Genome-wide association study and functional validation implicates JADE1 in tauopathy

by Andrews, S.J, Attems, J., Ayalon, G., Beach, T.G, Bhangale, T., Borukov, V.Y, Bowles, K.R, Cairns, N.J, Casella, A., Cherry, J.D, Cobos, I., Cohen, H.T, Corrada, M.M, Cortes, E.P, Crary, J.F, Dangoor, D.K, de Paiva Lopes, K., Dickson, D.W, Farrell, K., Fischer, P., Flanagan, M.E, Franklin, E.E, Frosch, M.P, Frost, B., Fulton-Howard, B., Gandy, S., Gearing, M., Glass, J., Goate, A., Gonzalez, E.M, Graham, R.R, Han, N., Haroutunian, V., Hefti, M.M, Hof, P.R, Humphrey, J., Hunkapiller, J., Hyman, B.T, Iida, M.A, Kapoor, M., Kawas, C.H, Keene, C.D, Kim, S.H, Kofler, J., Kovacs, G.G, Latimer, C.S, Lee, E.B, Lutz, M.I, Mao, Q., Marcora, E., McKee, A.C, McMillan, C.T, Mesulam, M.-M, Metcalf, J., Montine, T.J, Murray, M.E, Nelson, P.T, Novikova, G., Otero-Garcia, M., Perrin, R.J, Pham, T., Poon, W., Purohit, D.P, Raj, T., Renton, A.E, Richardson, T.E, Rissman, R.A, Salehi, B., Sano, M., Schneider, J.A, Shuldberg, S., Sissoko, C.T, Stein, T.D, Tang, W., Teich, A.F, Trojanowski, J.Q, Troncoso, J.C, Udine, E., Vialle, R.A, Vonsattel, J.-P, Walker, J.M, Walsh, H., Weintraub, S., White III, C.L, Whitney, K., Wolk, D.A, Woltjer, R.L, Wong, G., Yu, L.
Published 2022

Insight of the mitochondrial genomes of the Orang Asli and Malays: The heterogeneity and the disease-associated variants

by Noorizhab, M.N.F, Salleh, M.Z, Sukri, A., Teh, L.K
Published 2022

Systematic Pharmacogenomics Analysis of a Malay Whole Genome: Proof of Concept for Personalized Medicine

by Adam, A., Ahmed, A.Z, Hamzah, A.S, Hatta, F.H.M, Hoh, B.P, Ismail, M.I, Ismet, R.I, Janor, R.M, Joshi, K., Lee, L.S, Pasha, A., Patowary, A., Salleh, M.Z, Scaria, V., Sivasubbu, S., Teh, L.K, Yusoff, K.

A genome-wide characterization of copy number variations in native populations of Peninsular Malaysia

by Fu, R., Hoh, B.-P, Mokhtar, S.S, Phipps, M.E, Xu, S.
Published 2018

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1

by Bye, C.R, Cheng, F.-F, Garton, F.C, Giacomotto, J., Gusev, A., Henders, A.K, Henderson, R.D, Kabashi, E., Kiernan, M.C, Mathers, S., McCombe, P.A, McRae, A.F, Nabais, M.F, Needham, M., Ngo, S.T, Ophoff, R., Qi, T., Restuadi, R., Schultz, D., Steyn, F.J, Thompson, M.J, Turner, B.J, van den Berg, L.H, van Rheenen, W., Veldink, J.H, Wallace, L., Wray, N.R, Wu, Y., Zaitlen, N., Ziser, L.
Published 2022

Genome-wide identification of associations between enhancer and alternative splicing in human and mouse

by Huang, J.-H, Liu, Y.-T, Shiau, C.-K, Tsai, H.-K
Published 2022

Novel population specific autosomal copy number variation and its functional analysis amongst Negritos from Peninsular Malaysia

by Lionel, A.C, Marshall, C.R, Mokhtar, S.S, Peng, H.B, Phipps, M.E, Scherer, S.W, Thiruvahindrapuram, B.
Published 2014

Whole Genome Sequence Analysis of the Plasma Proteome in Black Adults Provides Novel Insights Into Cardiovascular Disease

by Benson, M.D, Bick, A.G, Bouchard, C., Chen, Z.-Z, Correa, A., Cruz, D.E, Deng, S., Durda, P., Farrell, L., Gao, Y., Gerszten, R.E, Guo, X., Hall, M.E, Ida Chen, Y.-D, Jain, D., Johnson, W.C, Katz, D.H, Liu, Y., Manichaikul, A.W, Natarajan, P., National Heart, Lung, and Blood Institute TOPMed (Trans-Omics for Precision Medicine) Consortium, Ngo, D., Pampana, A., Rich, S.S, Robbins, J.M, Rotter, J.I, Sarzynski, M.A, Schmaier, A.A, Shen, D., Sinha, S., Tahir, U.A, Taylor, K.D, Tracy, R.P, Wang, T.J, Wilson, J.G, Yao, J., Yu, Z.
Published 2022

Implementing a Functional Precision Medicine Tumor Board for Acute Myeloid Leukemia

by Aittokallio, T., Brück, O., Dufva, O., Eldfors, S., Gjertsen, B.T, Heckman, C.A, Hellesøy, M., Kallioniemi, O., Kankainen, M., Kivinen, K., Kontro, M., Kumar, A., Kuusanmäki, H., Lehto, M., Malani, D., Mustjoki, S., Parsons, A., Porkka, K., Potdar, S., Räty, R., Saarela, J., Saarela, J., Turunen, L., Västrik, I., Wennerberg, K., Wolf, M., Yadav, B.
Published 2022

Alterations in gut microbiome composition and function in irritable bowel syndrome and increased probiotic abundance with daily supplementation

by Cotter, P., Dietsche, S., Flores, D.V, Gombar, S., Jain, S., Montagne, T., Nair, D., Nguyen, A., Phan, J.
Published 2021

Characterization of LncRNA expression profile and identification of functional LncRNAs associated with unstable angina

by Gu, X., Hou, J., Liu, S., Weng, R., Zhong, Z.
Published 2021

Reanalysis of eMERGE phase III sequence variants in 10,500 participants and infrastructure to support the automated return of knowledge updates

by Harley, J.B, Hawley, M., Jarvik, G.P, Karlson, E.W, Koch, C., Lebo, M.S, Leppig, K.A, Mahanta, L.M, Myers, M.F, Oza, A., Prows, C.A, Rehm, H.L, Vijay Kumar, P.K, Weiss, S.T, Williams, M.S, Yu, W., Zouk, H.
Published 2022

Genetic analysis of over half a million people characterises C-reactive protein loci

by Alizadeh, B.Z, Bodinier, B., Chadeau-Hyam, M., Chasman, D.I, Dehghan, A., Elliott, P., Evangelou, E., Jarvelin, M.-R, Karhunen, V., Koskeridis, F., Ligthart, S., Pazoki, R., Said, S., Sattar, N., Tzoulaki, I., Võsa, U., Welsh, P.
Published 2022

New homozygous gpt delta transgenic rat strain improves an efficiency of the in vivo mutagenicity assay

by Ando, T., Fujiwara, S., Hayashi, H., Honma, M., Masumura, K., Nohmi, T., Suzuki, T., Takagi, H., Ukai, A., Yokose, S., You, X.
Published 2021

Super-variants identification for brain connectivity

by Hu, J., Li, T., Wang, S., Zhang, H.
Published 2021

A Graph Feature Auto-Encoder for the prediction of unobserved node features on biological networks

by Hasibi, R., Michoel, T.
Published 2021

Optimizing network propagation for multi-omics data integration

by Beyer, A., Charmpi, K., Chokkalingam, M., Johnen, R.
Published 2021

The morphometry of left cuneus mediating the genetic regulation on working memory

by Fu, J., He, X., Li, W., Li, X., Liu, H., Qin, W., Xu, J., Ye, Z., Yu, C., Zhang, P.
Published 2021

Oncogenic drivers in 11q13 associated with prognosis and response to therapy in advanced oropharyngeal carcinomas

by Barros-Filho, M.C, Carvalho, A.L, Chulam, T., Drigo, S.A, Hatakeyama, M., Kowalski, L.P, Marchi, F.A, Nicolau, U.R, Pinto, C.A.L, Reis-Rosa, L.A, Rogatto, S.R, Scapulatempo-Neto, C.
Published 2018

Targeted resequencing showing novel common and rare genetic variants increases the risk of asthma in the Chinese Han population

by Cheng, Z., Deng, Y., Fang, S., Li, J., Li, Z., Liu, J., Luo, G., Luo, L., Mo, B., Shu, Y., Wang, Y., Wang, Z., Wei, J., Xiong, W., Yang, H., Yang, J., Yu, B., Zhang, X., Zhu, J.
Published 2021