Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome

by Sam A. Booker, Laura Simões de Oliveira, Natasha J. Anstey, Zrinko Kozic, Owen R. Dando, Adam D. Jackson, Paul S. Baxter, Lori L. Isom, Diane L. Sherman, Giles E. Hardingham, Peter J. Brophy, David J.A. Wyllie, Peter C. Kind
Published 2020-08-01

Paracrine cellular senescence exacerbates biliary injury and impairs regeneration

by Sofia Ferreira-Gonzalez, Wei-Yu Lu, Alexander Raven, Benjamin Dwyer, Tak Yung Man, Eoghan O’Duibhir, Philip J. Starkey Lewis, Lara Campana, Tim J. Kendall, Thomas G. Bird, Nuria Tarrats, Juan-Carlos Acosta, Luke Boulter, Stuart J. Forbes
Published 2018-03-01

Role of Tim4 in the regulation of ABCA1+ adipose tissue macrophages and post-prandial cholesterol levels

by M. S. Magalhaes, P. Smith, J. R. Portman, L. H. Jackson-Jones, C. C. Bain, P. Ramachandran, Z. Michalidou, R. H. Stimson, M. R. Dweck, L. Denby, N. C. Henderson, S. J. Jenkins, C. Bénézech
Published 2021-07-01

An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein

by Pooran Singh Dewari, Benjamin Southgate, Katrina Mccarten, German Monogarov, Eoghan O'Duibhir, Niall Quinn, Ashley Tyrer, Marie-Christin Leitner, Colin Plumb, Maria Kalantzaki, Carla Blin, Rebecca Finch, Raul Bardini Bressan, Gillian Morrison, Ashley M Jacobi, Mark A Behlke, Alex von Kriegsheim, Simon Tomlinson, Jeroen Krijgsveld, Steven M Pollard
Published 2018-04-01

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

by Rocío Rojo, Anna Raper, Derya D. Ozdemir, Lucas Lefevre, Kathleen Grabert, Evi Wollscheid-Lengeling, Barry Bradford, Melanie Caruso, Iveta Gazova, Alejandra Sánchez, Zofia M. Lisowski, Joana Alves, Irene Molina-Gonzalez, Hayk Davtyan, Rebecca J. Lodge, James D. Glover, Robert Wallace, David A. D. Munro, Eyal David, Ido Amit, Véronique E. Miron, Josef Priller, Stephen J. Jenkins, Giles E. Hardingham, Mathew Blurton-Jones, Neil A. Mabbott, Kim M. Summers, Peter Hohenstein, David A. Hume, Clare Pridans
Published 2019-07-01

Characterisation of an atherosclerotic micro-calcification model using ApoE−/− mice and PET/CT

by Mark G. MacAskill, Wendy McDougald, Carlos Alcaide-Corral, David E. Newby, Adriana A.S. Tavares, Patrick W.F. Hadoke, Junxi Wu
Published 2020-12-01

De novo DNA methyltransferase activity in colorectal cancer is directed towards H3K36me3 marked CpG islands

by Roza H. Ali Masalmeh, Francesca Taglini, Cristina Rubio-Ramon, Kamila I. Musialik, Jonathan Higham, Hazel Davidson-Smith, Ioannis Kafetzopoulos, Kamila P. Pawlicka, Hannah M. Finan, Richard Clark, Jimi Wills, Andrew J. Finch, Lee Murphy, Duncan Sproul
Published 2021-01-01

Clinical effectiveness and service implications of telemonitoring for chronic obstructive pulmonary disease: the TELESCOT COPD randomised controlled trial

by Hilary Pinnock, Lucy McCloughan, Allison Todd, Janet Hanley, Stephanie Lewis, Ashma Krishan, William MacNee, Claudia Plagiari, Aziz Sheikh, Brian McKinstry
Published 2013-11-01

Dynamic control of proinflammatory cytokines Il-1β and Tnf-α by macrophages in zebrafish spinal cord regeneration

by Themistoklis M. Tsarouchas, Daniel Wehner, Leonardo Cavone, Tahimina Munir, Marcus Keatinge, Marvin Lambertus, Anna Underhill, Thomas Barrett, Elias Kassapis, Nikolay Ogryzko, Yi Feng, Tjakko J. van Ham, Thomas Becker, Catherina G. Becker
Published 2018-11-01

Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells

by Poulomi Banerjee, Evdokia Paza, Emma M. Perkins, Owen G. James, Boyd Kenkhuis, Amy F. Lloyd, Karen Burr, David Story, Dilmurat Yusuf, Xin He, Rolf Backofen, Owen Dando, Siddharthan Chandran, Josef Priller
Published 2020-12-01

Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

by Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C. Todd, Samuel Heron, Nóra M. Márkus, Jamie McQueen, David W. Hampton, Megan Torvell, Sachin S. Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J. A. Wyllie, T. Ian Simpson, Giles E. Hardingham
Published 2017-05-01

Author Correction: A unified resource and configurable model of the synapse proteome and its role in disease

by Oksana Sorokina, Colin Mclean, Mike D. R. Croning, Katharina F. Heil, Emilia Wysocka, Xin He, David Sterratt, Seth G. N. Grant, T. Ian Simpson, J. Douglas Armstrong
Published 2021-08-01

Clinical effectiveness and service implications of telemonitoring for chronic obstructive pulmonary disease: the TELESCOT COPD randomised controlled trial

by Hilary Pinnock, Lucy McCloughan, Allison Todd, Janet Hanley, Stephanie Lewis, Ashma Krishan, William MacNee, Claudia Plagiari, Aziz Sheikh, Brian McKinstry
Published 2013-11-01

40 Years of CSF Toxicity Studies in ALS: What Have We Learnt About ALS Pathophysiology?

by Koy Chong Ng Kee Kwong, Pratap K. Harbham, Bhuvaneish T. Selvaraj, Bhuvaneish T. Selvaraj, Bhuvaneish T. Selvaraj, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Jenna M. Gregory, Suvankar Pal, Suvankar Pal, Suvankar Pal, Giles E. Hardingham, Giles E. Hardingham, Giles E. Hardingham, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Siddharthan Chandran, Arpan R. Mehta, Arpan R. Mehta, Arpan R. Mehta, Arpan R. Mehta, Arpan R. Mehta
Published 2021-03-01

Author Correction: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

by David M. Howard, Mark J. Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E. Marioni, Gail Davies, Jonathan R. I. Coleman, Clara Alloza, Xueyi Shen, Miruna C. Barbu, Eleanor M. Wigmore, Jude Gibson, 23andMe Research Team, Saskia P. Hagenaars, Cathryn M. Lewis, Joey Ward, Daniel J. Smith, Patrick F. Sullivan, Chris S. Haley, Gerome Breen, Ian J. Deary, Andrew M. McIntosh
Published 2021-03-01

Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPDResearch in context

by Mairead L. Bermingham, Rosie M. Walker, Riccardo E. Marioni, Stewart W. Morris, Konrad Rawlik, Yanni Zeng, Archie Campbell, Paul Redmond, Heather C. Whalley, Mark J. Adams, Caroline Hayward, Ian J. Deary, David J. Porteous, Andrew M. McIntosh, Kathryn L. Evans
Published 2019-05-01

Bone marrow adipose tissue is a unique adipose subtype with distinct roles in glucose homeostasis

by Karla J. Suchacki, Adriana A. S. Tavares, Domenico Mattiucci, Erica L. Scheller, Giorgos Papanastasiou, Calum Gray, Matthew C. Sinton, Lynne E. Ramage, Wendy A. McDougald, Andrea Lovdel, Richard J. Sulston, Benjamin J. Thomas, Bonnie M. Nicholson, Amanda J. Drake, Carlos J. Alcaide-Corral, Diana Said, Antonella Poloni, Saverio Cinti, Gavin J. Macpherson, Marc R. Dweck, Jack P. M. Andrews, Michelle C. Williams, Robert J. Wallace, Edwin J. R. van Beek, Ormond A. MacDougald, Nicholas M. Morton, Roland H. Stimson, William P. Cawthorn
Published 2020-06-01

Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

by David M. Howard, Mark J. Adams, Masoud Shirali, Toni-Kim Clarke, Riccardo E. Marioni, Gail Davies, Jonathan R. I. Coleman, Clara Alloza, Xueyi Shen, Miruna C. Barbu, Eleanor M. Wigmore, Jude Gibson, Saskia P. Hagenaars, Cathryn M. Lewis, Joey Ward, Daniel J. Smith, Patrick F. Sullivan, Chris S. Haley, Gerome Breen, Ian J. Deary, Andrew M. McIntosh
Published 2018-08-01

Activated neutrophil fluorescent imaging technique for human lungs

by Thomas H. Craven, Tashfeen Walton, Ahsan R. Akram, Emma Scholefield, Neil McDonald, Adam D.L. Marshall, Duncan C. Humphries, Bethany Mills, Thane A. Campbell, Annya Bruce, Joanne Mair, James W. Dear, David E. Newby, Adam T. Hill, Timothy S. Walsh, Chris Haslett, Kevin Dhaliwal
Published 2021-01-01

Quantitative measurements of enlarged perivascular spaces in the brain are associated with retinal microvascular parameters in older community-dwelling subjects

by Lucia Ballerini, Sarah McGrory, Maria del C. Valdés Hernández, Ruggiero Lovreglio, Enrico Pellegrini, Tom MacGillivray, Susana Muñoz Maniega, Ross Henderson, Adele Taylor, Mark E. Bastin, Fergus Doubal, Emanuele Trucco, Ian J. Deary, Joanna Wardlaw
Published 2020-01-01