Search Results - Caryl E. Sortwell
- Showing 1 - 19 results of 19
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Advancing age and the rs6265 BDNF SNP are permissive to graft-induced dyskinesias in parkinsonian rats by Natosha M. Mercado, Carlye Szarowicz, Jennifer A. Stancati, Caryl E. Sortwell, Samuel A. Boezwinkle, Timothy J. Collier, Margaret E. Caulfield, Kathy Steece-Collier
Published in npj Parkinson's Disease (2024-08-01)Get full text
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Alpha-synuclein inclusion responsive microglia are resistant to CSF1R inhibition by Anna C. Stoll, Christopher J. Kemp, Joseph R. Patterson, Michael Kubik, Nathan Kuhn, Matthew Benskey, Megan F. Duffy, Kelvin C. Luk, Caryl E. Sortwell
Published in Journal of Neuroinflammation (2024-04-01)Get full text
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Neuroinflammatory gene expression profiles of reactive glia in the substantia nigra suggest a multidimensional immune response to alpha synuclein inclusions by Anna C. Stoll, Christopher J. Kemp, Joseph R. Patterson, Jacob W. Howe, Kathy Steece-Collier, Kelvin C. Luk, Caryl E. Sortwell, Matthew J. Benskey
Published in Neurobiology of Disease (2024-02-01)Get full text
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Downregulation of striatal CaV1.3 inhibits the escalation of levodopa-induced dyskinesia in male and female parkinsonian rats of advanced age by Margaret E. Caulfield, Molly J. Vander Werp, Jennifer A. Stancati, Timothy J. Collier, Caryl E. Sortwell, Ivette M. Sandoval, Fredric P. Manfredsson, Kathy Steece-Collier
Published in Neurobiology of Disease (2023-06-01)Get full text
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Impact of age and vector construct on striatal and nigral transgene expression by Nicole K Polinski, Fredric P Manfredsson, Matthew J Benskey, D Luke Fischer, Christopher J Kemp, Kathy Steece-Collier, Ivette M Sandoval, Katrina L Paumier, Caryl E Sortwell
Published in Molecular Therapy: Methods & Clinical Development (2016-01-01)Get full text
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The longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes. by Nicholas M Kanaan, Timothy J Collier, Allyson Cole-Strauss, Tessa Grabinski, Zachary R Mattingly, Mary E Winn, Kathy Steece-Collier, Caryl E Sortwell, Fredric P Manfredsson, Jack W Lipton
Published in PLoS ONE (2015-01-01)Get full text
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Rationally Engineered AAV Capsids Improve Transduction and Volumetric Spread in the CNS by Nicholas M. Kanaan, Rhyomi C. Sellnow, Sanford L. Boye, Ben Coberly, Antonette Bennett, Mavis Agbandje-McKenna, Caryl E. Sortwell, William W. Hauswirth, Shannon E. Boye, Fredric P. Manfredsson
Published in Molecular Therapy: Nucleic Acids (2017-09-01)Get full text
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Morphological and behavioral impact of AAV2/5-mediated overexpression of human wildtype alpha-synuclein in the rat nigrostriatal system. by Sara E Gombash, Fredric P Manfredsson, Christopher J Kemp, Nathan C Kuhn, Sheila M Fleming, Ann E Egan, Laura M Grant, Michelle R Ciucci, Jeffrey P MacKeigan, Caryl E Sortwell
Published in PLoS ONE (2013-01-01)Get full text
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Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory by Emily J. Jaehne, Jessica N. Kent, Emily J. Antolasic, Bradley J. Wright, Jereme G. Spiers, Kerstin C. Creutzberg, Federico De Rosa, Marco A. Riva, Caryl E. Sortwell, Timothy J. Collier, Maarten van den Buuse
Published in Translational Psychiatry (2022-03-01)Get full text
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Developmental exposure to the organochlorine pesticide dieldrin causes male-specific exacerbation of α-synuclein-preformed fibril-induced toxicity and motor deficits by Aysegul O. Gezer, Joseph Kochmanski, Sarah E. VanOeveren, Allyson Cole-Strauss, Christopher J. Kemp, Joseph R. Patterson, Kathryn M. Miller, Nathan C. Kuhn, Danielle E. Herman, Alyssa McIntire, Jack W. Lipton, Kelvin C. Luk, Sheila M. Fleming, Caryl E. Sortwell, Alison I. Bernstein
Published in Neurobiology of Disease (2020-07-01)Get full text
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Next-Generation Diamond Electrodes for Neurochemical Sensing: Challenges and Opportunities by Erin K. Purcell, Michael F. Becker, Yue Guo, Seth A. Hara, Kip A. Ludwig, Collin J. McKinney, Elizabeth M. Monroe, Robert Rechenberg, Cory A. Rusinek, Akash Saxena, James R. Siegenthaler, Caryl E. Sortwell, Cort H. Thompson, James K. Trevathan, Suzanne Witt, Wen Li
Published in Micromachines (2021-01-01)Get full text
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Beta2-adrenoreceptor agonist clenbuterol produces transient decreases in alpha-synuclein mRNA but no long-term reduction in protein by Joseph R. Patterson, Warren D. Hirst, Jacob W. Howe, Christopher P. Russell, Allyson Cole-Strauss, Christopher J. Kemp, Megan F. Duffy, Jared Lamp, Andrew Umstead, Michael Kubik, Anna C. Stoll, Irving E. Vega, Kathy Steece-Collier, Yi Chen, Anne C. Campbell, Catherine L. Nezich, Kelly E. Glajch, Caryl E. Sortwell
Published in npj Parkinson's Disease (2022-05-01)Get full text
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Correction to: Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration by Megan F. Duffy, Timothy J. Collier, Joseph R. Patterson, Christopher J. Kemp, Kelvin C. Luk, Malú G. Tansey, Katrina L. Paumier, Nicholas M. Kanaan, D. Luke Fischer, Nicole K. Polinski, Olivia L. Barth, Jacob W. Howe, Nishant N. Vaikath, Nour K. Majbour, Omar M. A. El-Agnaf, Caryl E. Sortwell
Published in Journal of Neuroinflammation (2018-05-01)Get full text
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Transcriptomic profiling of early synucleinopathy in rats induced with preformed fibrils by Joseph R. Patterson, Joseph Kochmanski, Anna C. Stoll, Michael Kubik, Christopher J. Kemp, Megan F. Duffy, Kajene Thompson, Jacob W. Howe, Allyson Cole-Strauss, Nathan C. Kuhn, Kathryn M. Miller, Seth Nelson, Christopher U. Onyekpe, John S. Beck, Scott E. Counts, Alison I. Bernstein, Kathy Steece-Collier, Kelvin C. Luk, Caryl E. Sortwell
Published in npj Parkinson's Disease (2024-01-01)Get full text
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Intrastriatal injection of alpha-synuclein preformed fibrils to rats results in L-DOPA reversible sensorimotor impairments and alterations in non-motor function by Sheila M. Fleming, Sophia Scott, Edward J. Hamad, Danielle E. Herman, John G. Holden, Lily Yan, Katrina Linning-Duffy, Christopher J. Kemp, Joseph R. Patterson, Kathryn M. Miller, Michael Kubik, Nathan Kuhn, Anna C. Stoll, Megan F. Duffy, Kathy Steece-Collier, Allyson Cole-Strauss, Jack W. Lipton, Kelvin C. Luk, Caryl E. Sortwell
Published in Frontiers in Neuroscience (2025-04-01)Get full text
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