検索結果 - Aik-Choon Tan

1231 Exploring the landscape of pan-cancer immune-related adverse events through clinical trials big data mining 著者: Aik Choon Tan, Muhammad Z Fadlullah Wilmot

Editorial: AI and data science in drug development and public health: Highlights from the MCBIOS 2022 conference 著者: Ramin Homayouni, Prashanti Manda, Aik Choon Tan, Zhaohui S. Qin

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A Survey of Computational Tools to Analyze and Interpret Whole Exome Sequencing Data 著者: Jennifer D. Hintzsche, William A. Robinson, Aik Choon Tan

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iCOSSY: An Online Tool for Context-Specific Subnetwork Discovery from Gene Expression Data. 著者: Ashis Saha, Minji Jeon, Aik Choon Tan, Jaewoo Kang

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Parkinsons Disease-related Circulating microRNA Biomarkers——a Validation Study 著者: David Petillo, Stephen Orey, Aik Choon Tan, Lars Forsgren, Sok Kean Khoo

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Systems Pharmacology-Based Approach of Connecting Disease Genes in Genome-Wide Association Studies with Traditional Chinese Medicine 著者: Jihye Kim, Minjae Yoo, Jimin Shin, Hyunmin Kim, Jaewoo Kang, Aik Choon Tan

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Comparative Haploid Genetic Screens Reveal Divergent Pathways in the Biogenesis and Trafficking of Glycophosphatidylinositol-Anchored Proteins 著者: Eric M. Davis, Jihye Kim, Bridget L. Menasche, Jacob Sheppard, Xuedong Liu, Aik-Choon Tan, Jingshi Shen

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Downregulated <i>ALDH2</i> Contributes to Tumor Progression and Targeted Therapy Resistance in Human Metastatic Melanoma Cells 著者: Zili Zhai, Takeshi Yamauchi, Karenna Sandoval, Kira Villarreal, Man Wai Charlotte Kwong, Emily J. Swanson, Aik Choon Tan, Mayumi Fujita

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DRPPM-EASY: A Web-Based Framework for Integrative Analysis of Multi-Omics Cancer Datasets 著者: Alyssa Obermayer, Li Dong, Qianqian Hu, Michael Golden, Jerald D. Noble, Paulo Rodriguez, Timothy J. Robinson, Mingxiang Teng, Aik-Choon Tan, Timothy I. Shaw

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An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level. 著者: Xiang Liu, Nancy Gillis, Chang Jiang, Anthony McCofie, Timothy I Shaw, Aik-Choon Tan, Bo Zhao, Lixin Wan, Derek R Duckett, Mingxiang Teng

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Gene partners of the EWSR1 fusion may represent molecularly distinct entities 著者: Victoria Walker, Dexter X. Jin, Sherri Z. Millis, Elham Nasri, Diana A. Corao-Uribe, Aik Choon Tan, Brooke L. Fridley, James L. Chen, Nathan D. Seligson

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Drepmel—A Multi-Omics Melanoma Drug Repurposing Resource for Prioritizing Drug Combinations and Understanding Tumor Microenvironment 著者: Zachary J. Thompson, Jamie K. Teer, Jiannong Li, Zhihua Chen, Eric A. Welsh, Yonghong Zhang, Noura Ayoubi, Zeynep Eroglu, Aik Choon Tan, Keiran S. M. Smalley, Yian Ann Chen

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<i>PARP1</i> and <i>POLD2</i> as prognostic biomarkers for multiple myeloma in autologous stem cell transplant 著者: Melissa Thomas, Junan Li, Kevan King, Avinash K Persaud, Ernest Duah, Zachary Vangundy, Craig C. Hofmeister, Jatinder K. Lamba, Aik Choon Tan, Brooke L. Fridley, Ming J. Poi, Nathan D. Seligson

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A tyrosine kinase inhibitor-induced interferon response positively associates with clinical response in EGFR-mutant lung cancer 著者: Natalia J. Gurule, Caroline E. McCoach, Trista K. Hinz, Daniel T. Merrick, Adriaan Van Bokhoven, Jihye Kim, Tejas Patil, Jacob Calhoun, Raphael A. Nemenoff, Aik Choon Tan, Robert C. Doebele, Lynn E. Heasley

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PATH-SURVEYOR: pathway level survival enquiry for immuno-oncology and drug repurposing 著者: Alyssa N. Obermayer, Darwin Chang, Gabrielle Nobles, Mingxiang Teng, Aik-Choon Tan, Xuefeng Wang, Y. Ann Chen, Steven Eschrich, Paulo C. Rodriguez, G. Daniel Grass, Soheil Meshinchi, Ahmad Tarhini, Dung-tsa Chen, Timothy I. Shaw

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Grading of lung adenocarcinomas with simultaneous segmentation by artificial intelligence (GLASS-AI) 著者: John H. Lockhart, Hayley D. Ackerman, Kyubum Lee, Mahmoud Abdalah, Andrew John Davis, Nicole Hackel, Theresa A. Boyle, James Saller, Aysenur Keske, Kay Hänggi, Brian Ruffell, Olya Stringfield, W. Douglas Cress, Aik Choon Tan, Elsa R. Flores

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Real-world pan-cancer landscape of frameshift mutations and their role in predicting responses to immune checkpoint inhibitors in cancers with low tumor mutational burden 著者: Ignacio Garrido-Laguna, Asaf Maoz, Wungki Park, Abdul Rafeh Naqash, Vaia Florou, Breelyn Wilky, Jonathan Trent, Umang Swami, Garrett Frampton, Heloisa P Soares, Sonam Puri, Aik Choon Tan, Charalampos S Floudas, Carter Norton, Ethan S Sokol, Peter Hosein, Gilberto de Lima Lopes

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Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer 著者: Peter J. Klauck, Stacey M. Bagby, Anna Capasso, Erica L. Bradshaw-Pierce, Heather M. Selby, Anna Spreafico, John J. Tentler, Aik Choon Tan, Jihye Kim, John J. Arcaroli, Alicia Purkey, Wells A. Messersmith, Keisuke Kuida, S. Gail Eckhardt, Todd M. Pitts

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Dramatic Responses to High-Dose Ipilimumab Plus Temozolomide After Progression on Standard- or Low-Dose Ipilimumab in Advanced Melanoma 著者: Julie Williamson, Muhammad Zaki Hidayatullah Fadlullah, Magdalena Kovacsovics-Bankowski, Berit Gibson, Umang Swami, Alyssa Erickson-Wayman, Debra Jamison, Dan Sageser, Joanne Jeter, Tawnya L. Bowles, Donald M. Cannon, Ben Haaland, Joyce D. Schroeder, David A. Nix, Aaron Atkinson, John Hyngstrom, Jordan McPherson, Aik-Choon Tan, Siwen Hu-Lieskovan

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Phase II trial of pembrolizumab, ipilimumab, and aspirin in melanoma: clinical outcomes and translational predictors of response 著者: Zoe Quandt, Saya Jacob, Muhammad Zaki Hidayatullah Fadlullah, Chaorong Wu, Clinton Wu, Laura Huppert, Lauren S. Levine, Paula Sison, Katy K. Tsai, Melissa Chow, Jee Hye Kang, Jimmy Hwang, James C. Lee, Ariel Oglesby, Jessica Venegas, Ben J. Brintz, Aik Choon Tan, Mark S. Anderson, Michael D. Rosenblum, Arabella Young, Adil I. Daud

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