Search Results - Bob C. Lin

Hyaluronidase-enhanced subcutaneous delivery of bNAbs: a phase 1 randomized controlled clinical trial in HIV-uninfected women by Sharana Mahomed, Farzana Osman, Martin Beliveau, Roberto Heredia-Ortiz, Kevin Carlton, Jennifer Wang, Madeeha Mughal, Kwang Low, Sandeep Narpala, Bob C. Lin, Mike Castro, Leonid Serebryannyy, Richard A. Koup, Quarraisha Abdool Karim, Salim S. Abdool Karim

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Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design by Graham T. Holt, Jason Gorman, Siyu Wang, Anna U. Lowegard, Baoshan Zhang, Tracy Liu, Bob C. Lin, Mark K. Louder, Marcel S. Frenkel, Krisha McKee, Sijy O’Dell, Reda Rawi, Chen-Hsiang Shen, Nicole A. Doria-Rose, Peter D. Kwong, Bruce R. Donald

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Structural development of the HIV-1 apex-directed PGT145-PGDM1400 antibody lineage by Rosemarie D. Mason, Baoshan Zhang, Nicholas C. Morano, Chen-Hsiang Shen, Krisha McKee, Ashley Heimann, Renguang Du, Alexandra F. Nazzari, Shelby Hodges, Tapan Kanai, Bob C. Lin, Mark K. Louder, Nicole A. Doria-Rose, Tongqing Zhou, Lawrence Shapiro, Mario Roederer, Peter D. Kwong, Jason Gorman

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Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain by Young D. Kwon, Amarendra Pegu, Eun Sung Yang, Baoshan Zhang, Michael F. Bender, Mangaiarkarasi Asokan, Qingbo Liu, Krisha McKee, Bob C. Lin, Tracy Liu, Mark K. Louder, Reda Rawi, Mateo Reveiz, Andrew J. Schaub, Chen-Hsiang Shen, Nicole A. Doria-Rose, Paolo Lusso, John R. Mascola, Peter D. Kwong

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Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains by Shixia Wang, Kun-Wei Chan, Danlan Wei, Xiuwen Ma, Shuying Liu, Guangnan Hu, Saeyoung Park, Ruimin Pan, Ying Gu, Alexandra F. Nazzari, Adam S. Olia, Kai Xu, Bob C. Lin, Mark K. Louder, Krisha McKee, Nicole A. Doria-Rose, David Montefiori, Michael S. Seaman, Tongqing Zhou, Peter D. Kwong, James Arthos, Xiang-Peng Kong, Shan Lu

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Phenotypic heterogeneity defines B cell responses to repeated SARS-CoV-2 exposures through vaccination and infection by Lela Kardava, James Lim, Clarisa M. Buckner, Felipe Lopes de Assis, Xiaozhen Zhang, Wei Wang, Mattie L. Melnyk, Omar El Merhebi, Krittin Trihemasava, I-Ting Teng, Robin Carroll, Yogita Jethmalani, Mike Castro, Bob C. Lin, Lauren H. Praiss, Catherine A. Seamon, Peter D. Kwong, Richard A. Koup, Leonid Serebryannyy, David C. Nickle, Tae-Wook Chun, Susan Moir

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Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site by Bailey B. Banach, Sergei Pletnev, Adam S. Olia, Kai Xu, Baoshan Zhang, Reda Rawi, Tatsiana Bylund, Nicole A. Doria-Rose, Thuy Duong Nguyen, Ahmed S. Fahad, Myungjin Lee, Bob C. Lin, Tracy Liu, Mark K. Louder, Bharat Madan, Krisha McKee, Sijy O’Dell, Mallika Sastry, Arne Schön, Natalie Bui, Chen-Hsiang Shen, Jacy R. Wolfe, Gwo-Yu Chuang, John R. Mascola, Peter D. Kwong, Brandon J. DeKosky

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Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life by Baoshan Zhang, Deepika Gollapudi, Jason Gorman, Sijy O’Dell, Leland F. Damron, Krisha McKee, Mangaiarkarasi Asokan, Eun Sung Yang, Amarendra Pegu, Bob C. Lin, Cara W. Chao, Xuejun Chen, Lucio Gama, Vera B. Ivleva, William H. Law, Cuiping Liu, Mark K. Louder, Stephen D. Schmidt, Chen-Hsiang Shen, Wei Shi, Judith A. Stein, Michael S. Seaman, Adrian B. McDermott, Kevin Carlton, John R. Mascola, Peter D. Kwong, Q. Paula Lei, Nicole A. Doria-Rose

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A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies by Evan M. Cale, Chen-Hsiang Shen, Adam S. Olia, Nathan A. Radakovich, Reda Rawi, Yongping Yang, David R. Ambrozak, Anthony K. Bennici, Gwo-Yu Chuang, Emma D. Crooks, Jefferson I. Driscoll, Bob C. Lin, Mark K. Louder, Patrick J. Madden, Michael A. Messina, Keiko Osawa, Guillaume B.E. Stewart-Jones, Raffaello Verardi, Zoe Vrakas, Danielle Xie, Baoshan Zhang, James M. Binley, Mark Connors, Richard A. Koup, Theodore C. Pierson, Nicole A. Doria-Rose, Peter D. Kwong, John R. Mascola, Jason Gorman

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Ultrapotent Broadly Neutralizing Human‐llama Bispecific Antibodies against HIV‐1 by Jianliang Xu, Tongqing Zhou, Krisha McKee, Baoshan Zhang, Cuiping Liu, Alexandra F. Nazzari, Amarendra Pegu, Chen‐Hsiang Shen, Jordan E. Becker, Michael F. Bender, Payton Chan, Anita Changela, Ridhi Chaudhary, Xuejun Chen, Tal Einav, Young Do Kwon, Bob C. Lin, Mark K. Louder, Jonah S. Merriam, Nicholas C. Morano, Sijy O'Dell, Adam S. Olia, Reda Rawi, Ryan S. Roark, Tyler Stephens, I‐Ting Teng, Emily Tourtellott‐Fogt, Shuishu Wang, Eun Sung Yang, Lawrence Shapiro, Yaroslav Tsybovsky, Nicole A. Doria‐Rose, Rafael Casellas, Peter D. Kwong

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Virologic effects of broadly neutralizing antibodies VRC01LS and VRC07-523LS on chronic HIV-1 infection by Myra Happe, Rebecca M. Lynch, Carl J. Fichtenbaum, Sonya L. Heath, Susan L. Koletar, Raphael J. Landovitz, Rachel M. Presti, Jorge L. Santana-Bagur, Randall L. Tressler, LaSonji A. Holman, Laura Novik, Jhoanna C. Roa, Ro Shauna Rothwell, Larisa Strom, Jing Wang, Zonghui Hu, Michelle Conan-Cibotti, Anjali M. Bhatnagar, Bridget Dwyer, Sung Hee Ko, Frida Belinky, Aryan M. Namboodiri, Janardan P. Pandey, Robin Carroll, Manjula Basappa, Leonid Serebryannyy, Sandeep R. Narpala, Bob C. Lin, Adrian B. McDermott, Eli A. Boritz, Edmund V. Capparelli, Emily E. Coates, Richard A. Koup, Julie E. Ledgerwood, John R. Mascola, Grace L. Chen, Pablo Tebas, the VRC 607/A5378 Study Team

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Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS by Seemal F. Awan, Amarendra Pegu, Larisa Strom, Cristina A. Carter, Cynthia S. Hendel, LaSonji A. Holman, Pamela J. Costner, Olga Trofymenko, Renunda Dyer, Ingelise J. Gordon, Ro Shauna S. Rothwell, Somia P. Hickman, Michelle Conan-Cibotti, Nicole A. Doria-Rose, Bob C. Lin, Sarah O’Connell, Sandeep R. Narpala, Cassandra G. Almasri, Cuiping Liu, Sungyoul Ko, Young D. Kwon, Aryan M. Namboodiri, Janardan P. Pandey, Frank J. Arnold, Kevin Carlton, Jason G. Gall, Peter D. Kwong, Edmund V. Capparelli, Robert T. Bailer, Adrian B. McDermott, Grace L. Chen, Richard A. Koup, John R. Mascola, Emily E. Coates, Julie E. Ledgerwood, Martin R. Gaudinski, the VRC 610 study team

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Immunogenicity of NVX-CoV2373 heterologous boost against SARS-CoV-2 variants by Kirsten E. Lyke, Robert L. Atmar, Clara Dominguez Islas, Christine M. Posavad, Meagan E. Deming, Angela R. Branche, Christine Johnston, Hana M. El Sahly, Srilatha Edupuganti, Mark J. Mulligan, Lisa A. Jackson, Richard E. Rupp, Christina A. Rostad, Rhea N. Coler, Martín Bäcker, Angelica C. Kottkamp, Tara M. Babu, David Dobrzynski, Judith M. Martin, Rebecca C. Brady, Robert W. Frenck, Kumaravel Rajakumar, Karen Kotloff, Nadine Rouphael, Daniel Szydlo, Rahul PaulChoudhury, Janet I. Archer, Sonja Crandon, Brian Ingersoll, Amanda Eaton, Elizabeth R. Brown, M. Juliana McElrath, Kathleen M. Neuzil, David S. Stephens, Diane J. Post, Bob C. Lin, Leonid Serebryannyy, John H. Beigel, David C. Montefiori, Paul C. Roberts, the DMID 21-0012 Study Group

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Stochastic Interventional Vaccine Efficacy and Principal Surrogate Analyses of Antibody Markers as Correlates of Protection against Symptomatic COVID-19 in the COVE mRNA-1273 Trial by Ying Huang, Nima S. Hejazi, Bryan Blette, Lindsay N. Carpp, David Benkeser, David C. Montefiori, Adrian B. McDermott, Youyi Fong, Holly E. Janes, Weiping Deng, Honghong Zhou, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Britta Flach, Bob C. Lin, Sarah O’Connell, Charlene McDanal, Amanda Eaton, Marcella Sarzotti-Kelsoe, Yiwen Lu, Chenchen Yu, Avi Kenny, Marco Carone, Chuong Huynh, Jacqueline Miller, Hana M. El Sahly, Lindsey R. Baden, Lisa A. Jackson, Thomas B. Campbell, Jesse Clark, Michele P. Andrasik, James G. Kublin, Lawrence Corey, Kathleen M. Neuzil, Rolando Pajon, Dean Follmann, Ruben O. Donis, Richard A. Koup, Peter B. Gilbert, on behalf of the Immune Assays, Moderna, Inc., Coronavirus Vaccine Prevention Network (CoVPN)/Coronavirus Efficacy (COVE), United States Government (USG)/CoVPN Biostatistics Teams

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Neutralizing antibody correlate of protection against severe-critical COVID-19 in the ENSEMBLE single-dose Ad26.COV2.S vaccine efficacy trial by Lindsay N. Carpp, Ollivier Hyrien, Youyi Fong, David Benkeser, Sanne Roels, Daniel J. Stieh, Ilse Van Dromme, Griet A. Van Roey, Avi Kenny, Ying Huang, Marco Carone, Adrian B. McDermott, Christopher R. Houchens, Karen Martins, Lakshmi Jayashankar, Flora Castellino, Obrimpong Amoa-Awua, Manjula Basappa, Britta Flach, Bob C. Lin, Christopher Moore, Mursal Naisan, Muhammed Naqvi, Sandeep Narpala, Sarah O’Connell, Allen Mueller, Leo Serebryannyy, Mike Castro, Jennifer Wang, Christos J. Petropoulos, Alex Luedtke, Yiwen Lu, Chenchen Yu, Michal Juraska, Nima S. Hejazi, Daniel N. Wolfe, Jerald Sadoff, Glenda E. Gray, Beatriz Grinsztejn, Paul A. Goepfert, Linda-Gail Bekker, Aditya H. Gaur, Valdilea G. Veloso, April K. Randhawa, Michele P. Andrasik, Jenny Hendriks, Carla Truyers, An Vandebosch, Frank Struyf, Hanneke Schuitemaker, Macaya Douoguih, James G. Kublin, Lawrence Corey, Kathleen M. Neuzil, Dean Follmann, Richard A. Koup, Ruben O. Donis, Peter B. Gilbert, On behalf of the Immune Assays Team, the Coronavirus Vaccine Prevention Network (CoVPN)/ENSEMBLE Team, the United States Government (USG)/CoVPN Biostatistics Team

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