unclassified drug Article 120 controlled study 105 human 101 Humans 88 genetics 84 metabolism 70 gene expression regulation 66 gene expression 62 male 61 down regulation 57 upregulation 57 adult 56 human cell 56 female 54 nonhuman 51 pathology 50 protein expression 49 human tissue 46 Male 45 Female 44 middle aged 41 Gene Expression Regulation, Neoplastic 40 Middle Aged 39 major clinical study 39 microRNA 37 cell proliferation 34 real time polymerase chain reaction 34 MicroRNAs 32 in vitro study 31