Co-trimoxazole to reduce mortality, transplant, or unplanned hospitalisation in people with moderate to very severe idiopathic pulmonary fibrosis: the EME-TIPAC RCT

by Andrew M Wilson, Allan B Clark, Anthony Cahn, Edwin R Chilvers, William Fraser, Matthew Hammond, David M Livermore, Toby M Maher, Helen Parfrey, Ann Marie Swart, Susan Stirling, David Thickett, Moira Whyte
Published 2021-07-01

Long-term monitoring in primary care for chronic kidney disease and chronic heart failure: a multi-method research programme

by Rafael Perera, Richard Stevens, Jeffrey K Aronson, Amitava Banerjee, Julie Evans, Benjamin G Feakins, Susannah Fleming, Paul Glasziou, Carl Heneghan, FD Richard Hobbs, Louise Jones, Milena Kurtinecz, Daniel S Lasserson, Louise Locock, Julie McLellan, Borislava Mihaylova, Christopher A O’Callaghan, Jason L Oke, Nicola Pidduck, Annette Plüddemann, Nia Roberts, Iryna Schlackow, Brian Shine, Claire L Simons, Clare J Taylor, Kathryn S Taylor, Jan Y Verbakel, Clare Bankhead
Published 2021-08-01

School-based interventions to prevent anxiety, depression and conduct disorder in children and young people: a systematic review and network meta-analysis

by Deborah M Caldwell, Sarah R Davies, Joanna C Thorn, Jennifer C Palmer, Paola Caro, Sarah E Hetrick, David Gunnell, Sumayya Anwer, José A López-López, Clare French, Judi Kidger, Sarah Dawson, Rachel Churchill, James Thomas, Rona Campbell, Nicky J Welton
Published 2021-07-01

Defining phenotypes and treatment effect heterogeneity to inform acute respiratory distress syndrome and sepsis trials: secondary analyses of three RCTs

by Manu Shankar-Hari, Shalini Santhakumaran, A Toby Prevost, Josie K Ward, Timothy Marshall, Claire Bradley, Carolyn S Calfee, Kevin L Delucchi, Pratik Sinha, Michael A Matthay, Jonathan Hackett, Cliona McDowell, John G Laffey, Anthony Gordon, Cecilia M O’Kane, Daniel F McAuley
Published 2021-07-01

Emergent aneurysm treatment compared with treatment on neurological improvement in patients with ruptured poor-grade aneurysmal subarachnoid haemorrhage: the TOPSAT2 RCT

by Philip White, Barbara Gregson, Elaine McColl, Paul Brennan, Alison Steel, Philippa Watts, Ruth Wood, Clare Bowes, Mohsen Javadpour, Amanda Weston, Dipayan Mitra
Published 2021-07-01

Improving the diagnosis and management of Lewy body dementia: the DIAMOND-Lewy research programme including pilot cluster RCT

by John T O’Brien, John-Paul Taylor, Alan Thomas, Claire Bamford, Luke Vale, Sarah Hill, Louise Allan, Tracy Finch, Richard McNally, Louise Hayes, Ajenthan Surendranathan, Joseph Kane, Alexandros E Chrysos, Allison Bentley, Sally Barker, James Mason, David Burn, Ian McKeith
Published 2021-07-01

Venous access devices for the delivery of long-term chemotherapy: the CAVA three-arm RCT

by Olivia Wu, Elaine McCartney, Robert Heggie, Evi Germeni, James Paul, Eileen Soulis, Susan Dillon, Caoimhe Ryan, Moira Sim, Judith Dixon-Hughes, Roshan Agarwal, Andrew Bodenham, Tobias Menne, Brian Jones, Jonathan Moss
Published 2021-07-01

Digitally supported CBT to reduce paranoia and improve reasoning for people with schizophrenia-spectrum psychosis: the SlowMo RCT

by Philippa Garety, Thomas Ward, Richard Emsley, Kathryn Greenwood, Daniel Freeman, David Fowler, Elizabeth Kuipers, Paul Bebbington, Graham Dunn, Amy Hardy
Published 2021-08-01

Practice nurse-supported weight self-management delivered within the national child immunisation programme for postnatal women: a feasibility cluster RCT

by Amanda J Daley, Kate Jolly, Natalie Ives, Susan A Jebb, Sarah Tearne, Sheila M Greenfield, Lucy Yardley, Paul Little, Natalie Tyldesley-Marshall, Hannah Bensoussane, Ruth V Pritchett, Emma Frew, Helen M Parretti
Published 2021-08-01

Progressive exercise compared with best-practice advice, with or without corticosteroid injection, for rotator cuff disorders: the GRASP factorial RCT

by Sally Hopewell, David J Keene, Peter Heine, Ioana R Marian, Melina Dritsaki, Lucy Cureton, Susan J Dutton, Helen Dakin, Andrew Carr, Willie Hamilton, Zara Hansen, Anju Jaggi, Chris Littlewood, Karen Barker, Alastair Gray, Sarah E Lamb
Published 2021-08-01

Family and health-care professionals managing medicines for patients with serious and terminal illness at home: a qualitative study

by Kristian Pollock, Eleanor Wilson, Glenys Caswell, Asam Latif, Alan Caswell, Anthony Avery, Claire Anderson, Vincent Crosby, Christina Faull
Published 2021-08-01

Home environmental assessments and modification delivered by occupational therapists to reduce falls in people aged 65 years and over: the OTIS RCT

by Sarah Cockayne, Alison Pighills, Joy Adamson, Caroline Fairhurst, Shelley Crossland, Avril Drummond, Catherine E Hewitt, Sara Rodgers, Sarah J Ronaldson, Jennifer McCaffery, Katie Whiteside, Arabella Scantlebury, Lyn Robinson-Smith, Ann Cochrane, Sarah E Lamb, Sophie Boyes, Simon Gilbody, Clare Relton, David J Torgerson
Published 2021-07-01

Intensive therapy for moderate established rheumatoid arthritis: the TITRATE research programme

by David L Scott, Fowzia Ibrahim, Harry Hill, Brian Tom, Louise Prothero, Rhiannon R Baggott, Ailsa Bosworth, James B Galloway, Sofia Georgopoulou, Naomi Martin, Isabel Neatrour, Elena Nikiphorou, Jackie Sturt, Allan Wailoo, Frances MK Williams, Ruth Williams, Heidi Lempp
Published 2021-08-01

Increasing specialist intensity at weekends to improve outcomes for patients undergoing emergency hospital admission: the HiSLAC two-phase mixed-methods study

by Julian Bion, Cassie Aldridge, Chris Beet, Amunpreet Boyal, Yen-Fu Chen, Michael Clancy, Alan Girling, Timothy Hofer, Joanne Lord, Russell Mannion, Peter Rees, Chris Roseveare, Louise Rowan, Gavin Rudge, Jianxia Sun, Elizabeth Sutton, Carolyn Tarrant, Mark Temple, Sam Watson, Janet Willars, Richard Lilford
Published 2021-07-01

The Arabin pessary to prevent preterm birth in women with a twin pregnancy and a short cervix: the STOPPIT 2 RCT

by Jane E Norman, John Norrie, Graeme MacLennan, David Cooper, Sonia Whyte, Sushila Chowdhry, Sarah Cunningham-Burley, Aileen R Neilson, Xue W Mei, Joel BE Smith, Andrew Shennan, Stephen C Robson, Steven Thornton, Mark D Kilby, Neil Marlow, Sarah J Stock, Philip R Bennett, Jane Denton
Published 2021-07-01

Prognostic biomarkers to identify patients likely to develop severe Crohn’s disease: a systematic review

by Steve Halligan, Darren Boone, Lucinda Archer, Tariq Ahmad, Stuart Bloom, Manuel Rodriguez-Justo, Stuart A Taylor, Sue Mallett
Published 2021-07-01

Provision of the progestogen-only pill by community pharmacies as bridging contraception for women receiving emergency contraception: the Bridge-it RCT

by Sharon T Cameron, Anna Glasier, Lisa McDaid, Andrew Radley, Susan Patterson, Paula Baraitser, Judith Stephenson, Richard Gilson, Claire Battison, Kathleen Cowle, Thenmalar Vadiveloo, Anne Johnstone, Alessandra Morelli, Beatriz Goulao, Mark Forrest, Alison McDonald, John Norrie
Published 2021-05-01

A school-based, peer-led programme to increase physical activity among 13- to 14-year-old adolescents: the GoActive cluster RCT

by Kirsten L Corder, Helen E Brown, Caroline HD Croxson, Stephanie T Jong, Stephen J Sharp, Anna Vignoles, Paul O Wilkinson, Edward CF Wilson, Esther MF van Sluijs
Published 2021-04-01

Probiotics to reduce antibiotic administration in care home residents aged 65 years and older: the PRINCESS RCT

by Christopher C Butler, Eleri Owen-Jones, Mandy Lau, David Gillespie, Mark Lown, Philip C Calder, Helen Stanton, Mandy Wootton, Vivian Castro Herrera, Antony Bayer, Jane Davies, Alison Edwards, Mina Davoudianfar, Heather Rutter, Kerenza Hood, Michael Moore, Paul Little, Victoria Shepherd, Rachel Lowe, Elizabeth A Miles, Julia Townson, FD Richard Hobbs, Nick A Francis
Published 2021-04-01

Enzyme-linked immunosorbent assays for monitoring TNF-alpha inhibitors and antibody levels in people with rheumatoid arthritis: a systematic review and economic evaluation

by Irina A Tikhonova, Huiqin Yang, Segun Bello, Andrew Salmon, Sophie Robinson, Mohsen Rezaei Hemami, Sophie Dodman, Andriy Kharechko, Richard C Haigh, Meghna Jani, Timothy J McDonald, Martin Hoyle
Published 2021-02-01