Search Results - Frank M Longo
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Small molecule modulation of p75NTR engages the autophagy-lysosomal pathway and reduces huntingtin aggregates in cellular and mouse models of Huntington's disease by Danielle A. Simmons, Namitha Alexander, Gloria Cao, Ido Rippin, Yarine Lugassy, Hagit Eldar-Finkelman, Frank M. Longo
Published in Neurotherapeutics (2025-03-01)Get full text
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A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice by Destynie Medeiros, Karen Ayala-Baylon, Hailey Egido-Betancourt, Eric Miller, Christopher Chapleau, Holly Robinson, Mary L. Phillips, Tao Yang, Frank M. Longo, Wei Li, Lucas Pozzo-Miller
Published in Disease Models & Mechanisms (2024-06-01)Get full text
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Human striatal progenitor cells that contain inducible safeguards and overexpress BDNF rescue Huntington’s disease phenotypes by Danielle A. Simmons, Sridhar Selvaraj, Tingshuo Chen, Gloria Cao, Talita Souto Camelo, Tyne L.M. McHugh, Selena Gonzalez, Renata M. Martin, Juste Simanauskaite, Nobuko Uchida, Matthew H. Porteus, Frank M. Longo
Published in Molecular Therapy: Methods & Clinical Development (2025-03-01)Get full text
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Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment. by Tao Yang, Juliet K Knowles, Qun Lu, Hong Zhang, Ottavio Arancio, Laura A Moore, Timothy Chang, Qian Wang, Katrin Andreasson, Jayakumar Rajadas, Gerald G Fuller, Youmei Xie, Stephen M Massa, Frank M Longo
Published in PLoS ONE (2008-01-01)Get full text
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Genetic and multi‐omic risk assessment of Alzheimer's disease implicates core associated biological domains by Gregory A. Cary, Jesse C. Wiley, Jake Gockley, Stephen Keegan, Sai Sruthi Amirtha Ganesh, Laura Heath, Robert R. Butler III, Lara M. Mangravite, Benjamin A. Logsdon, Frank M. Longo, Allan Levey, Anna K. Greenwood, Gregory W. Carter
Published in Alzheimer’s & Dementia: Translational Research & Clinical Interventions (2024-04-01)Get full text
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Open drug discovery in Alzheimer's disease by Alison D. Axtman, Paul E. Brennan, Tristan Frappier‐Brinton, Ranjita Betarbet, Gregory W. Carter, Haian Fu, Opher Gileadi, Anna K. Greenwood, Karina Leal, Frank M. Longo, Lara M. Mangravite, Aled M. Edwards, Allan I. Levey, The Emory‐Sage‐SGC TREAT‐AD Center
Published in Alzheimer’s & Dementia: Translational Research & Clinical Interventions (2023-04-01)Get full text
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Parkinson’s disease is characterized by vitamin B6-dependent inflammatory kynurenine pathway dysfunction by Edward N. Wilson, Jacob Umans, Michelle S. Swarovski, Paras S. Minhas, Justin H. Mendiola, Øivind Midttun, Arve Ulvik, Marian Shahid-Besanti, Patricia Linortner, Siddhita D. Mhatre, Qian Wang, Divya Channappa, Nicole K. Corso, Lu Tian, Carolyn A. Fredericks, Geoffrey A. Kerchner, Edward D. Plowey, Brenna Cholerton, Per M. Ueland, Cyrus P. Zabetian, Nora E. Gray, Joseph F. Quinn, Thomas J. Montine, Sharon J. Sha, Frank M. Longo, David A. Wolk, Alice Chen-Plotkin, Victor W. Henderson, Tony Wyss-Coray, Anthony D. Wagner, Elizabeth C. Mormino, Nima Aghaeepour, Kathleen L. Poston, Katrin I. Andreasson
Published in npj Parkinson's Disease (2025-04-01)Get full text
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