Computer aided molecular design 1 Computer-aided molecular design 1 Eye cream 1 Health 1 Health indices 1 Margin of exposure 1 Margins of exposures 1 Optimisations 1 Optimization Personal care product preservative 1 Personal care products 1 Personal care products preservative 1 Product design 1 Quality safety 1 Safety and health index 1 Safety and healths 1 Safety indexes 1