Search Results - Jessica Tyrrell
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Latent class growth mixture modeling of HbA1C trajectories identifies individuals at high risk of developing complications of type 2 diabetes mellitus in the UK Biobank by Jessica Tyrrell, Renu Bala, Cathryn M Lewis, Dale Handley, Alexandra C Gillett
Published in BMJ Open Diabetes Research & Care (2025-09-01)Get full text
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Mendelian Randomization Analyses Suggest Childhood Body Size Indirectly Influences End Points From Across the Cardiovascular Disease Spectrum Through Adult Body Size by Grace M. Power, Jessica Tyrrell, Timothy M. Frayling, George Davey Smith, Tom G. Richardson
Published in Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease (2021-09-01)Get full text
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Body mass index and inflammation in depression and treatment-resistant depression: a Mendelian randomisation study by Vasilios Karageorgiou, Francesco Casanova, Jessica O’Loughlin, Harry Green, Trevelyan J. McKinley, Jack Bowden, Jessica Tyrrell
Published in BMC Medicine (2023-09-01)Get full text
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Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study by Francesco Casanova, Jessica O’Loughlin, Vasilis Karageorgiou, Robin N. Beaumont, Jack Bowden, Andrew R. Wood, Jessica Tyrrell
Published in BMC Medicine (2023-12-01)Get full text
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A genome-wide association study identifies 5 loci associated with frozen shoulder and implicates diabetes as a causal risk factor. by Harry D Green, Alistair Jones, Jonathan P Evans, Andrew R Wood, Robin N Beaumont, Jessica Tyrrell, Timothy M Frayling, Christopher Smith, Michael N Weedon
Published in PLoS Genetics (2021-06-01)Get full text
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Identification and analysis of individuals who deviate from their genetically-predicted phenotype. by Gareth Hawkes, Loic Yengo, Sailaja Vedantam, Eirini Marouli, Robin N Beaumont, GIANT Consortium, Jessica Tyrrell, Michael N Weedon, Joel Hirschhorn, Timothy M Frayling, Andrew R Wood
Published in PLoS Genetics (2023-09-01)Get full text
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Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis. by William D Thompson, Jessica Tyrrell, Maria-Carolina Borges, Robin N Beaumont, Bridget A Knight, Andrew R Wood, Susan M Ring, Andrew T Hattersley, Rachel M Freathy, Debbie A Lawlor
Published in PLoS Medicine (2019-06-01)Get full text
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IgA Nephropathy Genetic Risk Score to Estimate the Prevalence of IgA Nephropathy in UK Biobank by Kittiya Sukcharoen, Seth A. Sharp, Nicholas J. Thomas, Robert A. Kimmitt, Jamie Harrison, Coralie Bingham, Monika Mozere, Michael N. Weedon, Jessica Tyrrell, Jonathan Barratt, Daniel P. Gale, Richard A. Oram
Published in Kidney International Reports (2020-10-01)Get full text
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Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records by Katherine S. Ruth, Robin N. Beaumont, Jonathan M. Locke, Jessica Tyrrell, Carolyn J. Crandall, Gareth Hawkes, Timothy M. Frayling, Julia K. Prague, Kashyap A. Patel, Andrew R. Wood, Michael N. Weedon, Anna Murray
Published in BMC Medical Genomics (2023-10-01)Get full text
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BMI and well-being in people of East Asian and European ancestry: a Mendelian randomisation study by Jessica O’Loughlin, Francesco Casanova, Amanda Hughes, Zammy Fairhurst-Hunter, Liming Li, Zhengming Chen, China Kadoorie Biobank Collaborative Group, Jack Bowden, Ed Watkins, Rachel M. Freathy, Laura D. Howe, Robin G. Walters, Jessica Tyrrell
Published in Translational Psychiatry (2023-07-01)Get full text
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Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis by Pavel Loginovic, Feiyi Wang, Jiang Li, Lauric Ferrat, Uyenlinh L. Mirshahi, H. Shanker Rao, Axel Petzold, Jessica Tyrrell, Harry D. Green, Michael N. Weedon, Andrea Ganna, Tiinamaija Tuomi, David J. Carey, UKBB Eye & Vision Consortium, FinnGen, Geisinger-Regeneron DiscovEHR Collaboration, Richard A. Oram, Tasanee Braithwaite
Published in Nature Communications (2024-02-01)Get full text
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Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers. by Luke C Pilling, Janice L Atkins, Michael O Duff, Robin N Beaumont, Samuel E Jones, Jessica Tyrrell, Chia-Ling Kuo, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Andrew R Wood, Anna Murray, Michael N Weedon, Lorna W Harries, George A Kuchel, Luigi Ferrucci, Timothy M Frayling, David Melzer
Published in PLoS ONE (2017-01-01)Get full text
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Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study. by Mark Gormley, James Yarmolinsky, Tom Dudding, Kimberley Burrows, Richard M Martin, Steven Thomas, Jessica Tyrrell, Paul Brennan, Miranda Pring, Stefania Boccia, Andrew F Olshan, Brenda Diergaarde, Rayjean J Hung, Geoffrey Liu, Danny Legge, Eloiza H Tajara, Patricia Severino, Martin Lacko, Andrew R Ness, George Davey Smith, Emma E Vincent, Rebecca C Richmond
Published in PLoS Genetics (2021-04-01)Get full text
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A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure by Timothy M. Frayling, Robin N. Beaumont, Samuel E. Jones, Hanieh Yaghootkar, Marcus A. Tuke, Katherine S. Ruth, Francesco Casanova, Ben West, Jonathan Locke, Seth Sharp, Yingjie Ji, William Thompson, Jamie Harrison, Amy S. Etheridge, Paul J. Gallins, Dereje Jima, Fred Wright, Yihui Zhou, Federico Innocenti, Cecilia M. Lindgren, Niels Grarup, Anna Murray, Rachel M. Freathy, Michael N. Weedon, Jessica Tyrrell, Andrew R. Wood
Published in Cell Reports (2018-04-01)Get full text
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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation by Susan Martin, Jessica Tyrrell, E Louise Thomas, Matthew J Bown, Andrew R Wood, Robin N Beaumont, Lam C Tsoi, Philip E Stuart, James T Elder, Philip Law, Richard Houlston, Christopher Kabrhel, Nikos Papadimitriou, Marc J Gunter, Caroline J Bull, Joshua A Bell, Emma E Vincent, Naveed Sattar, Malcolm G Dunlop, Ian PM Tomlinson, Sara Lindström, INVENT consortium, Jimmy D Bell, Timothy M Frayling, Hanieh Yaghootkar
Published in eLife (2022-01-01)Get full text
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Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci. by Samuel E Jones, Jessica Tyrrell, Andrew R Wood, Robin N Beaumont, Katherine S Ruth, Marcus A Tuke, Hanieh Yaghootkar, Youna Hu, Maris Teder-Laving, Caroline Hayward, Till Roenneberg, James F Wilson, Fabiola Del Greco, Andrew A Hicks, Chol Shin, Chang-Ho Yun, Seung Ku Lee, Andres Metspalu, Enda M Byrne, Philip R Gehrman, Henning Tiemeier, Karla V Allebrandt, Rachel M Freathy, Anna Murray, David A Hinds, Timothy M Frayling, Michael N Weedon
Published in PLoS Genetics (2016-08-01)Get full text
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Integrating multiple lines of evidence to assess the effects of maternal BMI on pregnancy and perinatal outcomes by Maria Carolina Borges, Gemma L. Clayton, Rachel M. Freathy, Janine F. Felix, Alba Fernández-Sanlés, Ana Gonçalves Soares, Fanny Kilpi, Qian Yang, Rosemary R. C. McEachan, Rebecca C. Richmond, Xueping Liu, Line Skotte, Amaia Irizar, Andrew T. Hattersley, Barbara Bodinier, Denise M. Scholtens, Ellen A. Nohr, Tom A. Bond, M. Geoffrey Hayes, Jane West, Jessica Tyrrell, John Wright, Luigi Bouchard, Mario Murcia, Mariona Bustamante, Marc Chadeau-Hyam, Marjo-Riitta Jarvelin, Martine Vrijheid, Patrice Perron, Per Magnus, Romy Gaillard, Vincent W. V. Jaddoe, William L. Lowe, Bjarke Feenstra, Marie-France Hivert, Thorkild I. A. Sørensen, Siri E. Håberg, Sylvain Serbert, Maria Magnus, Deborah A. Lawlor
Published in BMC Medicine (2024-01-01)Get full text
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