Search Results - David Brough

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  1. 1

    Obese mice exhibit an altered behavioural and inflammatory response to lipopolysaccharide by Catherine B. Lawrence, David Brough, Elysse M. Knight

    Published in Disease Models & Mechanisms (2012-09-01)
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  2. 2

    Digital interventions for supporting alcohol abstinence in aftercare – a systematic review by Luana Lenzi, Aaliya Ibrahim, David Brough, Alexander Thompson

    Published in Internet Interventions (2025-06-01)
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  3. 3

    Inhibiting the NLRP3 Inflammasome by Lina Y. El-Sharkawy, David Brough, Sally Freeman

    Published in Molecules (2020-11-01)
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  4. 4

    Pyroptosis leads to loss of centrosomal integrity in macrophages by Siyi Bai, Fatima Martin-Sanchez, David Brough, Gloria Lopez-Castejon

    Published in Cell Death Discovery (2024-08-01)
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  5. 5

    Inhibition of calpain blocks the phagosomal escape of Listeria monocytogenes. by Gloria Lopez-Castejon, David Corbett, Marie Goldrick, Ian S Roberts, David Brough

    Published in PLoS ONE (2012-01-01)
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  6. 6

    Plasmodium falciparum-infected erythrocyte co-culture with the monocyte cell line THP-1 does not trigger production of soluble factors reducing brain microvascular barrier function... by Janet Storm, Grazia Camarda, Michael J Haley, David Brough, Kevin N Couper, Alister G Craig

    Published in PLoS ONE (2023-01-01)
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  7. 7

    The NLRP3 inflammasome is essential for IL-18 production in a murine model of macrophage activation syndrome by Tara A. Gleeson, Christina Kaiser, Catherine B. Lawrence, David Brough, Stuart M. Allan, Jack P. Green

    Published in Disease Models & Mechanisms (2024-07-01)
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  8. 8

    Squaramides enhance NLRP3 inflammasome activation by lowering intracellular potassium by Paula I. Seoane, James A. Beswick, Andrew G. Leach, Tessa Swanton, Lucy V. Morris, Kevin Couper, Martin Lowe, Sally Freeman, David Brough

    Published in Cell Death Discovery (2023-12-01)
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  9. 9

    Corrigendum: Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro by Anna Gritsenko, Shi Yu, Fatima Martin-Sanchez, Ines Diaz-del-Olmo, Eva-Maria Nichols, Daniel M. Davis, David Brough, Gloria Lopez-Castejon

    Published in Frontiers in Immunology (2021-09-01)
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  10. 10

    Lymphatic network drainage resolves cerebral edema and facilitates recovery from experimental cerebral malaria by Michael J. Haley, Ruben Barroso, Dhifaf A. Jasim, Megan Haigh, Jack Green, Ben Dickie, Alister G. Craig, David Brough, Kevin N. Couper

    Published in Cell Reports (2024-05-01)
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  11. 11

    Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome by Jack P. Green, Lina Y. El-Sharkawy, Stefan Roth, Jie Zhu, Jiayu Cao, Andrew G. Leach, Arthur Liesz, Sally Freeman, David Brough

    Published in iScience (2023-05-01)
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  12. 12

    Loss of hepatocyte cell division leads to liver inflammation and fibrosis. by Matthew R Dewhurst, Jin Rong Ow, Gözde Zafer, Noémi K M van Hul, Heike Wollmann, Xavier Bisteau, David Brough, Hyungwon Choi, Philipp Kaldis

    Published in PLoS Genetics (2020-11-01)
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  13. 13

    Co-design of a Smartphone App for People Living With Dementia by Applying Agile, Iterative Co-design Principles: Development and Usability Study by Sarah Fox, Laura J E Brown, Steven Antrobus, David Brough, Richard J Drake, Francine Jury, Iracema Leroi, Adrian R Parry-Jones, Matthew Machin

    Published in JMIR mHealth and uHealth (2022-01-01)
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  14. 14

    Author Correction: A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation by Sohaib Nizami, Val Millar, Kanisa Arunasalam, Tryfon Zarganes-Tzitzikas, David Brough, Gary Tresadern, Paul E. Brennan, John B. Davis, Daniel Ebner, Elena Di Daniel

    Published in Scientific Reports (2021-10-01)
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  15. 15

    Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions by Rose Wellens, Victor S. Tapia, Paula I. Seoane, Hayley Bennett, Antony Adamson, Graham Coutts, Jack Rivers-Auty, Martin Lowe, Jack P. Green, Gloria Lopez-Castejon, David Brough, Christopher Hoyle

    Published in Nature Communications (2024-08-01)
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  16. 16

    Evidence That a TRPA1-Mediated Murine Model of Temporomandibular Joint Pain Involves NLRP3 Inflammasome Activation by Xenia Kodji, Zizheng Kee, Robyn McKenna, Joao de Sousa Valente, Harriet Ravenscroft, Hayley McMillan, John Gamble, Yvonne Dombrowski, Paul Moynagh, David Brough, Fionnuala T. Lundy, Susan D. Brain, Ikhlas A. El Karim

    Published in Pharmaceuticals (2021-10-01)
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  17. 17

    Haematopoietic stem cell gene therapy with IL‐1Ra rescues cognitive loss in mucopolysaccharidosis IIIA by Helen Parker, Stuart M Ellison, Rebecca J Holley, Claire O'Leary, Aiyin Liao, Jalal Asadi, Emily Glover, Arunabha Ghosh, Simon Jones, Fiona L Wilkinson, David Brough, Emmanuel Pinteaux, Hervé Boutin, Brian W Bigger

    Published in EMBO Molecular Medicine (2020-02-01)
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  18. 18

    Brazilin is a natural product inhibitor of the NLRP3 inflammasome by Emily McMahon, Sherihan El-Sayed, Jack Green, Christopher Hoyle, Lorna FitzPatrick, Emma V. Jones, Eve Corrie, Rebecca L. Kelly, Mairi Challinor, Sally Freeman, Richard A. Bryce, Catherine B. Lawrence, David Brough, Paul R. Kasher

    Published in iScience (2024-02-01)
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  19. 19

    Cathelicidin is a "fire alarm", generating protective NLRP3-dependent airway epithelial cell inflammatory responses during infection with Pseudomonas aeruginosa. by Brian J McHugh, Rongling Wang, Hsin-Ni Li, Paula E Beaumont, Rebekah Kells, Holly Stevens, Lisa Young, Adriano G Rossi, Robert D Gray, Julia R Dorin, Emily L Gwyer Findlay, David Brough, Donald J Davidson

    Published in PLoS Pathogens (2019-04-01)
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  20. 20

    Spatial mapping of immune cell environments in NF2-related schwannomatosis vestibular schwannoma by Adam P. Jones, Michael J. Haley, Miriam H. Meadows, Grace E. Gregory, Cathal J. Hannan, Ana K. Simmons, Leoma D. Bere, Daniel G. Lewis, Pedro Oliveira, Miriam J. Smith, Andrew T. King, D. Gareth R. Evans, Pawel Paszek, David Brough, Omar N. Pathmanaban, Kevin N. Couper

    Published in Nature Communications (2025-03-01)
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