Search Results - Ashraf Brik

Ashraf Brik

Ashraf Brik Ashraf Brik (, ) is a full professor at the Schulich Faculty of Chemistry at the Technion Institute of Technology, Israel. His laboratory specializes in developing synthetic methods for chemical synthesis of proteins with post-translational modifications (PTMs) in quantities that allow for them to be studied thoroughly. Brik's group is developing novel modulators based on small molecules, peptides and peptidomimetics, to influence enzymes (such as deubiquitinases) and proteins involved in various diseases. With the help of these tools, it is possible to understand how molecules and biological systems affect health. Provided by Wikipedia
  • Showing 1 - 5 results of 5
Refine Results
  1. 1

    Wash-free Imaging in Live Cells by Mahdi Hasan, Ashraf Brik

    Published in ACS Central Science (2025-01-01)
    Get full text
    Article


  2. 2

    Antibody for Serine 65 Phosphorylated Ubiquitin Identifies PLK1-Mediated Phosphorylation of Mitotic Proteins and APC1 by Guy Mann, Prasad Sulkshane, Pradeep Sadhu, Tamar Ziv, Michael H. Glickman, Ashraf Brik

    Published in Molecules (2022-07-01)
    Get full text
    Article


  3. 3

    Mechanism of selective recognition of Lys48-linked polyubiquitin by macrocyclic peptide inhibitors of proteasomal degradation by Betsegaw Lemma, Di Zhang, Ganga B. Vamisetti, Bryan G. Wentz, Hiroaki Suga, Ashraf Brik, Jacek Lubkowski, David Fushman

    Published in Nature Communications (2023-11-01)
    Get full text
    Article


  4. 4

    Synthesis and Biological Activity of Novel α-Conotoxins Derived from Endemic Polynesian Cone Snails by Yazid Mohamed Souf, Gonxhe Lokaj, Veeresh Kuruva, Yakop Saed, Delphine Raviglione, Ashraf Brik, Annette Nicke, Nicolas Inguimbert, Sébastien Dutertre

    Published in Marine Drugs (2023-06-01)
    Get full text
    Article


  5. 5

    Histone H3 serine-57 is a CHK1 substrate whose phosphorylation affects DNA repair by Nikolaos Parisis, Pablo D. Dans, Muhammad Jbara, Balveer Singh, Diane Schausi-Tiffoche, Diego Molina-Serrano, Isabelle Brun-Heath, Denisa Hendrychová, Suman Kumar Maity, Diana Buitrago, Rafael Lema, Thiziri Nait Achour, Simona Giunta, Michael Girardot, Nicolas Talarek, Valérie Rofidal, Katerina Danezi, Damien Coudreuse, Marie-Noëlle Prioleau, Robert Feil, Modesto Orozco, Ashraf Brik, Pei-Yun Jenny Wu, Liliana Krasinska, Daniel Fisher

    Published in Nature Communications (2023-08-01)
    Get full text
    Article


Search Tools: