Development and Applications of CRISPR-Cas9 for Genome Engineering

by Hsu, Patrick, Lander, Eric Steven, Zhang, Feng
Published 2017

Multiplex Genome Engineering Using CRISPR/Cas Systems

by Cong, Le, Ran, F. Ann, Cox, David Daniel, Lin, Shuailiang, Barretto, Robert, Habib, Naomi, Hsu, Patrick, Wu, Xuebing, Jiang, Wenyan, Marraffini, Luciano A., Zhang, Feng
Published 2016

Application of CRISPR genetic screens to investigate neurological diseases

by So, Raphaella W L, Chung, Sai W, Lau, Heather H C, Watts, Jeremy J, Gaudette, Erin, Al-Azzawi, Zaid A M, Bishay, Jossana, Lin, Lilian T, Joung, Julia, Wang, Xinzhu, Schmitt-Ulms, Gerold
Published 2020

Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

by Konermann, Silvana, Brigham, Mark D., Trevino, Alexandro E., Joung, Julia, Barcena, Clea, Hsu, Patrick D., Habib, Naomi, Gootenberg, Jonathan S., Nishimasu, Hiroshi, Nureki, Osamu, Zhang, Feng, Abudayyeh, Omar Osama
Published 2016

All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins

by Hochbaum, Daniel R, Zhao, Yongxin, Farhi, Samouil L, Werley, Christopher A, Kapoor, Vikrant, Zou, Peng, Kralj, Joel M, Maclaurin, Dougal, Smedemark-Margulies, Niklas, Saulnier, Jessica L, Boulting, Gabriella L, Straub, Christoph, Melkonian, Michael, Wong, Gane Ka-Shu, Harrison, D Jed, Murthy, Venkatesh N, Sabatini, Bernardo L, Campbell, Robert E, Cohen, Adam E, Klapoetke, Nathan Cao, Cho, Yongku, Boyden, Edward
Published 2017

Implications of human genetic variation in CRISPR-based therapeutic genome editing

by Scott, David A, Zhang, Feng
Published 2020

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

by Lee, M. N., Ye, C., Villani, A.-C, Raj, T., Li, W., Eisenhaure, Thomas, Imboywa, S. H., Chipendo, P. I., Slowikowski, K., Raddassi, K., McCabe, C., Lee, M. H., Frohlich, I. Y., Raychaudhuri, S., Stranger, B. E., Benoist, Christophe, De Jager, Philip L., Hacohen, Nir, Ran, F. Ann, Zhang, Feng, Regev, Aviv, Hafler, David A., Ward, Lucas D., Kellis, Manolis
Published 2015

A fully genetically encoded protein architecture for optical control of peptide ligand concentration

by Schmidt, Daniel, Tillberg, Paul W., Chen, Fei, Boyden, Edward
Published 2014

Synthetic Physiology: Strategies for Adapting Tools from Nature for Genetically Targeted Control of Fast Biological Processes [Chapter 18]

by Chow, Brian Yichiun, Chuong, Amy S., Klapoetke, Nathan Cao, Boyden, Edward Stuart
Published 2016

In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9

by Swiech, Lukasz, Heidenreich, Matthias, Banerjee, Abhishek, Habib, Naomi, Li, Yinqing, Trombetta, John, Sur, Mriganka, Zhang, Feng
Published 2016

High-throughput functional genomics using CRISPR-Cas9

by Shalem, Ophir, Zhang, Feng, Sanjana, Neville
Published 2016

Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening

by Joung, Julia, Konermann, Silvana M, Gootenberg, Jonathan S, Abudayyeh, Omar Osama, Platt, Randall Jeffrey, Brigham, Mark D, Sanjana, Neville E, Zhang, Feng
Published 2017

Rapid and accurate species identification for ecological studies and monitoring using CRISPR-based SHERLOCK

by Baerwald, MR, Goodbla, AM, Nagarajan, RP, Gootenberg, Jonathan S, Abudayyeh, Omar O., Zhang, Feng, Schreier, AD
Published 2021

Hypoxia as a therapy for mitochondrial disease

by Jain, I. H., Zazzeron, L., Goli, R., Alexa, K., Schatzman-Bone, S., Dhillon, H., Goldberger, O., Peng, J., Goessling, W., Zapol, W. M., Mootha, V. K., Shalem, Ophir, Sanjana, Neville E, Zhang, Feng
Published 2017

Optical Pooled Screens in Human Cells

by Feldman, David, Singh, Avtar, Schmid-Burgk, Jonathan, Carlson, Rebecca J., Mezger, Anja, Garrity, Anthony J., Zhang, Feng, Blainey, Paul C
Published 2020

Applications of CRISPR-Cas systems in neuroscience

by Heidenreich, Matthias, Zhang, Feng
Published 2017

Diversity and evolution of class 2 CRISPR-Cas systems

by Shmakov, Sergey, Smargon, Aaron Andrew, Scott, David (David Arthur), Cox, David D., Pyzocha, Neena, Yan, Winston Xia, Abudayyeh, Omar O., Gootenberg, Jonathan S, Makarova, Kira S., Wolf, Yuri I., Severinov, Konstantin, Zhang, Feng, Koonin, Eugene V.
Published 2020

Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons

by Tekin, Halil, Simmons, Sean, Cummings, Beryl, Gao, Linyi, Adiconis, Xian, Hession, Cynthia C., Ghoshal, Ayan, Dionne, Danielle, Choudhury, Sourav, Yesilyurt, Volkan, Sanjana, Neville E, Shi, Xi, Lu, Congyi, Heidenreich, Matthias, Pan, Jen Q., Levin, Joshua Z., Zhang, Feng
Published 2020

Rapid neurogenesis through transcriptional activation in human stem cells

by Guye, Patrick, Li, Yinqing, Weiss, Ron, Busskamp, Volker, Lewis, Nathan E., Ng, Alex H. M., Shipman, Seth L., Byrne, Susan M., Li, Shangzhong, Stadler, Michael, Murn, Jernej, Sanjana, Neville E, Church, George M
Published 2014

Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28

by Shmakov, Sergey, Makarova, Kira S., Koonin, Eugene V., Smargon, Aaron Andrew, Cox, David Benjamin Turitz, Pyzocha, Neena, Zheng, Kaijie, Slaymaker, Ian, Gootenberg, Jonathan S, Essletzbichler, Patrick, Zhang, Feng, Abudayyeh, Omar O.
Published 2018