Search Results - David Tweedie
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Cognitive impairments accompanying rodent mild traumatic brain injury involve p53-dependent neuronal cell death and are ameliorated by the tetrahydrobenzothiazole PFT-α. by Lital Rachmany, David Tweedie, Vardit Rubovitch, Qian-Sheng Yu, Yazhou Li, Jia-Yi Wang, Chaim G Pick, Nigel H Greig
Published in PLoS ONE (2013-01-01)Get full text
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Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury by David Tweedie, Hanuma Kumar Karnati, Roger Mullins, Chaim G Pick, Barry J Hoffer, Edward J Goetzl, Dimitrios Kapogiannis, Nigel H Greig
Published in eLife (2020-08-01)Get full text
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A New Generation of IMiDs as Treatments for Neuroinflammatory and Neurodegenerative Disorders by Katherine O. Kopp, Margaret E. Greer, Elliot J. Glotfelty, Shih-Chang Hsueh, David Tweedie, Dong Seok Kim, Marcella Reale, Neil Vargesson, Nigel H. Greig
Published in Biomolecules (2023-04-01)Get full text
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Pomalidomide Improves Motor Behavioral Deficits and Protects Cerebral Cortex and Striatum Against Neurodegeneration Through a Reduction of Oxidative/Nitrosative Damages and Neuroin... by Ya-Ni Huang, Nigel H. Greig, Pen-Sen Huang, Yung-Hsiao Chiang, Alan Hoffer, Chih-Hao Yang, David Tweedie, Ying Chen, Ju-Chi Ou, Jia-Yi Wang
Published in Cell Transplantation (2024-03-01)Get full text
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The RhoA-ROCK1/ROCK2 Pathway Exacerbates Inflammatory Signaling in Immortalized and Primary Microglia by Elliot J. Glotfelty, Luis B. Tovar-y-Romo, Shih-Chang Hsueh, David Tweedie, Yazhou Li, Brandon K. Harvey, Barry J. Hoffer, Tobias E. Karlsson, Lars Olson, Nigel H. Greig
Published in Cells (2023-05-01)Get full text
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(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice by Daniela Lecca, Miaad Bader, David Tweedie, Alexander F. Hoffman, Yoo Jin Jung, Shin-Chang Hsueh, Barry J. Hoffer, Robert E. Becker, Chaim G. Pick, Carl R. Lupica, Nigel H. Greig
Published in Neurobiology of Disease (2019-10-01)Get full text
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Activity of a Novel Anti-Inflammatory Agent F-3,6′-dithiopomalidomide as a Treatment for Traumatic Brain Injury by Shih Chang Hsueh, Michael T. Scerba, David Tweedie, Daniela Lecca, Dong Seok Kim, Abdul Mannan Baig, Yu Kyung Kim, Inho Hwang, Sun Kim, Warren R. Selman, Barry J. Hoffer, Nigel H. Greig
Published in Biomedicines (2022-09-01)Get full text
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Corrigendum to “Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury” [Neurobiology of Disease Volume... by Miaad Bader, Yazhou Li, Daniela Lecca, Vardit Rubovitch, David Tweedie, Elliot Glotfelty, Lital Rachmany, Hee Kyung Kim, Ho-Il Choi, Barry J. Hoffer, Chaim G. Pick, Nigel H. Greig, Dong Seok Kim
Published in Neurobiology of Disease (2024-09-01)Get full text
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Antiangiogenic Activity and in Silico Cereblon Binding Analysis of Novel Thalidomide Analogs by Megan L. Peach, Shaunna L. Beedie, Cindy H. Chau, Matthew K. Collins, Suzana Markolovic, Weiming Luo, David Tweedie, Christian Steinebach, Nigel H. Greig, Michael Gütschow, Neil Vargesson, Marc C. Nicklaus, William D. Figg
Published in Molecules (2020-12-01)Get full text
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Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury by Daniela Lecca, Shih-Chang Hsueh, Weiming Luo, David Tweedie, Dong Seok Kim, Abdul Mannan Baig, Neil Vargesson, Yu Kyung Kim, Inho Hwang, Sun Kim, Barry J. Hoffer, Yung-Hsiao Chiang, Nigel H. Greig
Published in Journal of Biomedical Science (2023-03-01)Get full text
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3,6’-dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation by Chih-Tung Lin, Daniela Lecca, Ling-Yu Yang, Weiming Luo, Michael T Scerba, David Tweedie, Pen-Sen Huang, Yoo-Jin Jung, Dong Seok Kim, Chih-Hao Yang, Barry J Hoffer, Jia-Yi Wang, Nigel H Greig
Published in eLife (2020-06-01)Get full text
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Pomalidomide Reduces Ischemic Brain Injury in Rodents by Yan-Rou Tsai, David Tweedie, Ignacio Navas-Enamorado, Michael T. Scerba, Cheng-Fu Chang, Jing-Huei Lai, John Chung-Che Wu, Yen-Hua Chen, Shuo-Jhen Kang, Barry J. Hoffer, Rafael de Cabo, Nigel H. Greig, Yung-Hsiao Chiang, Kai-Yun Chen
Published in Cell Transplantation (2019-04-01)Get full text
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Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanism... by David Tweedie, Koji Fukui, Yazhou Li, Qian-Sheng Yu, Shani Barak, Ian A Tamargo, Vardit Rubovitch, Harold W Holloway, Elin Lehrmann, William H Wood, Yongqing Zhang, Kevin G Becker, Evelyn Perez, Henriette Van Praag, Yu Luo, Barry J Hoffer, Robert E Becker, Chaim G Pick, Nigel H Greig
Published in PLoS ONE (2016-01-01)Get full text
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Targeting neuroinflammation: 3-monothiopomalidomide a new drug candidate to mitigate traumatic brain injury and neurodegeneration by Shih Chang Hsueh, Pathik Parekh, Buyandelger Batsaikhan, Neil Vargesson, David Tweedie, Weiming Luo, Chirag N. Patel, Dong Liu, Ross A. McDevitt, Abdul Mannan Baig, Yu Kyung Kim, Sun Kim, Inho Hwang, Juwan Kim, Mee Youn Lee, Anna R. Carta, Warren R. Selman, Barry J. Hoffer, Dong Seok Kim, Nigel H. Greig
Published in Journal of Biomedical Science (2025-06-01)Get full text
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3,6′- and 1,6′-Dithiopomalidomide Mitigate Ischemic Stroke in Rats and Blunt Inflammation by Yan-Rou Tsai, Dong Seok Kim, Shih-Chang Hsueh, Kai-Yun Chen, John Chung-Che Wu, Jia-Yi Wang, Yi-Syue Tsou, Inho Hwang, Yukyung Kim, Dayeon Gil, Eui Jung Jo, Baek-Soo Han, David Tweedie, Daniela Lecca, Michael T. Scerba, Warren R. Selman, Barry J. Hoffer, Nigel H. Greig, Yung-Hsiao Chiang
Published in Pharmaceutics (2022-04-01)Get full text
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