Search Results - David A Baker

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  1. 1

    CDC50 Orthologues in Plasmodium falciparum Have Distinct Roles in Merozoite Egress and Trophozoite Maturation by Avnish Patel, Stephanie D. Nofal, Michael J. Blackman, David A. Baker

    Published in mBio (2022-08-01)
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  2. 2

    Spatiotemporal and functional characterisation of the Plasmodium falciparum cGMP-dependent protein kinase. by Christine S Hopp, Christian Flueck, Lev Solyakov, Andrew Tobin, David A Baker

    Published in PLoS ONE (2012-01-01)
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  3. 3

    Development of a transgenic Plasmodium berghei line (Pb pfpkg) expressing the P. falciparum cGMP-dependent protein kinase, a novel antimalarial drug target. by Rita Tewari, Eva-Maria Patzewitz, Benoit Poulin, Lindsay Stewart, David A Baker

    Published in PLoS ONE (2014-01-01)
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  4. 4

    Differential IL-18 Dependence of Canonical and Adaptive NK Cells for Antibody Dependent Responses to P. falciparum by Samuel Sherratt, Avnish Patel, David A. Baker, Eleanor M. Riley, Martin R. Goodier

    Published in Frontiers in Immunology (2020-03-01)
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  5. 5

    A model of Notch signalling control of angiogenesis: Evidence of a role for Notch ligand heterodimerization. by Daipeng Chen, Xinxin Liu, Haijiang Wang, Roeland M H Merks, David A Baker

    Published in PLoS Computational Biology (2025-02-01)
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  6. 6

    Targeting the Malaria Parasite cGMP-Dependent Protein Kinase to Develop New Drugs by David A. Baker, Alexios N. Matralis, Simon A. Osborne, Jonathan M. Large, Maria Penzo

    Published in Frontiers in Microbiology (2020-12-01)
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  7. 7

    Malaria parasite cGMP-dependent protein kinase regulates blood stage merozoite secretory organelle discharge and egress. by Christine R Collins, Fiona Hackett, Malcolm Strath, Maria Penzo, Chrislaine Withers-Martinez, David A Baker, Michael J Blackman

    Published in PLoS Pathogens (2013-05-01)
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  8. 8

    Use of a highly specific kinase inhibitor for rapid, simple and precise synchronization of Plasmodium falciparum and Plasmodium knowlesi asexual blood-stage parasites. by Margarida Ressurreição, James A Thomas, Stephanie D Nofal, Christian Flueck, Robert W Moon, David A Baker, Christiaan van Ooij

    Published in PLoS ONE (2020-01-01)
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  9. 9

    Plasmodium falciparum protein phosphatase PP7 is required for early ring-stage development by Avnish Patel, Aline Fréville, Joshua A. Rey, Helen R. Flynn, Konstantinos Koussis, Mark J. Skehel, Michael J. Blackman, David A. Baker

    Published in mBio (2024-11-01)
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  10. 10

    Gametogenesis in malaria parasites is mediated by the cGMP-dependent protein kinase. by Louisa McRobert, Cathy J Taylor, Wensheng Deng, Quinton L Fivelman, Ross M Cummings, Spencer D Polley, Oliver Billker, David A Baker

    Published in PLoS Biology (2008-06-01)
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  11. 11

    A cyclic GMP signalling module that regulates gliding motility in a malaria parasite. by Robert W Moon, Cathy J Taylor, Claudia Bex, Rebecca Schepers, David Goulding, Chris J Janse, Andrew P Waters, David A Baker, Oliver Billker

    Published in PLoS Pathogens (2009-09-01)
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  12. 12

    Expression of the MSPDBL2 antigen in a discrete subset of Plasmodium falciparum schizonts is regulated by GDV1 but may not be linked to sexual commitment by Aline Freville, Lindsay B. Stewart, Kevin K. A. Tetteh, Moritz Treeck, Alfred Cortes, Till S. Voss, Sarah J. Tarr, David A. Baker, David J. Conway

    Published in mBio (2024-05-01)
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  13. 13

    Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites. by Konstantinos Koussis, Silvia Haase, Chrislaine Withers-Martinez, Helen R Flynn, Simone Kunzelmann, Evangelos Christodoulou, Fairouz Ibrahim, Mark Skehel, David A Baker, Michael J Blackman

    Published in PLoS Pathogens (2024-06-01)
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  14. 14

    Crystal structures of the carboxyl cGMP binding domain of the Plasmodium falciparum cGMP-dependent protein kinase reveal a novel capping triad crucial for merozoite egress. by Jeong Joo Kim, Christian Flueck, Eugen Franz, Eduardo Sanabria-Figueroa, Eloise Thompson, Robin Lorenz, Daniela Bertinetti, David A Baker, Friedrich W Herberg, Choel Kim

    Published in PLoS Pathogens (2015-02-01)
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  15. 15

    Epac2 in midbrain dopamine neurons contributes to cocaine reinforcement via enhancement of dopamine release by Xiaojie Liu, Casey R Vickstrom, Hao Yu, Shuai Liu, Shana Terai Snarrenberg, Vladislav Friedman, Lianwei Mu, Bixuan Chen, Thomas J Kelly, David A Baker, Qing-song Liu

    Published in eLife (2022-08-01)
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  16. 16

    Detecting SARS-CoV-2 cryptic lineages using publicly available whole genome wastewater sequencing data. by Reinier Suarez, Devon A Gregory, David A Baker, Clayton A Rushford, Torin L Hunter, Nicholas R Minor, Clayton M Russ, Emma E Copen, David H O'Connor, Marc C Johnson

    Published in PLoS Pathogens (2025-06-01)
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  17. 17

    cAMP-Signalling Regulates Gametocyte-Infected Erythrocyte Deformability Required for Malaria Parasite Transmission. by Ghania Ramdani, Bernina Naissant, Eloise Thompson, Florence Breil, Audrey Lorthiois, Florian Dupuy, Ross Cummings, Yoann Duffier, Yolanda Corbett, Odile Mercereau-Puijalon, Kenneth Vernick, Donatella Taramelli, David A Baker, Gordon Langsley, Catherine Lavazec

    Published in PLoS Pathogens (2015-05-01)
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  18. 18

    Phosphoinositide metabolism links cGMP-dependent protein kinase G to essential Ca²⁺ signals at key decision points in the life cycle of malaria parasites. by Mathieu Brochet, Mark O Collins, Terry K Smith, Eloise Thompson, Sarah Sebastian, Katrin Volkmann, Frank Schwach, Lia Chappell, Ana Rita Gomes, Matthew Berriman, Julian C Rayner, David A Baker, Jyoti Choudhary, Oliver Billker

    Published in PLoS Biology (2014-03-01)
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  19. 19

    Subclinical Infection of Macaques and Baboons with A Baboon Simarterivirus by Connor R. Buechler, Matthew Semler, David A. Baker, Christina Newman, Joseph P. Cornish, Deborah Chavez, Bernadette Guerra, Robert Lanford, Kathy Brasky, Jens H. Kuhn, Reed F. Johnson, David H. O’Connor, Adam L. Bailey

    Published in Viruses (2018-12-01)
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  20. 20

    Cyclic AMP signalling controls key components of malaria parasite host cell invasion machinery. by Avnish Patel, Abigail J Perrin, Helen R Flynn, Claudine Bisson, Chrislaine Withers-Martinez, Moritz Treeck, Christian Flueck, Giuseppe Nicastro, Stephen R Martin, Andres Ramos, Tim W Gilberger, Ambrosius P Snijders, Michael J Blackman, David A Baker

    Published in PLoS Biology (2019-05-01)
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