Search Results - Colm J. Ryan

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  1. 1

    Paralog dispensability shapes homozygous deletion patterns in tumor genomes by Barbara De Kegel, Colm J Ryan

    Published in Molecular Systems Biology (2023-12-01)
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  2. 2

    Integrative analysis of large-scale loss-of-function screens identifies robust cancer-associated genetic interactions by Christopher J Lord, Niall Quinn, Colm J Ryan

    Published in eLife (2020-05-01)
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  3. 3

    The yeast SR-like protein Npl3 links chromatin modification to mRNA processing. by Erica A Moehle, Colm J Ryan, Nevan J Krogan, Tracy L Kress, Christine Guthrie

    Published in PLoS Genetics (2012-01-01)
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  4. 4

    Cross-species identification of PIP5K1-, splicing- and ubiquitin-related pathways as potential targets for RB1-deficient cells. by Andrey A Parkhitko, Arashdeep Singh, Sharon Hsieh, Yanhui Hu, Richard Binari, Christopher J Lord, Sridhar Hannenhalli, Colm J Ryan, Norbert Perrimon

    Published in PLoS Genetics (2021-02-01)
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  5. 5

    Proteomic compensation by paralogs preserves protein interaction networks after gene loss in cancer by Anjan Venkatesh, Niall Quinn, Swathi Ramachandra Upadhya, Barbara De Kegel, Alfonso Bolado Carrancio, Thomas Lefeivre, Olivier Dennler, Kieran Wynne, Alexander von Kriegsheim, Colm J Ryan

    Published in Molecular Systems Biology (2025-05-01)
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  6. 6

    A compendium of synthetic lethal gene pairs defined by extensive combinatorial pan-cancer CRISPR screening by Victoria Harle, Victoria Offord, Birkan Gökbağ, Lazaros Fotopoulos, Thomas Williams, Diana Alexander, Ishan Mehta, Nicola A. Thompson, Rebeca Olvera-León, Stefan Peidli, Vivek Iyer, Emanuel Gonçalves, Narod Kebabci, Barbara De Kegel, Joris van de Haar, Lang Li, Colm J. Ryan, David J. Adams

    Published in Genome Biology (2025-09-01)
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  7. 7

    ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A by Chris T. Williamson, Rowan Miller, Helen N. Pemberton, Samuel E. Jones, James Campbell, Asha Konde, Nicholas Badham, Rumana Rafiq, Rachel Brough, Aditi Gulati, Colm J. Ryan, Jeff Francis, Peter B. Vermulen, Andrew R. Reynolds, Philip M. Reaper, John R. Pollard, Alan Ashworth, Christopher J. Lord

    Published in Nature Communications (2016-12-01)
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