Search Results - Jan Spanholtz
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384 Single-cell transcriptomics, proteomics and in vitro cytotoxicity of allogeneic cryopreserved natural killer cell therapy GTA002 identify potent effector signatures by Jan Spanholtz, Monica Raimo, Daniëlle Steenmans, Amanda van Vliet, Anna-Maria Georgoudaki, Adil Duru, Denise Vodegel
Published in Journal for ImmunoTherapy of Cancer (2023-11-01)Article -
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330 Combination therapy with stem cell derived natural killer cells and monoclonal antibodies leads to potent ADCC through engagement of endogenouse CD16 by Jan Spanholtz, Monica Raimo, Nina Lamers-Kok, Didem Özkazanc, Daniëlle Steenmans, Amanda van Vliet, Anna-Maria Georgoudaki, Adil Duru, Denise Vodegel
Published in Journal for ImmunoTherapy of Cancer (2023-11-01)Article -
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Closed-system manufacturing of therapeutic NK cells using automated cell enrichment and concentration processes enables scalable, robust and cost-effective solutions by Nina Kok, Zoë Dekkers, Anica Loos, Thomas Bos, Puck van den Broek, Inge Post, Bertine Niessen, Jan Spanholtz, Volker Huppert, Monica Raimo
Published in Frontiers in Bioengineering and Biotechnology (2025-06-01)Get full text
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Allogeneic NK cells induce monocyte-to-dendritic cell conversion, control tumor growth, and trigger a pro-inflammatory shift in patient-derived cultures of primary and metastatic c... by Tanja D de Gruijl, Jurriaan Tuynman, Jan Spanholtz, Hans J van der Vliet, Elisa C Toffoli, Amanda A van Vliet, Henk W M Verheul
Published in Journal for ImmunoTherapy of Cancer (2023-12-01)Get full text
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CD28 signaling domain boosts persistence and in vivo anti-tumor activity of stem cell-derived CD19-CAR-NK cells by Nina Kok, Didem Ozkazanc, Amanda A. van Vliet, Danielle Steenmans, Simar Pal Singh, Tolga Sutlu, Anna-Maria Georgoudaki, Monica Raimo, Jan Spanholtz, Adil Doganay Duru
Published in iScience (2025-06-01)Get full text
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Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34+ progenitor cell-derived NK cells by Amanda A. van Vliet, Ella Peters, Denise Vodegel, Daniëlle Steenmans, Monica Raimo, Susan Gibbs, Tanja D. de Gruijl, Adil D. Duru, Jan Spanholtz, Anna-Maria Georgoudaki
Published in iScience (2023-07-01)Get full text
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Combination of NK Cells and Cetuximab to Enhance Anti-Tumor Responses in RAS Mutant Metastatic Colorectal Cancer. by John Pradeep Veluchamy, Jan Spanholtz, Marleen Tordoir, Victor L Thijssen, Daniëlle A M Heideman, Henk M W Verheul, Tanja D de Gruijl, Hans J van der Vliet
Published in PLoS ONE (2016-01-01)Get full text
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Interlaboratory assessment of candidate reference materials for lentiviral vector copy number and integration site measurements by Hua-Jun He, Zhiyong He, Steven P. Lund, Laure Turner, Yongjun Fan, Yu Qiu, David C. Corney, Boro Dropulic, Rimas Orentas, Oxana Slessareva, Priscilla Welch, Katie Dungca, Ellen Stelloo, Gabrielle Dijksteel, Harma Feitsma, Sana Ahmed-Seghir, Rostyslav Makarenko, Engin Altunlu, Daniëlle Steenmans, Jan Spanholtz, Monica Raimo, Shai Senderovich, Barbara S. Paugh, Chieh-Yuan Li, Benjamin Schroeder, Alexandra S. Whale, Dilek Yener, Carole A. Foy, Shareef Nahas, Feng Tu, Michael Sheldon, Yan Ding, Jennifer Kandell, Uma Lakshmipathy, Jennifer H. McDaniel, Justin M. Zook, Sierra Miller, Samantha Maragh, Simona Patange, Mahir Mohiuddin, Alessandro Tona, Kenneth D. Cole, Sheng Lin-Gibson
Published in Molecular Therapy: Methods & Clinical Development (2025-06-01)Get full text
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