Strategies to Overcome Heparins’ Low Oral Bioavailability

by Ana Rita Neves, Marta Correia-da-Silva, Emília Sousa, Madalena Pinto
Published 2016-06-01

Old Drugs as New Treatments for Neurodegenerative Diseases

by Fernando Durães, Madalena Pinto, Emília Sousa
Published 2018-05-01

Omadacycline: A Newly Approved Antibacterial from the Class of Tetracyclines

by Fernando Durães, Emília Sousa
Published 2019-04-01

Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors

by Fernando Durães, Andreia Palmeira, Bárbara Cruz, Joana Freitas-Silva, Nikoletta Szemerédi, Luís Gales, Paulo Martins da Costa, Fernando Remião, Renata Silva, Madalena Pinto, Gabriella Spengler, Emília Sousa
Published 2021-06-01

BACE-1 and γ-Secretase as Therapeutic Targets for Alzheimer’s Disease

by Miguel A. Maia, Emília Sousa
Published 2019-03-01

Preliminary Virtual Screening Studies to Identify GRP78 Inhibitors Which May Interfere with SARS-CoV-2 Infection

by Andreia Palmeira, Emília Sousa, Aylin Köseler, Ramazan Sabirli, Tarık Gören, İbrahim Türkçüer, Özgür Kurt, Madalena M. Pinto, M. Helena Vasconcelos
Published 2020-06-01

Curcumin as a Modulator of P-Glycoprotein in Cancer: Challenges and Perspectives

by Vanessa Lopes-Rodrigues, Emília Sousa, M. Helena Vasconcelos
Published 2016-11-01

Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice

by Ana Reis-Mendes, José Luís Dores-Sousa, Ana Isabel Padrão, Margarida Duarte-Araújo, José Alberto Duarte, Vítor Seabra, Salomé Gonçalves-Monteiro, Fernando Remião, Félix Carvalho, Emília Sousa, Maria Lourdes Bastos, Vera Marisa Costa
Published 2021-05-01

From Natural Products to New Synthetic Small Molecules: A Journey through the World of Xanthones

by Madalena M. M. Pinto, Andreia Palmeira, Carla Fernandes, Diana I. S. P. Resende, Emília Sousa, Honorina Cidade, Maria Elizabeth Tiritan, Marta Correia-da-Silva, Sara Cravo
Published 2021-01-01

Xanthones Active against Multidrug Resistance and Virulence Mechanisms of Bacteria

by Fernando Durães, Diana I. S. P. Resende, Andreia Palmeira, Nikoletta Szemerédi, Madalena M. M. Pinto, Gabriella Spengler, Emília Sousa
Published 2021-05-01

Synthesis of New Proteomimetic Quinazolinone Alkaloids and Evaluation of Their Neuroprotective and Antitumor Effects

by Solida Long, Diana I. S. P. Resende, Anake Kijjoa, Artur M. S. Silva, Ricardo Fernandes, Cristina P. R. Xavier, M. Helena Vasconcelos, Emília Sousa, Madalena M. M. Pinto
Published 2019-02-01

Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies

by Ana Lopes, Eva Martins, Renata Silva, Madalena M. M. Pinto, Fernando Remião, Emília Sousa, Carla Fernandes
Published 2018-03-01

Tetracyclic Thioxanthene Derivatives: Studies on Fluorescence and Antitumor Activity

by Fernando Durães, Patrícia M. A. Silva, Pedro Novais, Isabel Amorim, Luís Gales, Cátia I. C. Esteves, Samuel Guieu, Hassan Bousbaa, Madalena Pinto, Emília Sousa
Published 2021-05-01

Semi-Synthesis of Small Molecules of Aminocarbazoles: Tumor Growth Inhibition and Potential Impact on p53

by Solida Long, Joana B. Loureiro, Carla Carvalho, Luís Gales, Lucília Saraiva, Madalena M. M. Pinto, Ploenthip Puthongking, Emília Sousa
Published 2021-03-01

Discovery of a New Xanthone against Glioma: Synthesis and Development of (Pro)liposome Formulations

by Ana Alves, Marta Correia-da-Silva, Claúdia Nunes, João Campos, Emília Sousa, Patrícia M. A. Silva, Hassan Bousbaa, Francisca Rodrigues, Domingos Ferreira, Paulo C. Costa, Madalena Pinto
Published 2019-01-01

Lichen Xanthones as Models for New Antifungal Agents

by Diana I. S. P. Resende, Patrícia Pereira-Terra, Ângela S. Inácio, Paulo Martins da Costa, Eugénia Pinto, Emília Sousa, Madalena M. M. Pinto
Published 2018-10-01

Metabolites from Marine-Derived Fungi as Potential Antimicrobial Adjuvants

by Fernando Durães, Nikoletta Szemerédi, Decha Kumla, Madalena Pinto, Anake Kijjoa, Gabriella Spengler, Emília Sousa
Published 2021-08-01

Modulation of Autophagy by a Thioxanthone Decreases the Viability of Melanoma Cells

by Raquel T. Lima, Diana Sousa, Ana M. Paiva, Andreia Palmeira, João Barbosa, Madalena Pedro, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos
Published 2016-10-01

Screening a Small Library of Xanthones for Antitumor Activity and Identification of a Hit Compound which Induces Apoptosis

by João Barbosa, Raquel T. Lima, Diana Sousa, Ana Sara Gomes, Andreia Palmeira, Hugo Seca, Kantima Choosang, Pannee Pakkong, Hassan Bousbaa, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos, Madalena Pedro
Published 2016-01-01

The Antitumor Activity of a Lead Thioxanthone is Associated with Alterations in Cholesterol Localization

by Raquel T. Lima, Diana Sousa, Ana Sara Gomes, Nuno Mendes, Rune Matthiesen, Madalena Pedro, Franklim Marques, Madalena M. Pinto, Emília Sousa, M. Helena Vasconcelos
Published 2018-12-01