Search Results - Hartmut Jaeschke
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Role of Pyroptosis in Acetaminophen-Induced Hepatotoxicity by Hartmut Jaeschke, David S. Umbaugh, Anup Ramachandran
Published in Livers (2022-12-01)Get full text
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Mitochondrial Dynamics in Drug-Induced Liver Injury by Anup Ramachandran, David S. Umbaugh, Hartmut Jaeschke
Published in Livers (2021-06-01)Get full text
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Translocation of Adenosine A2B Receptor to Mitochondria Influences Cytochrome P450 2E1 Activity after Acetaminophen Overdose by Giselle Sanchez-Guerrero, David S. Umbaugh, Abhay A. Ramachandran, Antonio Artigues, Hartmut Jaeschke, Anup Ramachandran
Published in Livers (2023-12-01)Get full text
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Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfalls by Hartmut Jaeschke, Olamide B. Adelusi, Jephte Y. Akakpo, Nga T. Nguyen, Giselle Sanchez-Guerrero, David S. Umbaugh, Wen-Xing Ding, Anup Ramachandran
Published in Acta Pharmaceutica Sinica B (2021-12-01)Get full text
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Contrasting model mechanisms of alanine aminotransferase (ALT) release from damaged and necrotic hepatocytes as an example of general biomarker mechanisms. by Andrew K Smith, Glen E P Ropella, Mitchell R McGill, Preethi Krishnan, Lopamudra Dutta, Ryan C Kennedy, Hartmut Jaeschke, C Anthony Hunt
Published in PLoS Computational Biology (2020-06-01)Get full text
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Liver-specific deletion of mechanistic target of rapamycin does not protect against acetaminophen-induced liver injury in mice by Hua Sun, Hong-Min Ni, Jennifer M. McCracken, Jephte Y Akakpo, Sam Fulte, Tara McKeen, Hartmut Jaeschke, Hua Wang, Wen-Xing Ding
Published in Liver Research (2021-06-01)Get full text
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Dual roles of p62/SQSTM1 in the injury and recovery phases of acetaminophen-induced liver injury in mice by Hui Qian, Qingyun Bai, Xiao Yang, Jephte Y. Akakpo, Lili Ji, Li Yang, Thomas Rülicke, Kurt Zatloukal, Hartmut Jaeschke, Hong-Min Ni, Wen-Xing Ding
Published in Acta Pharmaceutica Sinica B (2021-12-01)Get full text
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Fructose Protects Against Acetaminophen‐Induced Hepatotoxicity Mainly by Activating the Carbohydrate‐Response Element‐Binding Protein α–Fibroblast Growth Factor 21 Axis in Mice... by Deqiang Zhang, Sujuan Wang, Erin Ospina, Omar Shabandri, Daniel Lank, Jephte Y. Akakpo, Zifeng Zhao, Meichan Yang, Jun Wu, Hartmut Jaeschke, Pradip Saha, Xin Tong, Lei Yin
Published in Hepatology Communications (2021-06-01)Get full text
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High-throughput screening of novel TFEB agonists in protecting against acetaminophen-induced liver injury in mice by Xiaojuan Chao, Mengwei Niu, Shaogui Wang, Xiaowen Ma, Xiao Yang, Hua Sun, Xujia Hu, Hua Wang, Li Zhang, Ruili Huang, Menghang Xia, Andrea Ballabio, Hartmut Jaeschke, Hong-Min Ni, Wen-Xing Ding
Published in Acta Pharmaceutica Sinica B (2024-01-01)Get full text
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p53-Independent Induction of p21 Fails to Control Regeneration and Hepatocarcinogenesis in a Murine Liver Injury ModelSummary by Laura Elisa Buitrago-Molina, Silke Marhenke, Diana Becker, Robert Geffers, Timo Itzel, Andreas Teufel, Hartmut Jaeschke, André Lechel, Kristian Unger, Jovana Markovic, Amar Deep Sharma, Jens U. Marquardt, Michael Saborowski, Anna Saborowski, Arndt Vogel
Published in Cellular and Molecular Gastroenterology and Hepatology (2021-01-01)Get full text
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A non-human primate model of acute liver failure suitable for testing liver support systems by Ranjeet S. Kalsi, Alina Ostrowska, Alina Ostrowska, Alina Ostrowska, Adam Olson, Mubina Quader, Melvin Deutsch, Norma J. Arbujas-Silva, Jen Symmonds, Alejandro Soto-Gutierrez, Alejandro Soto-Gutierrez, Alejandro Soto-Gutierrez, John J. Crowley, Miguel Reyes-Mugica, Miguel Reyes-Mugica, Giselle Sanchez-Guerrero, Hartmut Jaeschke, Bruce P. Amiot, Marilia Cascalho, Scott L. Nyberg, Jeffrey L. Platt, Edgar N. Tafaleng, Ira J. Fox, Ira J. Fox, Ira J. Fox
Published in Frontiers in Medicine (2022-09-01)Get full text
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