نتائج البحث - David T. Breault

Distinct Processes and Transcriptional Targets Underlie CDX2 Requirements in Intestinal Stem Cells and Differentiated Villus Cells حسب Adrianna K. San Roman, Alessio Tovaglieri, David T. Breault, Ramesh A. Shivdasani

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Direct therapeutic effect of sulfadoxine-pyrimethamine on nutritional deficiency-induced enteric dysfunction in a human Intestine ChipResearch in context حسب Seongmin Kim, Arash Naziripour, Pranav Prabhala, Viktor Horváth, Abidemi Junaid, David T. Breault, Girija Goyal, Donald E. Ingber

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Calcineurin regulates aldosterone production via dephosphorylation of NFATC4 حسب Mesut Berber, Sining Leng, Agnieszka Wengi, Denise V. Winter, Alex Odermatt, Felix Beuschlein, Johannes Loffing, David T. Breault, David Penton

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JAK/STAT-1 Signaling Is Required for Reserve Intestinal Stem Cell Activation during Intestinal Regeneration Following Acute Inflammation حسب Camilla A. Richmond, Hannah Rickner, Manasvi S. Shah, Tracy Ediger, Luke Deary, Fanny Zhou, Alessio Tovaglieri, Diana L. Carlone, David T. Breault

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Loss of WNT2B Increases Tumor Burden and Malignant Features in Colorectal Cancer حسب Luiz Fernando Silva Oliveira, Yu-Syuan Wu, Sathuwarman Raveenthiraraj, Jaedeok Kwon, Venkata S. Dasuri, Comfort Adegboye, Juan Putra, Jorge O. Munera, Diana L. Carlone, David T. Breault, Amy E. O’Connell

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The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile. حسب Jesse Lyons, Phaedra C Ghazi, Alina Starchenko, Alessio Tovaglieri, Katherine R Baldwin, Emily J Poulin, Jessica J Gierut, Casie Genetti, Vijay Yajnik, David T Breault, Douglas A Lauffenburger, Kevin M Haigis

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An immune-competent human gut microphysiological system enables inflammation-modulation by Faecalibacterium prausnitzii حسب Jianbo Zhang, Yu-Ja Huang, Martin Trapecar, Charles Wright, Kirsten Schneider, John Kemmitt, Victor Hernandez-Gordillo, Jun Young Yoon, Mathilde Poyet, Eric J. Alm, David T. Breault, David L. Trumper, Linda G. Griffith

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Robust differentiation of human enteroendocrine cells from intestinal stem cells حسب Daniel Zeve, Eric Stas, Joshua de Sousa Casal, Prabhath Mannam, Wanshu Qi, Xiaolei Yin, Sarah Dubois, Manasvi S. Shah, Erin P. Syverson, Sophie Hafner, Jeffrey M. Karp, Diana L. Carlone, Jose Ordovas-Montanes, David T. Breault

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Species-specific enhancement of enterohemorrhagic E. coli pathogenesis mediated by microbiome metabolites حسب Alessio Tovaglieri, Alexandra Sontheimer-Phelps, Annelies Geirnaert, Rachelle Prantil-Baun, Diogo M. Camacho, David B. Chou, Sasan Jalili-Firoozinezhad, Tomás de Wouters, Magdalena Kasendra, Michael Super, Mark J. Cartwright, Camilla A. Richmond, David T. Breault, Christophe Lacroix, Donald E. Ingber

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Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants حسب Songhai Tian, Xiaozhe Xiong, Ji Zeng, Siyu Wang, Benjamin Jean-Marie Tremblay, Peng Chen, Baohua Chen, Min Liu, Pengsheng Chen, Kuanwei Sheng, Daniel Zeve, Wanshu Qi, David T. Breault, César Rodríguez, Ralf Gerhard, Rongsheng Jin, Andrew C. Doxey, Min Dong

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The transcription factor HHEX maintains glucocorticoid levels and protects adrenals from androgen-induced lipid depletion حسب Typhanie Dumontet, Kaitlin J. Basham, Micah C. Foster, Emma Silverman, Kyle A. Heard, Dominque Johnson, Chaelin Lee, Samuel W. Plaska, David T. Breault, David Penton, Felix Beuschlein, Adina F. Turcu, Christopher R. LaPensee, Antonio Marcondes Lerario, Gary D. Hammer

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Generation of glucocorticoid-producing cells derived from human pluripotent stem cells حسب Gerard Ruiz-Babot, Ariane Eceiza, Fernando Abollo-Jiménez, Maria Malyukov, Diana L. Carlone, Kleiton Borges, Alexandra Rodrigues Da Costa, Shamma Qarin, Takuya Matsumoto, Ryuji Morizane, William C. Skarnes, Barbara Ludwig, Paul J. Chapple, Leonardo Guasti, Helen L. Storr, Stefan R. Bornstein, David T. Breault

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WNT2B Deficiency Causes Enhanced Susceptibility to Colitis Due to Increased Inflammatory Cytokine ProductionSummary حسب Amy E. O’Connell, Sathuwarman Raveenthiraraj, Luiz Fernando Silva Oliveira, Comfort Adegboye, Venkata Siva Dasuri, Wanshu Qi, Radhika S. Khetani, Akaljot Singh, Nambirajam Sundaram, Jasmine Lin, Prathima Nandivada, Lorena Rincón-Cruz, Jeffrey D. Goldsmith, Jay R. Thiagarajah, Diana L. Carlone, Jerrold R. Turner, Pankaj B. Agrawal, Michael Helmrath, David T. Breault

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Glucocorticoids induce a phagocytic C1Q+ macrophage phenotype primed for IFNγ-dependent CXCL9 secretion حسب Alexandra S. Triebig, Tanja Maier, Paul Schwarzlmueller, Sena Atici, Martin E. Kirmaier, Vasileios Chortis, Kleiton S. Borges, David T. Breault, Claudio Ribeiro, Adrian Gottschlich, Laura-Sophie Landwehr, Nicole Bechmann, Mirko Peitzsch, Nagarajan Paramasivam, Sebastian Theurich, Stefan Fröhling, Hanno Glimm, Daniel Hübschmann, Martin Fassnacht, Martin Reincke, Jose Pedro Friedmann-Angeli, Isabel Weigand, Matthias Kroiss

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Dlk1 is a novel adrenocortical stem/progenitor cell marker that predicts malignancy in adrenocortical carcinoma حسب Katia Mariniello, James F. H. Pittaway, Barbara Altieri, Kleiton Silva Borges, Irene Hadjidemetriou, Claudio Ribeiro, Gerard Ruiz‐Babot, David S. Tourigny, Jiang A. Lim, Julie Foster, Julie Cleaver, Jane Sosabowski, Nafis Rahman, Milena Doroszko, Constanze Hantel, Sandra Sigala, Andrea Abate, Mariangela Tamburello, Katja Kiseljak‐Vassiliades, Margaret Wierman, Charlotte Hall, Laila Parvanta, Tarek E. Abdel‐Aziz, Teng‐Teng Chung, Aimee Di Marco, Fausto Palazzo, Celso E. Gomez‐Sanchez, David R. Taylor, Oliver Rayner, Cristina L. Ronchi, Carles Gaston‐Massuet, Silviu Sbiera, William M. Drake, Emanuel Rognoni, Matthias Kroiss, David T. Breault, Martin Fassnacht, Leonardo Guasti

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