Characterizing Emerging Canine H3 Influenza Viruses.

by Luis Martinez-Sobrido, Pilar Blanco-Lobo, Laura Rodriguez, Theresa Fitzgerald, Hanyuan Zhang, Phuong Nguyen, Christopher S Anderson, Jeanne Holden-Wiltse, Sanjukta Bandyopadhyay, Aitor Nogales, Marta L DeDiego, Brian R Wasik, Benjamin L Miller, Carole Henry, Patrick C Wilson, Mark Y Sangster, John J Treanor, David J Topham, Lauren Byrd-Leotis, David A Steinhauer, Richard D Cummings, Jasmina M Luczo, Stephen M Tompkins, Kaori Sakamoto, Cheryl A Jones, John Steel, Anice C Lowen, Shamika Danzy, Hui Tao, Ashley L Fink, Sabra L Klein, Nicholas Wohlgemuth, Katherine J Fenstermacher, Farah El Najjar, Andrew Pekosz, Lauren Sauer, Mitra K Lewis, Kathryn Shaw-Saliba, Richard E Rothman, Zhen-Ying Liu, Kuan-Fu Chen, Colin R Parrish, Ian E H Voorhees, Yoshihiro Kawaoka, Gabriele Neumann, Shiho Chiba, Shufang Fan, Masato Hatta, Huihui Kong, Gongxun Zhong, Guojun Wang, Melissa B Uccellini, Adolfo García-Sastre, Daniel R Perez, Lucas M Ferreri, Sander Herfst, Mathilde Richard, Ron Fouchier, David Burke, David Pattinson, Derek J Smith, Victoria Meliopoulos, Pamela Freiden, Brandi Livingston, Bridgett Sharp, Sean Cherry, Juan Carlos Dib, Guohua Yang, Charles J Russell, Subrata Barman, Richard J Webby, Scott Krauss, Angela Danner, Karlie Woodard, Malik Peiris, R A P M Perera, M C W Chan, Elena A Govorkova, Bindumadhav M Marathe, Philippe N Q Pascua, Gavin Smith, Yao-Tsun Li, Paul G Thomas, Stacey Schultz-Cherry
Published 2020-04-01

The influenza virus protein PB1-F2 inhibits the induction of type I interferon at the level of the MAVS adaptor protein.

by Zsuzsanna T Varga, Irene Ramos, Rong Hai, Mirco Schmolke, Adolfo García-Sastre, Ana Fernandez-Sesma, Peter Palese
Published 2011-06-01

Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.

by Dmitriy Zamarin, Adolfo García-Sastre, Xiaoyao Xiao, Rong Wang, Peter Palese
Published 2005-09-01

In vivo ligands of MDA5 and RIG-I in measles virus-infected cells.

by Simon Runge, Konstantin M J Sparrer, Charlotte Lässig, Katharina Hembach, Alina Baum, Adolfo García-Sastre, Johannes Söding, Karl-Klaus Conzelmann, Karl-Peter Hopfner
Published 2014-04-01

The ETS transcription factor ELF1 regulates a broadly antiviral program distinct from the type I interferon response.

by Leon Louis Seifert, Clara Si, Debjani Saha, Mohammad Sadic, Maren de Vries, Sarah Ballentine, Aaron Briley, Guojun Wang, Ana M Valero-Jimenez, Adil Mohamed, Uwe Schaefer, Hong M Moulton, Adolfo García-Sastre, Shashank Tripathi, Brad R Rosenberg, Meike Dittmann
Published 2019-11-01

Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response.

by Niyas Kudukkil Pulloor, Sajith Nair, Kathleen McCaffrey, Aleksandar D Kostic, Pradeep Bist, Jeremy D Weaver, Andrew M Riley, Richa Tyagi, Pradeep D Uchil, John D York, Solomon H Snyder, Adolfo García-Sastre, Barry V L Potter, Rongtuan Lin, Stephen B Shears, Ramnik J Xavier, Manoj N Krishnan
Published 2014-02-01

Chemical intervention of influenza virus mRNA nuclear export.

by Matthew Esparza, Amir Mor, Hanspeter Niederstrasser, Kris White, Alexander White, Ke Zhang, Shengyan Gao, Juan Wang, Jue Liang, Sei Sho, Ramanavelan Sakthivel, Adwait A Sathe, Chao Xing, Raquel Muñoz-Moreno, Jerry W Shay, Adolfo García-Sastre, Joseph Ready, Bruce Posner, Beatriz M A Fontoura
Published 2020-04-01

Dengue virus co-opts UBR4 to degrade STAT2 and antagonize type I interferon signaling.

by Juliet Morrison, Maudry Laurent-Rolle, Ana M Maestre, Ricardo Rajsbaum, Giuseppe Pisanelli, Viviana Simon, Lubbertus C F Mulder, Ana Fernandez-Sesma, Adolfo García-Sastre
Published 2013-03-01

Species-specific inhibition of RIG-I ubiquitination and IFN induction by the influenza A virus NS1 protein.

by Ricardo Rajsbaum, Randy A Albrecht, May K Wang, Natalya P Maharaj, Gijs A Versteeg, Estanislao Nistal-Villán, Adolfo García-Sastre, Michaela U Gack
Published 2012-01-01

Protection of mice against lethal challenge with 2009 H1N1 influenza A virus by 1918-like and classical swine H1N1 based vaccines.

by Balaji Manicassamy, Rafael A Medina, Rong Hai, Tshidi Tsibane, Silke Stertz, Estanislao Nistal-Villán, Peter Palese, Christopher F Basler, Adolfo García-Sastre
Published 2010-01-01

A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses.

by Shashank Tripathi, Vinod R M T Balasubramaniam, Julia A Brown, Ignacio Mena, Alesha Grant, Susana V Bardina, Kevin Maringer, Megan C Schwarz, Ana M Maestre, Marion Sourisseau, Randy A Albrecht, Florian Krammer, Matthew J Evans, Ana Fernandez-Sesma, Jean K Lim, Adolfo García-Sastre
Published 2017-03-01

Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway.

by Erik de Vries, Donna M Tscherne, Marleen J Wienholts, Viviana Cobos-Jiménez, Florine Scholte, Adolfo García-Sastre, Peter J M Rottier, Cornelis A M de Haan
Published 2011-03-01

Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.

by Sharon K Kuss-Duerkop, Juan Wang, Ignacio Mena, Kris White, Giorgi Metreveli, Ramanavelan Sakthivel, Miguel A Mata, Raquel Muñoz-Moreno, Xiang Chen, Florian Krammer, Michael S Diamond, Zhijian J Chen, Adolfo García-Sastre, Beatriz M A Fontoura
Published 2017-09-01

H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice.

by Lucy A Perrone, Julie K Plowden, Adolfo García-Sastre, Jacqueline M Katz, Terrence M Tumpey
Published 2008-08-01

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection.

by Emilio Yángüez, Alicia García-Culebras, Aldo Frau, Catalina Llompart, Klaus-Peter Knobeloch, Sylvia Gutierrez-Erlandsson, Adolfo García-Sastre, Mariano Esteban, Amelia Nieto, Susana Guerra
Published 2013-10-01

Correction: ISG15 Regulates Peritoneal Macrophages Functionality against Viral Infection.

by Emilio Yángüez, Alicia García-Culebras, Aldo Frau, Catalina Llompart, Klaus-Peter Knobeloch, Sylvia Gutierrez-Erlandsson, Adolfo García-Sastre, Mariano Esteban, Amelia Nieto, Susana Guerra
Published 2016-10-01

Influenza B virus ribonucleoprotein is a potent activator of the antiviral kinase PKR.

by Bianca Dauber, Luis Martínez-Sobrido, Jana Schneider, Rong Hai, Zoe Waibler, Ulrich Kalinke, Adolfo García-Sastre, Thorsten Wolff
Published 2009-06-01

Differential contribution of PB1-F2 to the virulence of highly pathogenic H5N1 influenza A virus in mammalian and avian species.

by Mirco Schmolke, Balaji Manicassamy, Lindomar Pena, Troy Sutton, Rong Hai, Zsuzsanna T Varga, Benjamin G Hale, John Steel, Daniel R Pérez, Adolfo García-Sastre
Published 2011-08-01

Expected and Unexpected Features of the Newly Discovered Bat Influenza A-like Viruses.

by Wenjun Ma, Adolfo García-Sastre, Martin Schwemmle
Published 2015-06-01

ISG15 regulates peritoneal macrophages functionality against viral infection.

by Emilio Yángüez, Alicia García-Culebras, Aldo Frau, Catalina Llompart, Klaus-Peter Knobeloch, Sylvia Gutierrez-Erlandsson, Adolfo García-Sastre, Mariano Esteban, Amelia Nieto, Susana Guerra
Published 2013-01-01