Search Results - Javier Chaparro-Riggers

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  1. 1

    Pharmacokinetics, pharmacodynamics, and toxicity of a PD-1-targeted IL-15 in cynomolgus monkeys. by Changhua Ji, Bing Kuang, Bernard S Buetow, Allison Vitsky, Yuanming Xu, Tzu-Hsuan Huang, Javier Chaparro-Riggers, Eugenia Kraynov, Diane Matsumoto

    Published in PLoS ONE (2024-01-01)
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  2. 2

    Nanomechanical binding mechanism of ligands drives agonistic activity by Hannah Seferovic, Patricia Sticht, Lisa Hain, Rong Zhu, Sebastian Diethör, Christian Wechselberger, Florian Weber, David Bernhard, Birgit Plochberger, Yoo Jin Oh, Javier Chaparro-Riggers, Peter Hinterdorfer

    Published in Nature Communications (2025-07-01)
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  3. 3

    CD40 agonist-induced IL-12p40 potentiates hepatotoxicity by Wei Chen, Yan Qu, Shahram Salek-Ardakani, Graham Thomas, Jonathan Heyen, Javier Chaparro-Riggers, Caroline Bonnans, Wenqian He, Bernard Buetow, Min Liao, Breanna Jung, Smitha Pillai, Diane Matsumoto

    Published in Journal for ImmunoTherapy of Cancer (2020-05-01)
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  4. 4

    Structural elucidation of the haptoglobin-hemoglobin clearance mechanism by macrophage scavenger receptor CD163. by Ching-Shin Huang, Hui Wang, Joshua B R White, Oksana Degtjarik, Cindy Huynh, Kristoffer Brannstrom, Mark T Horn, Stephen P Muench, William S Somers, Javier Chaparro-Riggers, Laura Lin, Lidia Mosyak

    Published in PLoS Biology (2025-07-01)
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  5. 5

    267 Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes anti-tumor immunity and improves therapeutic window by Shahram Salek-Ardakani, Wenjing Yang, Sheng Ding, Shih-Hsun Chen, Jessica Stanfield, Nadia Kurd, Ryan Llewellyn, Jonathan Heyen, Carole Wang, Zea Melton, Javier Chaparro-Riggers, Pawel Dominik, Kevin Lindquist, Thomas Van Blarcom

    Published in Journal for ImmunoTherapy of Cancer (2021-11-01)
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  6. 6

    Dual checkpoint blockade of CD47 and PD-L1 using an affinity-tuned bispecific antibody maximizes antitumor immunity by Shahram Salek-Ardakani, Wenjing Yang, Sheng Ding, Shih-Hsun Chen, Pawel K Dominik, Jessica Stanfield, Nadia Kurd, Ryan Llewellyn, Jonathan Heyen, Carole Wang, Zea Melton, Thomas Van Blarcom, Kevin C Lindquist, Javier Chaparro-Riggers

    Published in Journal for ImmunoTherapy of Cancer (2021-10-01)
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  7. 7

    One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics by Wei Chen, Fan Yang, Carole Wang, Jatin Narula, Edward Pascua, Irene Ni, Sheng Ding, Xiaodi Deng, Matthew Ling-Hon Chu, Amber Pham, Xiaoyue Jiang, Kevin C. Lindquist, Patrick J. Doonan, Tom Van Blarcom, Yik Andy Yeung, Javier Chaparro-Riggers

    Published in mAbs (2021-01-01)
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