Search Results - Lyle L Moldawer

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  1. 1

    Defining critical illness using immunological endotypes in patients with and without sepsis: a cohort study by Jeremy A. Balch, Uan-I Chen, Oliver Liesenfeld, Petr Starostik, Tyler J. Loftus, Philip A. Efron, Scott C. Brakenridge, Timothy E. Sweeney, Lyle L. Moldawer

    Published in Critical Care (2023-07-01)
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  2. 2

    Unique transcriptomic response to sepsis is observed among patients of different age groups. by Steven L Raymond, María Cecilia López, Henry V Baker, Shawn D Larson, Philip A Efron, Timothy E Sweeney, Purvesh Khatri, Lyle L Moldawer, James L Wynn

    Published in PLoS ONE (2017-01-01)
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  3. 3

    Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner by Quan Vo, Zachary D. Simon, Gwoncheol Park, Dina C Nacionales, Carmelina Gorski, Evan L Barrios, Gemma Casadesus, Philip A Efron, Lyle L Moldawer, Ravinder Nagpal, Paramita Chakrabarty, Marcelo Febo

    Published in NeuroImage (2025-01-01)
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  4. 4

    Corrigendum to “Functional connectivity within sensorimotor cortical and striatal regions is regulated by sepsis in a sex-dependent manner” [NeuroImage 305 (2025) 120995] by Quan Vo, Zachary D. Simon, Gwoncheol Park, Dina C Nacionales, Carmelina Gorski, Evan L Barrios, Gemma Casadesus, Philip A Efron, Lyle L Moldawer, Ravinder Nagpal, Paramita Chakrabarty, Marcelo Febo

    Published in NeuroImage (2025-03-01)
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  5. 5

    Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study by Julie A. Stortz, Michael C. Cox, Russell B. Hawkins, Gabriela L. Ghita, Babette A. Brumback, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron, Scott C. Brakenridge, Frederick A. Moore

    Published in Critical Care (2020-05-01)
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  6. 6

    LIPid Intensive Drug therapy for Sepsis Pilot (LIPIDS-P): Phase I/II clinical trial protocol of lipid emulsion therapy for stabilising cholesterol levels in sepsis and septic shock by Marie Crandall, Lisa Jones, Faheem W Guirgis, Lauren Page Black, Martin Daniel Rosenthal, Morgan Henson, Jason Ferreira, Christiaan Leeuwenburgh, Colleen Kalynych, Lyle L Moldawer, Taylor Miller, Srinivasa T Reddy, Samuel S Wu, Frederick A Moore

    Published in BMJ Open (2019-09-01)
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  7. 7

    Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial by Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-François Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L. Moldawer, Richard Hotchkiss, Bruno François

    Published in Annals of Intensive Care (2023-03-01)
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  8. 8

    Host responses to sepsis vary in different low-lethality murine models. by Lori F Gentile, Dina C Nacionales, M Cecilia Lopez, Erin Vanzant, Angela Cuenca, Benjamin E Szpila, Alex G Cuenca, Anna Joseph, Frederick A Moore, Christiaan Leeuwenburgh, Henry V Baker, Lyle L Moldawer, Philip A Efron

    Published in PLoS ONE (2014-01-01)
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  9. 9

    Innate immune training in the neonatal response to sepsis by Jaimar C. Rincon, Dayuan Wang, Valerie E. Polcz, Evan L. Barrios, Marvin L. Dirain, Ricardo F. Ungaro, Dina C. Nacionales, Leilani Zeumer-Spataro, Feifei Xiao, Philip A. Efron, Lyle L. Moldawer, Guoshuai Cai, Shawn D. Larson

    Published in Molecular Medicine (2025-04-01)
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  10. 10

    MerTK-dependent efferocytosis by monocytic-MDSCs mediates resolution of ischemia/reperfusion injury after lung transplant by Victoria Leroy, Denny J. Manual Kollareth, Zhenxiao Tu, Jeff Arni C. Valisno, Makena Woolet-Stockton, Biplab Saha, Amir M. Emtiazjoo, Mindaugas Rackauskas, Lyle L. Moldawer, Philip A. Efron, Guoshuai Cai, Carl Atkinson, Gilbert R. Upchurch Jr., Ashish K. Sharma

    Published in JCI Insight (2024-10-01)
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  11. 11

    Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications by Lael M. Yonker, Oluwakemi Badaki-Makun, Puneeta Arya, Brittany P. Boribong, Gabriela Moraru, Brittany Fenner, Jaimar Rincon, Alex Hopke, Brent Rogers, Jeremiah Hinson, Alessio Fasano, Lilly Lee, Sarah M. Kehoe, Shawn D. Larson, Hector Chavez, Scott Levin, Lyle L. Moldawer, Daniel Irimia

    Published in BMC Infectious Diseases (2022-06-01)
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  12. 12

    Determining potential immunomodulatory drug efficacy in sepsis using ELISpot by Andrew H. Walton, Monty B. Mazer, Kenneth E. Remy, Dale F. Osborne, Ethan B. Davitt, Thomas S. Griffith, Robert W. Gould, Vladimir P. Badovinac, Scott C. Brakenridge, Anne M. Drewry, Ricardo F. Ungaro, Ivanna L. Rocha, Tyler J. Loftus, Philip A. Efron, Lyle L. Moldawer, Charles C. Caldwell, Richard S. Hotchkiss

    Published in Scientific Reports (2025-04-01)
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  13. 13

    Monocyte anisocytosis corresponds with increasing severity of COVID-19 in children by Abigail S. Kane, Abigail S. Kane, Brittany P. Boribong, Brittany P. Boribong, Brittany P. Boribong, Maggie Loiselle, Maggie Loiselle, Anagha P. Chitnis, Hector Chavez, Hector Chavez, Lyle L. Moldawer, Shawn D. Larson, Oluwakemi Badaki-Makun, Oluwakemi Badaki-Makun, Daniel Irimia, Daniel Irimia, Daniel Irimia, Lael M. Yonker, Lael M. Yonker, Lael M. Yonker

    Published in Frontiers in Pediatrics (2023-06-01)
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  14. 14

    A randomized, double-blind, placebo-controlled trial of IL-7 in critically ill patients with COVID-19 by Manu Shankar-Hari, Bruno Francois, Kenneth E. Remy, Cristina Gutierrez, Stephen Pastores, Thomas Daix, Robin Jeannet, Jane Blood, Andrew H. Walton, Reinaldo Salomao, Georg Auzinger, David Striker, Robert S. Martin, Nitin J. Anand, James Bosanquet, Teresa Blood, Scott Brakenridge, Lyle L. Moldawer, Vidula Vachharajani, Cassian Yee, Felipe Dal-Pizzol, Michel Morre, Frederique Berbille, Marcel van den Brink, Richard Hotchkiss

    Published in JCI Insight (2025-03-01)
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  15. 15

    Monocyte Anisocytosis Can Discriminate Between Sepsis and Sterile Inflammation, but not Mortality, in Critically Ill Surgical/Trauma Patients: A Secondary Prospective Analysis by Miguel Hernández-Ríos, MD, Ruoxuan Wu, MS, Valerie A. Polcz, MD, Rachel D. Burnside, PhD, Lael M. Yonker, MD, Daniel Irimia, MD, PhD, Feifei Xiao, PhD, Jaimar C. Rincon, PhD, Tyler J. Loftus, MD, PhD, Lyle L. Moldawer, PhD, Robert Maile, PhD, Philip A. Efron, MD, Muxuan Liang, PhD

    Published in Critical Care Explorations (2025-09-01)
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  16. 16

    The post-septic peripheral myeloid compartment reveals unexpected diversity in myeloid-derived suppressor cells by Evan L. Barrios, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Micah Willis, Valerie E. Polcz, Gwendolyn S. Gillies, Jennifer A. Munley, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie-Pierre L. Gauthier, Shawn D. Larson, Laurence Morel, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Michael P. Kladde, Clayton E. Mathews, Maigan A. Brusko, Todd M. Brusko, Lyle L. Moldawer, Rhonda Bacher, Philip A. Efron

    Published in Frontiers in Immunology (2024-04-01)
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  17. 17

    A community approach to mortality prediction in sepsis via gene expression analysis by Timothy E. Sweeney, Thanneer M. Perumal, Ricardo Henao, Marshall Nichols, Judith A. Howrylak, Augustine M. Choi, Jesús F. Bermejo-Martin, Raquel Almansa, Eduardo Tamayo, Emma E. Davenport, Katie L. Burnham, Charles J. Hinds, Julian C. Knight, Christopher W. Woods, Stephen F. Kingsmore, Geoffrey S. Ginsburg, Hector R. Wong, Grant P. Parnell, Benjamin Tang, Lyle L. Moldawer, Frederick E. Moore, Larsson Omberg, Purvesh Khatri, Ephraim L. Tsalik, Lara M. Mangravite, Raymond J. Langley

    Published in Nature Communications (2018-02-01)
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  18. 18

    Surviving septic patients endotyped with a functional assay demonstrate active immune responses by Adam D. Price, Ellen R. Becker, Evan L. Barrios, Monty B. Mazer, Patrick W. McGonagill, Christian B. Bergmann, Michael D. Goodman, Robert W. Gould, Mahil Rao, Valerie E. Polcz, Tamara A. Kucaba, Andrew H. Walton, Sydney Miles, Julie Xu, Muxuan Liang, Tyler J. Loftus, Philip A. Efron, Kenneth E. Remy, Scott C. Brakenridge, Vladimir P. Badovinac, Vladimir P. Badovinac, Vladimir P. Badovinac, Thomas S. Griffith, Thomas S. Griffith, Thomas S. Griffith, Lyle L. Moldawer, Richard S. Hotchkiss, Charles C. Caldwell

    Published in Frontiers in Immunology (2024-10-01)
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  19. 19

    Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness by Evan L. Barrios, Leandro Balzano-Nogueira, Valerie E. Polcz, Christine Rodhouse, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Shawn D. Larson, Ashish Sharma, Gilburt Upchurch, Shannon M. Wallet, Todd M. Brusko, Todd M. Brusko, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Rhonda Bacher, Rhonda Bacher, Guoshuai Cai, Michael P. Kladde, Clayton E. Mathews, Lyle L. Moldawer, Maigan A. Brusko, Maigan A. Brusko, Philip A. Efron

    Published in Frontiers in Immunology (2024-12-01)
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  20. 20

    Adverse outcomes and an immunosuppressed endotype in septic patients with reduced IFN-γ ELISpot by Evan L. Barrios, Monty B. Mazer, Patrick W. McGonagill, Christian B. Bergmann, Michael D. Goodman, Robert W. Gould, Mahil Rao, Valerie E. Polcz, Ruth J. Davis, Drew E. Del Toro, Marvin L.S. Dirain, Alexandra Dram, Lucas O. Hale, Mohammad Heidarian, Caleb Y. Kim, Tamara A. Kucaba, Jennifer P. Lanz, Ashley E. McCray, Sandra Meszaros, Sydney Miles, Candace R. Nelson, Ivanna L. Rocha, Elvia E. Silva, Ricardo F. Ungaro, Andrew H. Walton, Julie Xu, Leilani Zeumer-Spataro, Anne M. Drewry, Muxuan Liang, Letitia E. Bible, Tyler J. Loftus, Isaiah R. Turnbull, Philip A. Efron, Kenneth E. Remy, Scott C. Brakenridge, Vladimir P. Badovinac, Thomas S. Griffith, Lyle L. Moldawer, Richard S. Hotchkiss, Charles C. Caldwell

    Published in JCI Insight (2024-01-01)
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