Showing 1 - 16 results of 16 for search 'CANCER CHEMOTHERAPEUTICS', query time: 1.56s Refine Results
  1. 1
    Chk1 Inhibitor MK-8776 Restores the Sensitivity of Chemotherapeutics in P-glycoprotein Overexpressing Cancer Cells
    “...), which results in the failure of cancer treatment. Here, we report that checkpoint kinase (Chk) 1...”
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    Article
  2. 2
    The Novel benzamide Derivative, VKNG-2, Restores the Efficacy of Chemotherapeutic Drugs in Colon Cancer Cell Lines by Inhibiting the ABCG2 Transporter
    “... multidrug resistance (MDR) in certain types of cancer cells. ABCG2-mediated MDR can significantly attenuate...”
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    Article
  3. 3
    Venetoclax, a BCL-2 Inhibitor, Enhances the Efficacy of Chemotherapeutic Agents in Wild-Type ABCG2-Overexpression-Mediated MDR Cancer Cells
    “...Cancers...”
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    Article
  4. 4
    Antimicrobial Peptide Reverses ABCB1-Mediated Chemotherapeutic Drug Resistance
    “...Multidrug resistance (MDR) of tumor cells to chemotherapeutic agents is the main reason...”
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  5. 5
    Erdafitinib Antagonizes ABCB1-Mediated Multidrug Resistance in Cancer Cells
    Subjects: “...cancer...”
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  6. 6
    Reversal Effect of ALK Inhibitor NVP-TAE684 on ABCG2-Overexpressing Cancer Cells
    “...Failure of cancer chemotherapy is mostly due to multidrug resistance (MDR). Overcoming MDR mediated...”
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    Article
  7. 7
    Overexpression of ABCB1 Transporter Confers Resistance to mTOR Inhibitor WYE-354 in Cancer Cells
    “... the effect of WYE-354 on the cellular accumulation of chemotherapeutic drugs. The ATPase (adenosine...”
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    Article
  8. 8
    Establishment and Characterization of a Novel Multidrug Resistant Human Ovarian Cancer Cell Line With Heterogenous MRP7 Overexpression
    Subjects: “...ovarian cancer...”
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    Article
  9. 9
    Bruton’s Tyrosine Kinase (BTK) Inhibitor RN486 Overcomes ABCB1-Mediated Multidrug Resistance in Cancer Cells
    “... of chemotherapeutic drugs that are substrates of ABCB1 transporter in ABCB1-overexpression cancer cells and reverse...”
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    Article
  10. 10
    Establishment and Characterization of a Topotecan Resistant Non-small Cell Lung Cancer NCI-H460/TPT10 Cell Line
    Subjects: “...non-small cell lung cancer...”
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    Article
  11. 11
    VKNG-1 Antagonizes ABCG2-Mediated Multidrug Resistance via p-AKT and Bcl-2 Pathway in Colon Cancer: In Vitro and In Vivo Study
    “...Cancers...”
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    Article
  12. 12
    Poziotinib Inhibits the Efflux Activity of the ABCB1 and ABCG2 Transporters and the Expression of the ABCG2 Transporter Protein in Multidrug Resistant Colon Cancer Cells
    Subjects: “...colorectal cancer...”
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    Article
  13. 13
    Reversal of Cancer Multidrug Resistance (MDR) Mediated by ATP-Binding Cassette Transporter G2 (ABCG2) by AZ-628, a RAF Kinase Inhibitor
    “...Overexpression of ABCG2 remains a major impediment to successful cancer treatment, because ABCG2...”
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    Article
  14. 14
    Olmutinib (BI1482694/HM61713), a Novel Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitor, Reverses ABCG2-Mediated Multidrug Resistance in Cancer Cells
    Subjects: “...breast cancer resistance protein (BCRP/ABCG2)...”
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    Article
  15. 15
    Midostaurin Reverses ABCB1-Mediated Multidrug Resistance, an in vitro Study
    “...Overexpression of ABC transporters in cancer cells is an underlying mechanism of multidrug...”
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    Article
  16. 16
    NVP-CGM097, an HDM2 Inhibitor, Antagonizes ATP-Binding Cassette Subfamily B Member 1-Mediated Drug Resistance
    “...Multidrug resistance (MDR) is a major challenge in the treatment of tumors. It refers to cancer...”
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    Article
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