Expansion microscopy: principles and uses in biological research

by Wassie, Asmamaw T., Zhao, Yongxin, Boyden, Edward
Published 2021

A case for more curiosity-driven basic research

by Amon, Angelika B
Published 2015

Inter-individual variation in DNA repair capacity: A need for multi-pathway functional assays to promote translational DNA repair research

by Nagel, Zachary D., Chaim, Isaac Alexander, Samson, Leona D
Published 2015

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

by Chen, Walter W., Marjanovic, Nemanja, Zoncu, Roberto, Katajisto, Pekka, Dohla, Julia, Chaffer, Christine L., Pentinmikko, Nalle, Iqbal, Sharif, Weinberg, Robert A, Sabatini, David
Published 2015

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy

by Jonas, Oliver, Singh, Surya P., Lammers, Alex, Dasari, Ramachandra R., So, Peter T. C., Nguyen, Freddy T., Langer, Robert S, Kang, Jeon Woong, Cima, Michael J.
Published 2018

Aneuploidy: Cancer's Fatal Flaw?

by Williams, Bret R., Amon, Angelika B
Published 2012

Roles for Innate Immunity in Combination Immunotherapies

by Moynihan, Kelly Dare, Irvine, Darrell J
Published 2018

Amino acids and mTORC1: from lysosomes to disease

by Efeyan, Alejo, Zoncu, Roberto, Sabatini, David
Published 2017

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

by Lamming, Dudley W., Ye, Lan, Katajisto, Pekka, Goncalves, Marcus D., Saitoh, Maki, Stevens, Deanna M., Davis, James G., Salmon, Adam B., Richardson, Arlan, Ahima, Rexford S., Guertin, David A., Baur, Joseph A., Sabatini, David
Published 2014

Colorectal cancer models for novel drug discovery

by Golovko, Daniel, Kedrin, Dmitriy, Yilmaz, Omer, Roper, Jatin
Published 2016

A Convergent Synthetic Platform for Single-Nanoparticle Combination Cancer Therapy: Ratiometric Loading and Controlled Release of Cisplatin, Doxorubicin, and Camptothecin

by Liao, Longyan, Liu, Jenny, Morton, Stephen Winford, Hammond, Paula T., Johnson, Jeremiah A., Dreaden, Erik Christopher, Shopsowitz, Kevin
Published 2015

Persistent Antigen and Prolonged AKT-mTORC1 Activation Underlie Memory CD8 T Cell Impairment in the Absence of CD4 T Cells

by Li, Yingzhong, Shen, Chase, Zhu, Bingdong, Chen, Jianzhu, Shi, Feng, Eisen, Herman N.
Published 2017

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

by Settembre, Carmine, Zoncu, Roberto, Medina, Diego L., Vetrini, Francesco, Erdin, Serkan, Erdin, SerpilUckac, Huynh, Tuong, Ferron, Mathieu, Karsenty, Gerard, Vellard, Michel C., Facchinetti, Valeria, Ballabio, Andrea, Ballabio, Andrea, Sabatini, David
Published 2015

Human CD34+ CD133+ Hematopoietic Stem Cells Cultured with Growth Factors Including Angptl5 Efficiently Engraft Adult NOD-SCID Il2rγ−/− (NSG) Mice

by Drake, Adam, Khoury, Maroun, Leskov, Ilya B., Iliopoulou, Bettina P., Fragoso, Maria F., Lodish, Harvey F., Chen, Jianzhu
Published 2011

Tracing Compartmentalized NADPH Metabolism in the Cytosol and Mitochondria of Mammalian Cells

by Lewis, Caroline A, Parker, Seth J, Fiske, Brian Prescott, McCloskey, Douglas, Gui, Dan Yi, Green, Courtney R., Feist, Adam M., Vander Heiden, Matthew G., Metallo, Christian M., Vokes, Natalie I., Lewis, Caroline
Published 2016

SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance

by Kami, Kenjiro, Shelton, Laura M., Ramkissoon, Shakti H., Ligon, Keith L., Snuderl, Matija, Kim, Dohoon, Fiske, Brian Prescott, Birsoy, Kivanc, Freinkman, Elizaveta, Possemato, Richard, Chudnovsky, Yakov, Chen, Walter W., Cantor, Jason R., Gui, Dan Yi, Kwon, ManJae, Kang, Seong Woo, Vander Heiden, Matthew G., Sabatini, David, Pacold, Michael Edward
Published 2017

Nutrient-sensing mechanisms and pathways

by Efeyan, Alejo, Comb, William C., Sabatini, David
Published 2015

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening

by Wang, Guangchuan, Chow, Ryan D., Ye, Lupeng, Guzman, Christopher D., Dai, Xiaoyun, Dong, Matthew B., Zhang, Feng, Platt, Randall Jeffrey, Chen, Sidi, Sharp, Phillip A.
Published 2018

mTOR Signaling in Growth Control and Disease

by Laplante, Mathieu, Sabatini, David M, Sabatini, David
Published 2014

Engineering humanized mice for improved hematopoietic reconstitution

by Drake, Adam, Chen, Jianzhu, Chen, Qingfeng
Published 2013