Search Results - Jason R Spence

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  1. 1

    A bioengineered niche promotes in vivo engraftment and maturation of pluripotent stem cell derived human lung organoids by Briana R Dye, Priya H Dedhia, Alyssa J Miller, Melinda S Nagy, Eric S White, Lonnie D Shea, Jason R Spence

    Published in eLife (2016-10-01)
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  2. 2

    Polymer Design of Microwell Hydrogels Influences Epithelial–Mesenchymal Interactions During Human Bronchosphere Formation by Madeline K. Eiken, Justin E. Levine, Shinyeong Lee, Samantha Lukpat, Eleanor M. Plaster, Vikram Bala, Jason R. Spence, Claudia Loebel

    Published in Advanced NanoBiomed Research (2025-01-01)
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  3. 3

    Efficient differentiation of human primordial germ cells through geometric control reveals a key role for Nodal signaling by Kyoung Jo, Seth Teague, Bohan Chen, Hina Aftab Khan, Emily Freeburne, Hunter Li, Bolin Li, Ran Ran, Jason R Spence, Idse Heemskerk

    Published in eLife (2022-04-01)
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  4. 4

    Neural Crest Cell Implantation Restores Enteric Nervous System Function and Alters the Gastrointestinal Transcriptome in Human Tissue-Engineered Small Intestine by Christopher R. Schlieve, Kathryn L. Fowler, Matthew Thornton, Sha Huang, Ibrahim Hajjali, Xiaogang Hou, Brendan Grubbs, Jason R. Spence, Tracy C. Grikscheit

    Published in Stem Cell Reports (2017-09-01)
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  5. 5

    Near-Infrared In Vivo Imaging of Claudin-1 Expression by Orthotopically Implanted Patient-Derived Colonic Adenoma Organoids by Sangeeta Jaiswal, Fa Wang, Xiaoli Wu, Tse-Shao Chang, Ahmad Shirazi, Miki Lee, Michael K. Dame, Jason R. Spence, Thomas D. Wang

    Published in Diagnostics (2024-01-01)
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  6. 6

    Perfusion System for Modification of Luminal Contents of Human Intestinal Organoids and Realtime Imaging Analysis of Microbial Populations by Nicholas J. Ginga, Raleigh Slyman, Ge-Ah Kim, Eric Parigoris, Sha Huang, Veda K. Yadagiri, Vincent B. Young, Jason R. Spence, Shuichi Takayama

    Published in Micromachines (2022-01-01)
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  7. 7

    Integrating mechanical cues with engineered platforms to explore cardiopulmonary development and disease by Donia W. Ahmed, Madeline K. Eiken, Samuel J. DePalma, Adam S. Helms, Rachel L. Zemans, Jason R. Spence, Brendon M. Baker, Claudia Loebel

    Published in iScience (2023-12-01)
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  8. 8

    A Dynamic WNT/β-CATENIN Signaling Environment Leads to WNT-Independent and WNT-Dependent Proliferation of Embryonic Intestinal Progenitor Cells by Alana M. Chin, Yu-Hwai Tsai, Stacy R. Finkbeiner, Melinda S. Nagy, Emily M. Walker, Nicole J. Ethen, Bart O. Williams, Michele A. Battle, Jason R. Spence

    Published in Stem Cell Reports (2016-11-01)
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  9. 9

    Integrative genome-scale analyses reveal post-transcriptional signatures of early human small intestinal development in a directed differentiation organoid model by Yu-Han Hung, Meghan Capeling, Jonathan W. Villanueva, Matt Kanke, Michael T. Shanahan, Sha Huang, Rebecca Cubitt, Vera D. Rinaldi, John C. Schimenti, Jason R. Spence, Praveen Sethupathy

    Published in BMC Genomics (2023-10-01)
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  10. 10

    In Vitro Induction and In Vivo Engraftment of Lung Bud Tip Progenitor Cells Derived from Human Pluripotent Stem Cells by Alyssa J. Miller, David R. Hill, Melinda S. Nagy, Yoshiro Aoki, Briana R. Dye, Alana M. Chin, Sha Huang, Felix Zhu, Eric S. White, Vibha Lama, Jason R. Spence

    Published in Stem Cell Reports (2018-01-01)
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  11. 11

    SOX9 suppresses colon cancer via inhibiting epithelial-mesenchymal transition and SOX2 induction by Ying Feng, Ningxin Zhu, Karan Bedi, Jinju Li, Chamila Perera, Maranne Green, Naziheh Assarzadegan, Yali Zhai, Qingzhi Liu, Veerabhadran Baladandayuthapani, Jason R. Spence, Kathleen R. Cho, Eric R. Fearon

    Published in The Journal of Clinical Investigation (2025-06-01)
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  12. 12

    Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung by Tristan Frum, Peggy P. Hsu, Renee F. C. Hein, Ansley S. Conchola, Charles J. Zhang, Olivia R. Utter, Abhinav Anand, Yi Zhang, Sydney G. Clark, Ian Glass, Jonathan Z. Sexton, Jason R. Spence

    Published in npj Regenerative Medicine (2023-09-01)
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  13. 13

    Generation of tissue-engineered small intestine using embryonic stem cell-derived human intestinal organoids by Stacy R. Finkbeiner, Jennifer J. Freeman, Minna M. Wieck, Wael El-Nachef, Christopher H. Altheim, Yu-Hwai Tsai, Sha Huang, Rachel Dyal, Eric S. White, Tracy C. Grikscheit, Daniel H. Teitelbaum, Jason R. Spence

    Published in Biology Open (2015-11-01)
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  14. 14

    In vitro generation of human pluripotent stem cell derived lung organoids by Briana R Dye, David R Hill, Michael AH Ferguson, Yu-Hwai Tsai, Melinda S Nagy, Rachel Dyal, James M Wells, Christopher N Mayhew, Roy Nattiv, Ophir D Klein, Eric S White, Gail H Deutsch, Jason R Spence

    Published in eLife (2015-03-01)
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  15. 15

    Neutrophil prime unique transcriptional responses in intestinal organoids during infection with nontyphoidal Salmonella enterica serovars by Anna-Lisa E. Lawrence, Ryan P. Berger, David R. Hill, Sha Huang, Veda K. Yadagiri, Brooke Bons, Courtney Fields, Jason S. Knight, Christiane E. Wobus, Jason R. Spence, Vincent B. Young, Basel H. Abuaita, Mary X. O'Riordan

    Published in mSphere (2024-12-01)
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  16. 16

    Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids by Meghan M. Capeling, Michael Czerwinski, Sha Huang, Yu-Hwai Tsai, Angeline Wu, Melinda S. Nagy, Benjamin Juliar, Nambirajan Sundaram, Yang Song, Woojin M. Han, Shuichi Takayama, Eben Alsberg, Andres J. Garcia, Michael Helmrath, Andrew J. Putnam, Jason R. Spence

    Published in Stem Cell Reports (2019-02-01)
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  17. 17

    Bacterial colonization stimulates a complex physiological response in the immature human intestinal epithelium by David R Hill, Sha Huang, Melinda S Nagy, Veda K Yadagiri, Courtney Fields, Dishari Mukherjee, Brooke Bons, Priya H Dedhia, Alana M Chin, Yu-Hwai Tsai, Shrikar Thodla, Thomas M Schmidt, Seth Walk, Vincent B Young, Jason R Spence

    Published in eLife (2017-11-01)
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  18. 18

    Induced organoids derived from patients with ulcerative colitis recapitulate colitic reactivity by Samaneh K. Sarvestani, Steven Signs, Bo Hu, Yunku Yeu, Hao Feng, Ying Ni, David R. Hill, Robert C. Fisher, Sylvain Ferrandon, Reece K. DeHaan, Jennifer Stiene, Michael Cruise, Tae Hyun Hwang, Xiling Shen, Jason R. Spence, Emina H. Huang

    Published in Nature Communications (2021-01-01)
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  19. 19

    TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice by Yu-chi Shen, Adrienne Niederriter Shami, Lindsay Moritz, Hailey Larose, Gabriel L. Manske, Qianyi Ma, Xianing Zheng, Meena Sukhwani, Michael Czerwinski, Caleb Sultan, Haolin Chen, Stephen J. Gurczynski, Jason R. Spence, Kyle E. Orwig, Michelle Tallquist, Jun Z. Li, Saher Sue Hammoud

    Published in Nature Communications (2021-06-01)
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  20. 20

    Lumen Formation Is an Intrinsic Property of Isolated Human Pluripotent Stem Cells by Kenichiro Taniguchi, Yue Shao, Ryan F. Townshend, Yu-Hwai Tsai, Cynthia J. DeLong, Shawn A. Lopez, Srimonta Gayen, Andrew M. Freddo, Deming J. Chue, Dennis J. Thomas, Jason R. Spence, Benjamin Margolis, Sundeep Kalantry, Jianping Fu, K. Sue O’Shea, Deborah L. Gumucio

    Published in Stem Cell Reports (2015-12-01)
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