Search Results - David Sumpton

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  1. 1

    Pyruvate transamination and NAD biosynthesis enable proliferation of succinate dehydrogenase-deficient cells by supporting aerobic glycolysis by Luisa Ricci, Federico Uchenna Stanley, Tanja Eberhart, Francesco Mainini, David Sumpton, Simone Cardaci

    Published in Cell Death and Disease (2023-07-01)
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  2. 2

    A Novel Pyrazolopyrimidine Ligand of Human PGK1 and Stress Sensor DJ1 Modulates the Shelterin Complex and Telomere Length Regulation by Alan E. Bilsland, Yu Liu, Andrew Turnbull, David Sumpton, Katrina Stevenson, Claire J. Cairney, Susan M. Boyd, Jon Roffey, David Jenkinson, W. Nicol Keith

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  3. 3

    Inhibition of mitochondrial folate metabolism drives differentiation through mTORC1 mediated purine sensing by Martha M. Zarou, Kevin M. Rattigan, Daniele Sarnello, Engy Shokry, Amy Dawson, Angela Ianniciello, Karen Dunn, Mhairi Copland, David Sumpton, Alexei Vazquez, G. Vignir Helgason

    Published in Nature Communications (2024-03-01)
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  4. 4

    Stratification of cancer and diabetes based on circulating levels of formate and glucose by Matthias Pietzke, Salvador Fernandez Arroyo, David Sumpton, Gillian M. Mackay, Begoña Martin-Castillo, Jordi Camps, Jorge Joven, Javier A. Menendez, Alexei Vazquez, On behalf of the METTEN study group

    Published in Cancer & Metabolism (2019-04-01)
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  5. 5

    Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis by Giuseppe Taurino, Ruhi Deshmukh, Victor H. Villar, Martina Chiu, Robin Shaw, Ann Hedley, Engy Shokry, David Sumpton, Erica Dander, Giovanna D'Amico, Ovidio Bussolati, Saverio Tardito

    Published in Molecular Metabolism (2022-09-01)
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  6. 6

    Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis by Tobias Ackermann, Engy Shokry, Ruhi Deshmukh, Jayanthi Anand, Laura C A Galbraith, Louise Mitchell, Giovanny Rodriguez-Blanco, Victor H Villar, Britt Amber Sterken, Colin Nixon, Sara Zanivan, Karen Blyth, David Sumpton, Saverio Tardito

    Published in EMBO Molecular Medicine (2024-10-01)
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  7. 7

    ACOD1 deficiency offers protection in a mouse model of diet-induced obesity by maintaining a healthy gut microbiota by Tanja Eberhart, Federico Uchenna Stanley, Luisa Ricci, Tiziana Chirico, Roberto Ferrarese, Sofia Sisti, Alessandra Scagliola, Andreina Baj, Sylvia Badurek, Andreas Sommer, Rachel Culp-Hill, Monika Dzieciatkowska, Engy Shokry, David Sumpton, Angelo D’Alessandro, Nicola Clementi, Nicasio Mancini, Simone Cardaci

    Published in Cell Death and Disease (2024-02-01)
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  8. 8

    PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle by Mohaned Benzarti, Laura Neises, Anais Oudin, Christina Krötz, Elodie Viry, Ernesto Gargiulo, Coralie Pulido, Maryse Schmoetten, Vitaly Pozdeev, Nadia I. Lorenz, Michael W. Ronellenfitsch, David Sumpton, Marc Warmoes, Christian Jaeger, Antoine Lesur, Björn Becker, Etienne Moussay, Jerome Paggetti, Simone P. Niclou, Elisabeth Letellier, Johannes Meiser

    Published in Cell Reports (2024-03-01)
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  9. 9

    Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells by Kevin M. Rattigan, Zuzana Brabcova, Daniele Sarnello, Martha M. Zarou, Kiron Roy, Ryan Kwan, Lucie de Beauchamp, Amy Dawson, Angela Ianniciello, Ahmed Khalaf, Eric R. Kalkman, Mary T. Scott, Karen Dunn, David Sumpton, Alison M. Michie, Mhairi Copland, Saverio Tardito, Eyal Gottlieb, G. Vignir Helgason

    Published in Nature Communications (2023-08-01)
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  10. 10

    THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer by Arnaud Blomme, Coralie Peter, Ernest Mui, Giovanny Rodriguez Blanco, Ning An, Louise M Mason, Lauren E Jamieson, Grace H McGregor, Sergio Lilla, Chara Ntala, Rachana Patel, Marc Thiry, Sonia H Y Kung, Marine Leclercq, Catriona A Ford, Linda K Rushworth, David J McGarry, Susan Mason, Peter Repiscak, Colin Nixon, Mark J Salji, Elke Markert, Gillian M MacKay, Jurre J Kamphorst, Duncan Graham, Karen Faulds, Ladan Fazli, Martin E Gleave, Edward Avezov, Joanne Edwards, Huabing Yin, David Sumpton, Karen Blyth, Pierre Close, Daniel J Murphy, Sara Zanivan, Hing Y Leung

    Published in EMBO Molecular Medicine (2022-01-01)
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