Karen Thomas, David A Harrison, M Zia Sadique, Richard D Grieve, Julie Camsooksai, Robert Darnell, Anthony C Gordon, Doreen Henry, Nicholas Hudson, Alexina J Mason, Michelle Saull, Chris Whitman, J Duncan Young, François Lamontagne, Kathryn M Rowan, the 65 trial investigators
Published 2021-02-01

A case management occupational health model to facilitate earlier return to work of NHS staff with common mental health disorders: a feasibility study

by Vaughan Parsons, Dorota Juszczyk, Gill Gilworth, Georgia Ntani, Paul McCrone, Stephani Hatch, Robert Shannon, Max Henderson, David Coggon, Mariam Molokhia, Julia Smedley, Amanda Griffiths, Karen Walker-Bone, Ira Madan
Published 2021-02-01

Cognitive–behavioural therapy for a variety of conditions: an overview of systematic reviews and panoramic meta-analysis

by Beth Fordham, Thavapriya Sugavanam, Katherine Edwards, Karla Hemming, Jeremy Howick, Bethan Copsey, Hopin Lee, Milla Kaidesoja, Shona Kirtley, Sally Hopewell, Roshan das Nair, Robert Howard, Paul Stallard, Julia Hamer-Hunt, Zafra Cooper, Sarah E Lamb
Published 2021-02-01

Conservative treatment for uncomplicated appendicitis in children: the CONTRACT feasibility study, including feasibility RCT

by Nigel J Hall, Frances C Sherratt, Simon Eaton, Isabel Reading, Erin Walker, Maria Chorozoglou, Lucy Beasant, Wendy Wood, Michael Stanton, Harriet J Corbett, Dean Rex, Natalie Hutchings, Elizabeth Dixon, Simon Grist, William van’t Hoff, Esther Crawley, Jane Blazeby, Bridget Young
Published 2021-02-01

Preoperative intravenous iron for anaemia in elective major open abdominal surgery: the PREVENTT RCT

by Toby Richards, Ravishankar Rao Baikady, Ben Clevenger, Anna Butcher, Sandy Abeysiri, Marisa Chau, Rebecca Swinson, Tim Collier, Matthew Dodd, Laura Van Dyck, Iain Macdougall, Gavin Murphy, John Browne, Andrew Bradbury, Andrew Klein
Published 2021-02-01

Intratumoural immune signature to identify patients with primary colorectal cancer who do not require follow-up after resection: an observational study

by John N Primrose, Siân A Pugh, Gareth Thomas, Matthew Ellis, Karwan Moutasim, David Mant
Published 2021-01-01