نتائج البحث - Dirk Schnappinger

Synthetic lethality of Mycobacterium tuberculosis NADH dehydrogenases is due to impaired NADH oxidation حسب Yuanyuan Xu, Sabine Ehrt, Dirk Schnappinger, Tiago Beites

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Interruption of mycothiol synthesis and intracellular redox status impact iron-regulated reporter activation in Mycobacterium smegmatis حسب Alexandra H. Miller, Frances Marks, Luming Chan, Helene Botella, Dirk Schnappinger, Sabine Ehrt

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A dose-response model for statistical analysis of chemical genetic interactions in CRISPRi screens. حسب Sanjeevani Choudhery, Michael A DeJesus, Aarthi Srinivasan, Jeremy Rock, Dirk Schnappinger, Thomas R Ioerger

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CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis حسب Steven J. Grigsby, G.V.R. Krishna Prasad, Joshua B. Wallach, Ekansh Mittal, Fong-Fu Hsu, Dirk Schnappinger, Jennifer A. Philips

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CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis حسب Steven J. Grigsby, G.V.R. Krishna Prasad, Joshua B. Wallach, Ekansh Mittal, Fong-Fu Hsu, Dirk Schnappinger, Jennifer A. Philips

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Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression. حسب Sae Woong Park, Marcus Klotzsche, Daniel J Wilson, Helena I Boshoff, Hyungjin Eoh, Ujjini Manjunatha, Antje Blumenthal, Kyu Rhee, Clifton E Barry, Courtney C Aldrich, Sabine Ehrt, Dirk Schnappinger

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Mycobacterial biotin synthases require an auxiliary protein to convert dethiobiotin into biotin حسب Di Qu, Peng Ge, Laure Botella, Sae Woong Park, Ha-Na Lee, Natalie Thornton, James M. Bean, Inna V. Krieger, James C. Sacchettini, Sabine Ehrt, Courtney C. Aldrich, Dirk Schnappinger

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Metabolically distinct roles of NAD synthetase and NAD kinase define the essentiality of NAD and NADP in Mycobacterium tuberculosis حسب Ritu Sharma, Travis E. Hartman, Tiago Beites, Jee-Hyun Kim, Hyungjin Eoh, Curtis A. Engelhart, Linnan Zhu, Daniel J. Wilson, Courtney C. Aldrich, Sabine Ehrt, Kyu Young Rhee, Dirk Schnappinger

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Cyclic AMP is a critical mediator of intrinsic drug resistance and fatty acid metabolism in M. tuberculosis حسب Andrew I Wong, Tiago Beites, Kyle A Planck, Rachael A Fieweger, Kathryn A Eckartt, Shuqi Li, Nicholas C Poulton, Brian C VanderVen, Kyu Y Rhee, Dirk Schnappinger, Sabine Ehrt, Jeremy Rock

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Mycobacterium tuberculosis exploits asparagine to assimilate nitrogen and resist acid stress during infection. حسب Alexandre Gouzy, Gérald Larrouy-Maumus, Daria Bottai, Florence Levillain, Alexia Dumas, Joshua B Wallach, Irène Caire-Brandli, Chantal de Chastellier, Ting-Di Wu, Renaud Poincloux, Roland Brosch, Jean-Luc Guerquin-Kern, Dirk Schnappinger, Luiz Pedro Sório de Carvalho, Yannick Poquet, Olivier Neyrolles

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Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis حسب Bei Shi Lee, Kiel Hards, Curtis A Engelhart, Erik J Hasenoehrl, Nitin P Kalia, Jared S Mackenzie, Ekaterina Sviriaeva, Shi Min Sherilyn Chong, Malathy Sony S Manimekalai, Vanessa H Koh, John Chan, Jiayong Xu, Sylvie Alonso, Marvin J Miller, Adrie J C Steyn, Gerhard Grüber, Dirk Schnappinger, Michael Berney, Gregory M Cook, Garrett C Moraski, Kevin Pethe

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Spirocycle MmpL3 Inhibitors with Improved hERG and Cytotoxicity Profiles as Inhibitors of Mycobacterium tuberculosis Growth حسب Peter C. Ray, Margaret Huggett, Penelope A. Turner, Malcolm Taylor, Laura A. T. Cleghorn, Julie Early, Anuradha Kumar, Shilah A. Bonnett, Lindsay Flint, Douglas Joerss, James Johnson, Aaron Korkegian, Steven Mullen, Abraham L. Moure, Susan H. Davis, Dinakaran Murugesan, Michael Mathieson, Nicola Caldwell, Curtis A. Engelhart, Dirk Schnappinger, Ola Epemolu, Fabio Zuccotto, Jennifer Riley, Paul Scullion, Laste Stojanovski, Lisa Massoudi, Gregory T. Robertson, Anne J. Lenaerts, Gail Freiberg, Dale J. Kempf, Thierry Masquelin, Philip A. Hipskind, Joshua Odingo, Kevin D. Read, Simon R. Green, Paul G. Wyatt, Tanya Parish

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