Search Results - Bryan L Roth

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  1. 1

    The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice by Vladimir M. Pogorelov, Ramona M. Rodriguiz, Ramona M. Rodriguiz, Bryan L. Roth, Bryan L. Roth, William C. Wetsel, William C. Wetsel, William C. Wetsel

    Published in Frontiers in Molecular Biosciences (2023-10-01)
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  2. 2

    Agonist and antagonist TRUPATH assays for G protein-coupled receptors by Jeffrey F. DiBerto, Katie Smart, Reid H.J. Olsen, Bryan L. Roth

    Published in STAR Protocols (2022-06-01)
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  3. 3

    The ketamine analogue methoxetamine and 3- and 4-methoxy analogues of phencyclidine are high affinity and selective ligands for the glutamate NMDA receptor. by Bryan L Roth, Simon Gibbons, Warunya Arunotayanun, Xi-Ping Huang, Vincent Setola, Ric Treble, Les Iversen

    Published in PLoS ONE (2013-01-01)
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  4. 4

    Isoquinoline Alkaloids Isolated from Corydalis yanhusuo and Their Binding Affinities at the Dopamine D1 Receptor by David Y. W. Lee, Lee-Yuan Liu-Chen, Bryan L. Roth, Niels H. Jensen, Wei Xu, Zhong-Ze Ma

    Published in Molecules (2008-09-01)
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  5. 5

    A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. by John D Chan, John D McCorvy, Sreemoyee Acharya, Malcolm E Johns, Timothy A Day, Bryan L Roth, Jonathan S Marchant

    Published in PLoS Pathogens (2016-05-01)
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  6. 6

    DREADDs in Drosophila: A Pharmacogenetic Approach for Controlling Behavior, Neuronal Signaling, and Physiology in the Fly by Jaime Becnel, Oralee Johnson, Zana R. Majeed, Vi Tran, Bangning Yu, Bryan L. Roth, Robin L. Cooper, Edmund K. Kerut, Charles D. Nichols

    Published in Cell Reports (2013-09-01)
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  7. 7

    Selective κ opioid antagonists nor-BNI, GNTI and JDTic have low affinities for non-opioid receptors and transporters. by Thomas A Munro, Xi-Ping Huang, Carmela Inglese, Maria Grazia Perrone, Ashlee Van't Veer, F Ivy Carroll, Cécile Béguin, William A Carlezon, Nicola A Colabufo, Bruce M Cohen, Bryan L Roth

    Published in PLoS ONE (2013-01-01)
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  8. 8

    Psychedelic compounds directly excite 5-HT2A layer V medial prefrontal cortex neurons through 5-HT2A Gq activation by Gavin P. Schmitz, Yi-Ting Chiu, Mia L. Foglesong, Sarah N. Magee, Martin MacKinnon, Gabriele M. König, Evi Kostenis, Li-Ming Hsu, Yen-Yu I. Shih, Bryan L. Roth, Melissa A. Herman

    Published in Translational Psychiatry (2025-10-01)
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  9. 9

    A proximity proteomics pipeline with improved reproducibility and throughput by Xiaofang Zhong, Qiongyu Li, Benjamin J Polacco, Trupti Patil, Aaron Marley, Helene Foussard, Prachi Khare, Rasika Vartak, Jiewei Xu, Jeffrey F DiBerto, Bryan L Roth, Manon Eckhardt, Mark von Zastrow, Nevan J Krogan, Ruth Hüttenhain

    Published in Molecular Systems Biology (2024-07-01)
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  10. 10

    Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism by Madigan L. Bedard, Xi-Ping Huang, Jackson G. Murray, Alexandra C. Nowlan, Sara Y. Conley, Sarah E. Mott, Samuel J. Loyack, Calista A. Cline, Caroline G. Clodfelter, Nabarun Dasgupta, Brian Krumm, Bryan L. Roth, Zoe A. McElligott

    Published in Addiction Neuroscience (2024-06-01)
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  11. 11

    The structural diversity of psychedelic drug actions revealed by Ryan H. Gumpper, Manish K. Jain, Kuglae Kim, Renhong Sun, Ning Sun, Zhongli Xu, Jeffrey F. DiBerto, Brian E. Krumm, Nicholas J. Kapolka, H. Ümit Kaniskan, David E. Nichols, Jian Jin, Jonathan F. Fay, Bryan L. Roth

    Published in Nature Communications (2025-03-01)
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  12. 12

    HypoRiPPAtlas as an Atlas of hypothetical natural products for mass spectrometry database search by Yi-Yuan Lee, Mustafa Guler, Desnor N. Chigumba, Shen Wang, Neel Mittal, Cameron Miller, Benjamin Krummenacher, Haodong Liu, Liu Cao, Aditya Kannan, Keshav Narayan, Samuel T. Slocum, Bryan L. Roth, Alexey Gurevich, Bahar Behsaz, Roland D. Kersten, Hosein Mohimani

    Published in Nature Communications (2023-07-01)
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  13. 13

    Corrigendum to “Xylazine is an agonist at kappa opioid receptors and exhibits sex-specific responses to opioid antagonism” [Addiction Neuroscience, Volume 11, June 2024, 100155]... by Madigan L. Bedard, Xi-Ping Huang, Jackson G. Murray, Alexandra C. Nowlan, Sara Y. Conley, Sarah E. Mott, Samuel J. Loyack, Calista A. Cline, Caroline G. Clodfelter, Nabarun Dasgupta, Brian Krumm, Bryan L. Roth, Zoe A. McElligott

    Published in Addiction Neuroscience (2024-09-01)
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  14. 14

    Quantitative analysis of focused a-to-I RNA editing sites by ultra-high-throughput sequencing in psychiatric disorders. by Hu Zhu, Daniel J Urban, Jared Blashka, Matthew T McPheeters, Wesley K Kroeze, Piotr Mieczkowski, James C Overholser, George J Jurjus, Lesa Dieter, Gouri J Mahajan, Grazyna Rajkowska, Zefeng Wang, Patrick F Sullivan, Craig A Stockmeier, Bryan L Roth

    Published in PLoS ONE (2012-01-01)
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  15. 15

    High-affinity agonists reveal recognition motifs for the MRGPRD GPCR by Chunyu Wang, Yongfeng Liu, Marion Lanier, Adam Yeager, Isha Singh, Ryan H. Gumpper, Brian E. Krumm, Chelsea DeLeon, Shicheng Zhang, Marcus Boehm, Richard Pittner, Alain Baron, Lisa Dvorak, Corinne Bacon, Brian K. Shoichet, Esther Martinborough, Jonathan F. Fay, Can Cao, Bryan L. Roth

    Published in Cell Reports (2024-12-01)
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  16. 16

    Docking for EP4R antagonists active against inflammatory pain by Stefan Gahbauer, Chelsea DeLeon, Joao M. Braz, Veronica Craik, Hye Jin Kang, Xiaobo Wan, Xi-Ping Huang, Christian B. Billesbølle, Yongfeng Liu, Tao Che, Ishan Deshpande, Madison Jewell, Elissa A. Fink, Ivan S. Kondratov, Yurii S. Moroz, John J. Irwin, Allan I. Basbaum, Bryan L. Roth, Brian K. Shoichet

    Published in Nature Communications (2023-12-01)
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  17. 17

    Structural insights into the human niacin receptor HCA2-Gi signalling complex by Yang Yang, Hye Jin Kang, Ruogu Gao, Jingjing Wang, Gye Won Han, Jeffrey F. DiBerto, Lijie Wu, Jiahui Tong, Lu Qu, Yiran Wu, Ryan Pileski, Xuemei Li, Xuejun Cai Zhang, Suwen Zhao, Terry Kenakin, Quan Wang, Raymond C. Stevens, Wei Peng, Bryan L. Roth, Zihe Rao, Zhi-Jie Liu

    Published in Nature Communications (2023-03-01)
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  18. 18

    A neurodevelopmental disorder mutation locks G proteins in the transitory pre-activated state by Kevin M. Knight, Brian E. Krumm, Nicholas J. Kapolka, W. Grant Ludlam, Meng Cui, Sepehr Mani, Iya Prytkova, Elizabeth G. Obarow, Tyler J. Lefevre, Wenyuan Wei, Ning Ma, Xi-Ping Huang, Jonathan F. Fay, Nagarajan Vaidehi, Alan V. Smrcka, Paul A. Slesinger, Diomedes E. Logothetis, Kirill A. Martemyanov, Bryan L. Roth, Henrik G. Dohlman

    Published in Nature Communications (2024-08-01)
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  19. 19

    Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site by Rajendra Uprety, Tao Che, Saheem A Zaidi, Steven G Grinnell, Balázs R Varga, Abdelfattah Faouzi, Samuel T Slocum, Abdullah Allaoa, András Varadi, Melissa Nelson, Sarah M Bernhard, Elizaveta Kulko, Valerie Le Rouzic, Shainnel O Eans, Chloe A Simons, Amanda Hunkele, Joan Subrath, Ying Xian Pan, Jonathan A Javitch, Jay P McLaughlin, Bryan L Roth, Gavril W Pasternak, Vsevolod Katritch, Susruta Majumdar

    Published in eLife (2021-02-01)
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  20. 20

    Donated chemical probes for open science by Susanne Müller, Suzanne Ackloo, Cheryl H Arrowsmith, Marcus Bauser, Jeremy L Baryza, Julian Blagg, Jark Böttcher, Chas Bountra, Peter J Brown, Mark E Bunnage, Adrian J Carter, David Damerell, Volker Dötsch, David H Drewry, Aled M Edwards, James Edwards, Jon M Elkins, Christian Fischer, Stephen V Frye, Andreas Gollner, Charles E Grimshaw, Adriaan IJzerman, Thomas Hanke, Ingo V Hartung, Steve Hitchcock, Trevor Howe, Terry V Hughes, Stefan Laufer, Volkhart MJ Li, Spiros Liras, Brian D Marsden, Hisanori Matsui, John Mathias, Ronan C O'Hagan, Dafydd R Owen, Vineet Pande, Daniel Rauh, Saul H Rosenberg, Bryan L Roth, Natalie S Schneider, Cora Scholten, Kumar Singh Saikatendu, Anton Simeonov, Masayuki Takizawa, Chris Tse, Paul R Thompson, Daniel K Treiber, Amélia YI Viana, Carrow I Wells, Timothy M Willson, William J Zuercher, Stefan Knapp, Anke Mueller-Fahrnow

    Published in eLife (2018-04-01)
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