Search Results - Adam J. Mead
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Single cell genomics in chronic myeloid leukemia by Adam J. Mead
Published in HemaSphere (2018-06-01)Get full text
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Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis by Nikolaos Sousos, Gemma Buck, Alba Rodriguez-Meira, Ruggiero Norfo, Angela Hamblin, Francesco Pezzella, Jennifer Davies, Philip Hublitz, Bethan Psaila, Adam J. Mead
Published in HemaSphere (2020-06-01)Get full text
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Longitudinal trends of peripheral blood counts in polycythaemia vera and essential thrombocythemia patients in the UK by Lewis Carpenter, Patrick Rockenschaub, Grace B. Hatton, Sofia D'Abrantes, Edward Sims, Nicholas Scott‐Ram, Aurélie Ducès, Gabrielle Emanuel, Adam J. Mead, Mark W. Drummond, Nadezda Lipunova
Published in eJHaem (2022-08-01)Get full text
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4
Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by Graham McIlroy, Charlotte Gaskell, Aimee Jackson, Emily Yafai, Rachel Tasker, Catherine Thomas, Sonia Fox, Rebecca Boucher, Fitsum Ghebretinsea, Claire Harrison, Adam J. Mead, Mary Frances McMullin
Published in BMC Cancer (2025-01-01)Get full text
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The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission by Sandrine Jeanpierre, Kawtar Arizkane, Supat Thongjuea, Elodie Grockowiak, Kevin Geistlich, Lea Barral, Thibault Voeltzel, Anissa Guillemin, Sandrine Gonin-Giraud, Olivier Gandrillon, Franck-Emmanuel Nicolini, Adam J. Mead, Véronique Maguer-Satta, Sylvain Lefort
Published in Haematologica (2020-01-01)Get full text
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Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation by Cristina Di Genua, Ruggiero Norfo, Alba Rodriguez-Meira, Wei Xiong Wen, Roy Drissen, Christopher A.G. Booth, Benjamin Povinelli, Emmanouela Repapi, Nicki Gray, Joana Carrelha, Laura M. Kettyle, Lauren Jamieson, Wen Hao Neo, Supat Thongjuea, Claus Nerlov, Adam J. Mead
Published in Haematologica (2019-11-01)Get full text
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Changes in bone marrow fibrosis during momelotinib or ruxolitinib therapy do not correlate with efficacy outcomes in patients with myelofibrosis by Stephen T. Oh, Srdan Verstovsek, Vikas Gupta, Uwe Platzbecker, Timothy Devos, Jean‐Jacques Kiladjian, Donal P. McLornan, Andrew Perkins, Maria Laura Fox, Mary Frances McMullin, Adam J. Mead, Miklos Egyed, Jiri Mayer, Tomasz Sacha, Jun Kawashima, Mei Huang, Bryan Strouse, Ruben Mesa
Published in eJHaem (2024-02-01)Get full text
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SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2 by Hyun-Ju Cho, Joy Smith, Christopher H Switzer, Eleni Louka, Rebecca L Charles, Oleksandra Prysyazhna, Ewald Schroder, Mariana Fernandez-Caggiano, Daniel Simoes de Jesus, Seda Eminaga, Xiaoke Yin, Xiaoping Yang, Steven Lynham, Manuel Mayr, Valle Morales, Katiuscia Bianchi, Vinothini Rajeeve, Pedro R Cutillas, Adam J Mead, Philip Eaton
Published in EMBO Molecular Medicine (2025-07-01)Get full text
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Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner by Tiago C. Luis, Nikolaos Barkas, Joana Carrelha, Alice Giustacchini, Stefania Mazzi, Ruggiero Norfo, Bishan Wu, Affaf Aliouat, Jose A. Guerrero, Alba Rodriguez-Meira, Tiphaine Bouriez-Jones, Iain C. Macaulay, Maria Jasztal, Guangheng Zhu, Heyu Ni, Matthew J. Robson, Randy D. Blakely, Adam J. Mead, Claus Nerlov, Cedric Ghevaert, Sten Eirik W. Jacobsen
Published in Nature Communications (2023-09-01)Get full text
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Symptomatic benefit of momelotinib in patients with myelofibrosis: Results from the SIMPLIFY phase III studies by Ruben A. Mesa, Stacie Hudgens, Lysbeth Floden, Claire N. Harrison, Jeanne Palmer, Vikas Gupta, Donal P. McLornan, Mary F. McMullin, Jean‐Jaques Kiladjian, Lynda Foltz, Uwe Platzbecker, M. Laura Fox, Adam J. Mead, David M. Ross, Stephen T. Oh, Andrew Perkins, Michael F. Leahy, Samineh Deheshi, Rafe Donahue, Barbara J. Klencke, Srdan Verstovsek
Published in Cancer Medicine (2023-05-01)Get full text
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Patient-reported Outcomes and Quality of Life in Anemic and Symptomatic Patients With Myelofibrosis: Results From the MOMENTUM Study by Ruben A. Mesa, Claire Harrison, Jeanne M. Palmer, Vikas Gupta, Donal P. McLornan, Mary Frances McMullin, Jean-Jacques Kiladjian, Lynda Foltz, Uwe Platzbecker, Maria Laura Fox, Adam J. Mead, David M. Ross, Stephen T. Oh, Andrew Charles Perkins, Michael F. Leahy, Jun Kawashima, Sunhee Ro, Rafe Donahue, Boris Gorsh, Samineh Deheshi, Srdan Verstovsek
Published in HemaSphere (2023-11-01)Get full text
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12
Tamoxifen for the treatment of myeloproliferative neoplasms: A Phase II clinical trial and exploratory analysis by Zijian Fang, Giuditta Corbizi Fattori, Thomas McKerrell, Rebecca H. Boucher, Aimee Jackson, Rachel S. Fletcher, Dorian Forte, Jose-Ezequiel Martin, Sonia Fox, James Roberts, Rachel Glover, Erica Harris, Hannah R. Bridges, Luigi Grassi, Alba Rodriguez-Meira, Adam J. Mead, Steven Knapper, Joanne Ewing, Nauman M. Butt, Manish Jain, Sebastian Francis, Fiona J. Clark, Jason Coppell, Mary F. McMullin, Frances Wadelin, Srinivasan Narayanan, Dragana Milojkovic, Mark W. Drummond, Mallika Sekhar, Hesham ElDaly, Judy Hirst, Maike Paramor, E. Joanna Baxter, Anna L. Godfrey, Claire N. Harrison, Simón Méndez-Ferrer
Published in Nature Communications (2023-11-01)Get full text
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