Search Results - Joshua Chiou

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  1. 1

    Glucocorticoid signaling in pancreatic islets modulates gene regulatory programs and genetic risk of type 2 diabetes. by Anthony Aylward, Mei-Lin Okino, Paola Benaglio, Joshua Chiou, Elisha Beebe, Jose Andres Padilla, Sharlene Diep, Kyle J Gaulton

    Published in PLoS Genetics (2021-05-01)
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  2. 2

    The influence of HLA genetic variation on plasma protein expression by Chirag Krishna, Joshua Chiou, Saori Sakaue, Joyce B. Kang, Stephen M. Christensen, Isac Lee, Melis Atalar Aksit, Hye In Kim, David von Schack, Soumya Raychaudhuri, Daniel Ziemek, Xinli Hu

    Published in Nature Communications (2024-07-01)
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  3. 3

    Mapping genetic effects on cell type-specific chromatin accessibility and annotating complex immune trait variants using single nucleus ATAC-seq in peripheral blood. by Paola Benaglio, Jacklyn Newsome, Jee Yun Han, Joshua Chiou, Anthony Aylward, Sierra Corban, Michael Miller, Mei-Lin Okino, Jaspreet Kaur, Sebastian Preissl, David U Gorkin, Kyle J Gaulton

    Published in PLoS Genetics (2023-06-01)
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  4. 4

    Multi-INTACT: integrative analysis of the genome, transcriptome, and proteome identifies causal mechanisms of complex traits by Jeffrey Okamoto, Xianyong Yin, Brady Ryan, Joshua Chiou, Francesca Luca, Roger Pique-Regi, Hae Kyung Im, Jean Morrison, Charles Burant, Eric B. Fauman, Markku Laakso, Michael Boehnke, Xiaoquan Wen

    Published in Genome Biology (2025-02-01)
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  5. 5

    Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development by Ryan J Geusz, Allen Wang, Joshua Chiou, Joseph J Lancman, Nichole Wetton, Samy Kefalopoulou, Jinzhao Wang, Yunjiang Qiu, Jian Yan, Anthony Aylward, Bing Ren, P Duc Si Dong, Kyle J Gaulton, Maike Sander

    Published in eLife (2021-02-01)
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  6. 6

    Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. by Miriam S Udler, Jaegil Kim, Marcin von Grotthuss, Sílvia Bonàs-Guarch, Joanne B Cole, Joshua Chiou, Christopher D. Anderson on behalf of METASTROKE and the ISGC, Michael Boehnke, Markku Laakso, Gil Atzmon, Benjamin Glaser, Josep M Mercader, Kyle Gaulton, Jason Flannick, Gad Getz, Jose C Florez

    Published in PLoS Medicine (2018-09-01)
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  7. 7

    Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus by Krista Freimann, Anneke Brümmer, Robert Warmerdam, Tarran S. Rupall, Ana Laura Hernández-Ledesma, Joshua Chiou, Emily R. Holzinger, Joseph C. Maranville, Nikolina Nakic, Halit Ongen, Luca Stefanucci, Michael C. Turchin, eQTLGen Consortium, Lude Franke, Urmo Võsa, Carla P. Jones, Alejandra Medina-Rivera, Gosia Trynka, Kai Kisand, Sven Bergmann, Kaur Alasoo

    Published in Nature Communications (2025-10-01)
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  8. 8

    Nutrient regulation of the islet epigenome controls adaptive insulin secretion by Matthew Wortham, Fenfen Liu, Austin R. Harrington, Johanna Y. Fleischman, Martina Wallace, Francesca Mulas, Medhavi Mallick, Nicholas K. Vinckier, Benjamin R. Cross, Joshua Chiou, Nisha A. Patel, Yinghui Sui, Carolyn McGrail, Yesl Jun, Gaowei Wang, Ulupi S. Jhala, Roland Schüle, Orian S. Shirihai, Mark O. Huising, Kyle J. Gaulton, Christian M. Metallo, Maike Sander

    Published in The Journal of Clinical Investigation (2023-04-01)
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  9. 9

    Single-cell multiomic profiling of human lungs reveals cell-type-specific and age-dynamic control of SARS-CoV2 host genes by Allen Wang, Joshua Chiou, Olivier B Poirion, Justin Buchanan, Michael J Valdez, Jamie M Verheyden, Xiaomeng Hou, Parul Kudtarkar, Sharvari Narendra, Jacklyn M Newsome, Minzhe Guo, Dina A Faddah, Kai Zhang, Randee E Young, Justinn Barr, Eniko Sajti, Ravi Misra, Heidie Huyck, Lisa Rogers, Cory Poole, Jeffery A Whitsett, Gloria Pryhuber, Yan Xu, Kyle J Gaulton, Sebastian Preissl, Xin Sun, NHLBI LungMap Consortium

    Published in eLife (2020-11-01)
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