検索結果 - David M. Ashley

Taking the STING out of radiotherapy: STING checkpoints mediate radiation resistance 著者: Michael C. Brown, Justin T. Low, Michelle L. Bowie, David M. Ashley

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Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma. 著者: Michael A Sun, Haipei Yao, Qing Yang, Christopher J Pirozzi, Vidyalakshmi Chandramohan, David M Ashley, Yiping He

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Gene expression analysis suggests immunosuppressive roles of endolysosomes in glioblastoma 著者: Michael A. Sun, Haipei Yao, Qing Yang, Christopher J. Pirozzi, Vidyalakshmi Chandramohan, David M. Ashley, Yiping He

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Methylation profiling of paediatric pilocytic astrocytoma reveals variants specifically associated with tumour location and predictive of recurrence 著者: Alexandra Sexton‐Oates, Andrew Dodgshun, Volker Hovestadt, David T. W. Jones, David M. Ashley, Michael Sullivan, Duncan MacGregor, Richard Saffery

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The role of chemotherapy in the treatment of central neurocytoma 著者: Margaret O Johnson, John P Kirkpatrick, Mallika P Patel, Annick Desjardins, Dina M Randazzo, Henry S Friedman, David M Ashley, Katherine B Peters

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Understanding and therapeutically exploiting cGAS/STING signaling in glioblastoma 著者: Justin T. Low, Michael C. Brown, Zachary J. Reitman, Joshua D. Bernstock, James M. Markert, Gregory K. Friedman, Matthew S. Waitkus, Michelle L. Bowie, David M. Ashley

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Publisher Correction: Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor‑like population 著者: Joshua A. Regal, María E. Guerra García, Vaibhav Jain, Vidyalakshmi Chandramohan, David M. Ashley, Simon G. Gregory, Eric M. Thompson, Giselle Y. López, Zachary J. Reitman

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cGAS-STING pathway targeted therapies and their applications in the treatment of high-grade glioma [version 1; peer review: 3 approved] 著者: Amy B Heimberger, David M Ashley, Charles David James, Alexander H Stegh, Michael A Curran, Peng Zhang, Justin T Low, Hinda Najem, Akanksha Sanjay Mahajan, Shashwat Tripathi

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Ganglioglioma deep transcriptomics reveals primitive neuroectoderm neural precursor-like population 著者: Joshua A. Regal, María E. Guerra García, Vaibhav Jain, Vidyalakshmi Chandramohan, David M. Ashley, Simon G. Gregory, Eric M. Thompson, Giselle Y. López, Zachary J. Reitman

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Spatial transcriptomics reveals segregation of tumor cell states in glioblastoma and marked immunosuppression within the perinecrotic niche 著者: Mengyi Liu, Zhicheng Ji, Vaibhav Jain, Vanessa L. Smith, Emily Hocke, Anoop P. Patel, Roger E. McLendon, David M. Ashley, Simon G. Gregory, Giselle Y. López

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Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors. 著者: Elizabeth M Algar, Andrea Muscat, Vinod Dagar, Christian Rickert, C W Chow, Jaclyn A Biegel, Paul G Ekert, Richard Saffery, Jeff Craig, Ricky W Johnstone, David M Ashley

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Intratumor childhood vaccine-specific CD4+ T-cell recall coordinates antitumor CD8+ T cells and eosinophils 著者: Daniel Landi, Annick Desjardins, Matthias Gromeier, Darell D Bigner, Smita K Nair, Michael C Brown, Georgia M Beasley, David M Ashley, Yuanfan Yang, Zachary P McKay, Dina M Randazzo

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Primary brain tumor patients admitted to a US intensive care unit: a descriptive analysis 著者: Jennifer H Kang, Christa B Swisher, Evan D Buckley, James E Herndon, Eric S Lipp, John P Kirkpatrick, Annick Desjardins, Henry S Friedman, Margaret O Johnson, Dina M Randazzo, David M Ashley, Katherine B Peters

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Neuronal CaMKK2 promotes immunosuppression and checkpoint blockade resistance in glioblastoma 著者: William H. Tomaszewski, Jessica Waibl-Polania, Molly Chakraborty, Jonathan Perera, Jeremy Ratiu, Alexandra Miggelbrink, Donald P. McDonnell, Mustafa Khasraw, David M. Ashley, Peter E. Fecci, Luigi Racioppi, Luis Sanchez-Perez, Michael D. Gunn, John H. Sampson

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Systematic review of combinations of targeted or immunotherapy in advanced solid tumors 著者: Mustafa Khasraw, Susan M Chang, Amy B Heimberger, Michael Lim, John Simes, Solmaz Sahebjam, Michael Platten, Wolfgang Wick, David M Ashley, Patrick Y Wen, Aaron C Tan, Stephen J Bagley, Howard Colman, Evanthia Galanis, Alireza Mansouri, Simon Khagi, Minesh P Mehta, Vinay K Puduvalli, Scott J Antonia, Don Berry

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Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas 著者: Seethalakshmi Hariharan, Benjamin T. Whitfield, Christopher J. Pirozzi, Matthew S. Waitkus, Michael C. Brown, Michelle L. Bowie, David M. Irvin, Kristen Roso, Rebecca Fuller, Janell Hostettler, Sharvari Dharmaiah, Emiley A. Gibson, Aaron Briley, Avani Mangoli, Casey Fraley, Mariah Shobande, Kevin Stevenson, Gao Zhang, Prit Benny Malgulwar, Hannah Roberts, Martin Roskoski, Ivan Spasojevic, Stephen T. Keir, Yiping He, Maria G. Castro, Jason T. Huse, David M. Ashley

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STING agonist 8803 reprograms the immune microenvironment and increases survival in preclinical models of glioblastoma 著者: Hinda Najem, Spencer T. Lea, Shashwat Tripathi, Lisa Hurley, Chao-Hsien Chen, Ivana William, Moloud Sooreshjani, Michelle Bowie, Genevieve Hartley, Corey Dussold, Sebastian Pacheco, Crismita Dmello, Catalina Lee-Chang, Kathleen McCortney, Alicia Steffens, Jordain Walshon, Martina Ott, Jun Wei, Anantha Marisetty, Irina Balyasnikova, Roger Stupp, Rimas V. Lukas, Jian Hu, Charles David James, Craig M. Horbinski, Maciej S. Lesniak, David M. Ashley, Waldemar Priebe, Leonidas C. Platanias, Michael A. Curran, Amy B. Heimberger

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Disruption of ataxia telangiectasia–mutated kinase enhances radiation therapy efficacy in spatially directed diffuse midline glioma models 著者: Avani Mangoli, Vennesa Valentine, Spencer M. Maingi, Sophie R. Wu, Harrison Q. Liu, Michael Aksu, Vaibhav Jain, Bronwen E. Foreman, Joshua A. Regal, Loren B. Weidenhammer, Connor E. Stewart, Maria E. Guerra Garcia, Emily Hocke, Karen Abramson, Tal Falick Michaeli, Nerissa T. Williams, Lixia Luo, Megan Romero, Katherine Deland, Samantha Gadd, Eita Uchida, Laura Attardi, Kouki Abe, Rintaro Hashizume, David M. Ashley, Oren J. Becher, David G. Kirsch, Simon G. Gregory, Zachary J. Reitman

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A real-world observation of patients with glioblastoma treated with a personalized peptide vaccine 著者: Pauline Latzer, Henning Zelba, Florian Battke, Annekathrin Reinhardt, Borong Shao, Oliver Bartsch, Armin Rabsteyn, Johannes Harter, Martin Schulze, Thomas Okech, Alexander Golf, Christina Kyzirakos-Feger, Simone Kayser, Natalia Pieper, Magdalena Feldhahn, Julian Wünsche, Christian Seitz, Dirk Hadaschik, Claus Garbe, Till-Karsten Hauser, Christian la Fougère, Dirk Biskup, Dawn Brooke, David Parker, Uwe M. Martens, Gerald Illerhaus, Deborah T. Blumenthal, Ryan Merrell, Luisa Sánchez Lorenzo, Máté Hidvégi, Paula de Robles, Sied Kebir, William W. Li, Vincent W. Li, Matthew Williams, Alexandra M. Miller, Santosh Kesari, Michael Castro, Annick Desjardins, David M. Ashley, Henry S. Friedman, Patrick Y. Wen, Elisabeth C. Neil, Fabio M. Iwamoto, Bence Sipos, Karsten Geletneky, Lars Zender, Martin Glas, David A. Reardon, Saskia Biskup

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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma 著者: Ryan J. Duchatel, Evangeline R. Jackson, Sarah G. Parackal, Dylan Kiltschewskij, Izac J. Findlay, Abdul Mannan, Dilana E. Staudt, Bryce C. Thomas, Zacary P. Germon, Sandra Laternser, Padraic S. Kearney, M. Fairuz B. Jamaluddin, Alicia M. Douglas, Tyrone Beitaki, Holly P. McEwen, Mika L. Persson, Emily A. Hocke, Vaibhav Jain, Michael Aksu, Elizabeth E. Manning, Heather C. Murray, Nicole M. Verrills, Claire Xin Sun, Paul Daniel, Ricardo E. Vilain, David A. Skerrett-Byrne, Brett Nixon, Susan Hua, Charles E. de Bock, Yolanda Colino-Sanguino, Fatima Valdes-Mora, Maria Tsoli, David S. Ziegler, Murray J. Cairns, Eric H. Raabe, Nicholas A. Vitanza, Esther Hulleman, Timothy N. Phoenix, Carl Koschmann, Frank Alvaro, Christopher V. Dayas, Christopher L. Tinkle, Helen Wheeler, James R. Whittle, David D. Eisenstat, Ron Firestein, Sabine Mueller, Santosh Valvi, Jordan R. Hansford, David M. Ashley, Simon G. Gregory, Lindsay B. Kilburn, Javad Nazarian, Jason E. Cain, Matthew D. Dun

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