Search Results - Amanda Hunkele

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    Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy by Srijita Bhowmik, Juraj Galeta, Václav Havel, Melissa Nelson, Abdelfattah Faouzi, Benjamin Bechand, Mike Ansonoff, Tomas Fiala, Amanda Hunkele, Andrew C. Kruegel, John. E. Pintar, Susruta Majumdar, Jonathan A. Javitch, Dalibor Sames

    Published in Nature Communications (2021-06-01)
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  2. 2

    Oxa-Iboga alkaloids lack cardiac risk and disrupt opioid use in animal models by Václav Havel, Andrew C. Kruegel, Benjamin Bechand, Scot McIntosh, Leia Stallings, Alana Hodges, Madalee G. Wulf, Mel Nelson, Amanda Hunkele, Michael Ansonoff, John E. Pintar, Christopher Hwu, Rohini S. Ople, Najah Abi-Gerges, Saheem A. Zaidi, Vsevolod Katritch, Mu Yang, Jonathan A. Javitch, Susruta Majumdar, Scott E. Hemby, Dalibor Sames

    Published in Nature Communications (2024-09-01)
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  3. 3

    Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site by Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar

    Published in eLife (2021-02-01)
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