simulation article 53 human 51 Humans 37 Article 33 controlled study 25 computer simulation 21 Computer Simulation 19 biological model 18 nonhuman 18 Computational Biology 17 biology 17 algorithm 14 female 14 male 14 procedures 14 adult 13 statistical model 13 physiology 12 human experiment 11 prediction 11 Markov chain 10 genetics 10 stochastic model 10 Bayes Theorem 9 Bayes theorem 9 Models, Biological 9 Simulation 9 mathematical model 9 validation process 9