Search Results - Alan A. Melcher

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  1. 1

    Enhancing anti-tumour innate immunity by targeting the DNA damage response and pattern recognition receptors in combination with radiotherapy by Charleen M. L. Chan Wah Hak, Antonio Rullan, Emmanuel C. Patin, Malin Pedersen, Alan A. Melcher, Kevin J. Harrington

    Published in Frontiers in Oncology (2022-08-01)
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  2. 2

    Glycolysis and Fatty Acid Oxidation Inhibition Improves Survival in Glioblastoma by Kelly J. McKelvey, Erica B. Wilson, Susan Short, Alan A. Melcher, Michael Biggs, Connie I. Diakos, Connie I. Diakos, Connie I. Diakos, Viive M. Howell

    Published in Frontiers in Oncology (2021-03-01)
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  3. 3

    The PERK Inhibitor GSK2606414 Enhances Reovirus Infection in Head and Neck Squamous Cell Carcinoma via an ATF4-Dependent Mechanism by Martin McLaughlin, Malin Pedersen, Victoria Roulstone, Katharina F. Bergerhoff, Henry G. Smith, Harriet Whittock, Joan N. Kyula, Magnus T. Dillon, Hardev S. Pandha, Richard Vile, Alan A. Melcher, Kevin J. Harrington

    Published in Molecular Therapy: Oncolytics (2020-03-01)
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  4. 4

    PBRM1 directs PBAF to pericentromeres and protects centromere integrity by Karen A. Lane, Alison Harrod, Lillian Wu, Theodoros I. Roumeliotis, Hugang Feng, Shane Foo, Katheryn A. G. Begg, Federica Schiavoni, Noa Amin, Frank T. Zenke, Alan A. Melcher, Jyoti S. Choudhary, Jessica A. Downs

    Published in Nature Communications (2025-02-01)
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  5. 5

    RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma by Henry G Smith, Kunzah Jamal, Jasbani HS Dayal, Tencho Tenev, Joan Kyula‐Currie, Naomi Guppy, Patrycja Gazinska, Victoria Roulstone, Gianmaria Liccardi, Emma Davies, Ioannis Roxanis, Alan A Melcher, Andrew J Hayes, Gareth J Inman, Kevin J Harrington, Pascal Meier

    Published in EMBO Molecular Medicine (2020-05-01)
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  6. 6

    Combining BRAF inhibition with oncolytic herpes simplex virus enhances the immune-mediated antitumor therapy of BRAF-mutant thyroid cancer by Khin Thway, Kevin J Harrington, Alan A Melcher, Eva Crespo-Rodriguez, Katharina Bergerhoff, Galabina Bozhanova, Shane Foo, Emmanuel C Patin, Harriet Whittock, Richard Buus, Syed Haider, Gareth Muirhead, Kate Newbold, Robert S Coffin, Richard G Vile, Dae Kim, Martin McLaughlin, Malin Pedersen

    Published in Journal for ImmunoTherapy of Cancer (2020-10-01)
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  7. 7

    Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment by Victoria A. Jennings, Reah Rumbold-Hall, Gemma Migneco, Tyler Barr, Katrina Reilly, Nicola Ingram, Isabelle St Hilare, Samuel Heaton, Noura Alzamel, David Jackson, Christy Ralph, Susan Banerjee, Iain McNeish, John C. Bell, Alan A. Melcher, Carolina Ilkow, Graham P. Cook, Fiona Errington-Mais

    Published in Frontiers in Immunology (2024-12-01)
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  8. 8

    Corrigendum: Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprogramming of the tumour microenvironment by Victoria A. Jennings, Reah Rumbold-Hall, Gemma Migneco, Tyler Barr, Katrina Reilly, Nicola Ingram, Isabelle St Hilare, Samuel Heaton, Noura Alzamel, David Jackson, Christy Ralph, Susan Banerjee, Iain McNeish, John C. Bell, Alan A. Melcher, Carolina Ilkow, Graham P. Cook, Fiona Errington-Mais

    Published in Frontiers in Immunology (2025-04-01)
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  9. 9

    Harnessing radiotherapy-induced NK-cell activity by combining DNA damage–response inhibition and immune checkpoint blockade by Simon Smith, Hormas Ghadially, Kevin J Harrington, Alan A Melcher, Isla Leslie, Eva Crespo-Rodriguez, Galabina Bozhanova, Emmanuel C Patin, Harriet Whittock, Martin McLaughlin, Malin Pedersen, James Harper, Pablo Nenclares, Heba Soliman, Magnus T Dillon, Lorna Grove, Davina Northcote, Holly Baldock, Gabriella Baker, Joan Kyula, Jeane Guevara

    Published in Journal for ImmunoTherapy of Cancer (2022-03-01)
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  10. 10

    Tumor control and immune activation through palliative irradiation and ATR inhibition, PATRIOT Part C: a phase Ib trial by Magnus T. Dillon, Emmanuel C. Patin, Kabir Mohammed, Jeane Guevara, Simon A. Smith, Emma Dean, Heba Soliman, Pablo Nenclares, Motoko Ryugenji, Davina Northcote, Neel Shah, Lorna Grove, Christopher J. Lord, Stephen Pettit, Matt Tall, Karen E. Swales, Udai Banerji, Alan A. Melcher, Mark Saunders, Martin D. Forster, Kevin J. Harrington

    Published in Nature Communications (2025-08-01)
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  11. 11

    Sculpting the tumour microenvironment by combining radiotherapy and ATR inhibition for curative-intent adjuvant immunotherapy by Emmanuel C. Patin, Pablo Nenclares, Charleen Chan Wah Hak, Magnus T. Dillon, Anton Patrikeev, Martin McLaughlin, Lorna Grove, Shane Foo, Heba Soliman, Joao P. Barata, Joanna Marsden, Holly Baldock, Jim Gkantalis, Victoria Roulstone, Joan Kyula, Amy Burley, Lisa Hubbard, Malin Pedersen, Simon A. Smith, Eleanor Clancy-Thompson, Alan A. Melcher, Masahiro Ono, Antonio Rullan, Kevin J. Harrington

    Published in Nature Communications (2024-08-01)
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  12. 12

    Updates on radiotherapy-immunotherapy combinations: Proceedings of 8th Annual ImmunoRad Conference by Fereshteh Talebi, Fabiana Gregucci, Jalal Ahmed, Nir Ben Chetrit, Brian D. Brown, Timothy A. Chan, Dhan Chand, Julie Constanzo, Sandra Demaria, Dmitry I. Gabrilovich, Encouse Golden, Andrew Godkin, Chandan Guha, Gaorav P. Gupta, Aisha Hasan, Fernanda G. Herrera, Howard Kaufman, Donna Li, Alan A. Melcher, Sierra McDonald, Taha Merghoub, Arta M. Monjazeb, Sébastien Paris, Sean Pitroda, Anguraj Sadanandam, Dörthe Schaue, Laura Santambrogio, Phillippe Szapary, Julien Sage, James W. Welsh, Anna Wilkins, Kristina H. Young, Eric Wennerberg, Laurence Zitvogel, Lorenzo Galluzzi, Eric Deutsch, Silvia C. Formenti

    Published in OncoImmunology (2025-12-01)
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  13. 13

    Consensus guidelines for the definition, detection and interpretation of immunogenic cell death by Udo S Gaipl, Dmitriy Zamarin, Felipe Prosper, Francesco M Marincola, Alessandra Cesano, Howard L Kaufman, Laurence Zitvogel, Tim Illidge, Taha Merghoub, Sandra Demaria, Abhishek D Garg, Patrizia Agostinis, James W Hodge, George Coukos, Akseli Hemminki, Öystein Rekdal, Jian Han, John Stagg, Sarah Warren, Lorenzo Galluzzi, Dobrin Draganov, Silvia C Formenti, Mark J Smyth, Radek Špíšek, Michael T Lotze, Takahiro Yamazaki, Guido Kroemer, Daolin Tang, Eric Deutsch, Jitka Fucikova, Sofia R Gameiro, Ilio Vitale, Sandy Adjemian, Aitziber Buqué Martinez, Timothy A Chan, Richard L Edelson, Lucia Gabriele, Encouse Golden, Kevin J Harrington, Dewan Md Sakib Hossain, Michael Karin, Oliver Kepp, Juan Jose Lasarte, Sherene Loi, Gwenola Manic, Alan A Melcher, Karen L Mossman, Maria Rescigno, Chiara Riganti, Antonella Sistigu, Bryan E Strauss, Kazuki Tatsuno, Stefaan W van Gool, Peter Vandenabeele

    Published in Journal for ImmunoTherapy of Cancer (2020-05-01)
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