human 200 single nucleotide polymorphism 191 Humans 152 genetics 128 Article 121 Polymorphism, Single Nucleotide 120 female 103 controlled study 94 male 94 adult 93 genotype 89 Female 68 Male 63 major clinical study 60 genome-wide association study 58 genetic association 57 gene frequency 55 Genetic Predisposition to Disease 48 genetic predisposition 48 genetic variability 47 Adult 46 middle aged 46 Genome-Wide Association Study 45 allele 41 Middle Aged 39 phenotype 38 case control study 37 article 36 Genotype 34 gene 34