Search Results - Mark R Cookson

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  1. 1

    Leucine-Rich Repeat Kinase 2 Mutations and Parkinson's Disease: Three Questions by Elisa Greggio, Mark R Cookson

    Published in ASN Neuro (2009-03-01)
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  2. 2

    Generation of gene-corrected isogenic controls from Parkinson's disease patient iPSC lines carrying the pathogenic SNCA p.A53T variant by Nikita Kozhushko, Aleksandra Beilina, Mark R. Cookson

    Published in Stem Cell Research (2023-06-01)
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  3. 3

    Post-translational decrease in respiratory chain proteins in the Polg mutator mouse brain. by David N Hauser, Allissa A Dillman, Jinhui Ding, Yan Li, Mark R Cookson

    Published in PLoS ONE (2014-01-01)
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  4. 4

    Structure and regulation of full-length human leucine-rich repeat kinase 1 by Riley D. Metcalfe, Juliana A. Martinez Fiesco, Luis Bonet-Ponce, Jillian H. Kluss, Mark R. Cookson, Ping Zhang

    Published in Nature Communications (2023-08-01)
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  5. 5

    Variant biomarker discovery using mass spectrometry-based proteogenomics by Luke Reilly, Sahba Seddighi, Andrew B. Singleton, Andrew B. Singleton, Mark R. Cookson, Michael E. Ward, Yue A. Qi

    Published in Frontiers in Aging (2023-04-01)
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  6. 6

    14-3-3 binding maintains the Parkinson’s associated kinase LRRK2 in an inactive state by Juliana A. Martinez Fiesco, Alexandra Beilina, Astrid Alvarez de la Cruz, Ning Li, Riley D. Metcalfe, Mark R. Cookson, Ping Zhang

    Published in Nature Communications (2025-08-01)
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  7. 7

    Identification of Stk25 as a genetic modifier of Tau phosphorylation in Dab1-mutant mice. by Tohru Matsuki, Mariam Zaka, Rita Guerreiro, Marcel P van der Brug, Jonathan A Cooper, Mark R Cookson, John A Hardy, Brian W Howell

    Published in PLoS ONE (2012-01-01)
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  8. 8

    Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2 by Iqra Nazish, Adamantios Mamais, Anna Mallach, Conceicao Bettencourt, Alice Kaganovich, Thomas Warner, John Hardy, Patrick A. Lewis, Jennifer Pocock, Mark R. Cookson, Rina Bandopadhyay

    Published in Cells (2023-12-01)
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  9. 9

    Divergent Effects of G2019S and R1441C LRRK2 Mutations on LRRK2 and Rab10 Phosphorylations in Mouse Tissues by Lucia Iannotta, Alice Biosa, Jillian H. Kluss, Giulia Tombesi, Alice Kaganovich, Susanna Cogo, Nicoletta Plotegher, Laura Civiero, Evy Lobbestael, Veerle Baekelandt, Mark R. Cookson, Elisa Greggio

    Published in Cells (2020-10-01)
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  10. 10

    Decreased SNCA expression in whole-blood RNA analysis of Parkinson’s disease adjusting for neutrophils by Kayla Y. Xu, Ivo Violich, Elizabeth Hutchins, Eric Alsop, Mike A. Nalls, Anni Moore, Cornelis Blauwendraat, J. Raphael Gibbs, Mark R. Cookson, Kendall Van Keuren-Jensen, David W. Craig

    Published in npj Parkinson's Disease (2025-10-01)
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  11. 11

    Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers. by Laura Civiero, Renée Vancraenenbroeck, Elisa Belluzzi, Alexandra Beilina, Evy Lobbestael, Lauran Reyniers, Fangye Gao, Ivan Micetic, Marc De Maeyer, Luigi Bubacco, Veerle Baekelandt, Mark R Cookson, Elisa Greggio, Jean-Marc Taymans

    Published in PLoS ONE (2012-01-01)
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  12. 12

    LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes by Fumitaka Kawakami, Motoki Imai, Yuki Isaka, Mark R. Cookson, Hiroko Maruyama, Makoto Kubo, Matthew J. Farrer, Makoto Kanzaki, Rei Kawashima, Tatsunori Maekawa, Shun Tamaki, Yoshifumi Kurosaki, Fumiaki Kojima, Kenichi Ohba, Takafumi Ichikawa

    Published in FEBS Open Bio (2023-12-01)
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  13. 13

    A fully automated FAIMS-DIA mass spectrometry-based proteomic pipeline by Luke Reilly, Erika Lara, Daniel Ramos, Ziyi Li, Caroline B. Pantazis, Julia Stadler, Marianita Santiana, Jessica Roberts, Faraz Faghri, Ying Hao, Mike A. Nalls, Priyanka Narayan, Yansheng Liu, Andrew B. Singleton, Mark R. Cookson, Michael E. Ward, Yue A. Qi

    Published in Cell Reports: Methods (2023-10-01)
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  14. 14

    LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease by Maria Kedariti, Emanuele Frattini, Pascale Baden, Susanna Cogo, Laura Civiero, Elena Ziviani, Gianluca Zilio, Federico Bertoli, Massimo Aureli, Alice Kaganovich, Mark R. Cookson, Leonidas Stefanis, Matthew Surface, Michela Deleidi, Alessio Di Fonzo, Roy N. Alcalay, Hardy Rideout, Elisa Greggio, Nicoletta Plotegher

    Published in npj Parkinson's Disease (2022-07-01)
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  15. 15

    Application of Aligned-UMAP to longitudinal biomedical studies by Anant Dadu, Vipul K. Satone, Rachneet Kaur, Mathew J. Koretsky, Hirotaka Iwaki, Yue A. Qi, Daniel M. Ramos, Brian Avants, Jacob Hesterman, Roger Gunn, Mark R. Cookson, Michael E. Ward, Andrew B. Singleton, Roy H. Campbell, Mike A. Nalls, Faraz Faghri

    Published in Patterns (2023-06-01)
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  16. 16

    The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network by Alexandra Beilina, Luis Bonet-Ponce, Ravindran Kumaran, Jennifer J. Kordich, Morié Ishida, Adamantios Mamais, Alice Kaganovich, Sara Saez-Atienzar, David C. Gershlick, Dorien A. Roosen, Laura Pellegrini, Vlad Malkov, Matthew J. Fell, Kirsten Harvey, Juan S. Bonifacino, Darren J. Moore, Mark R. Cookson

    Published in Cell Reports (2020-05-01)
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  17. 17

    Abundant quantitative trait loci exist for DNA methylation and gene expression in human brain. by J Raphael Gibbs, Marcel P van der Brug, Dena G Hernandez, Bryan J Traynor, Michael A Nalls, Shiao-Lin Lai, Sampath Arepalli, Allissa Dillman, Ian P Rafferty, Juan Troncoso, Robert Johnson, H Ronald Zielke, Luigi Ferrucci, Dan L Longo, Mark R Cookson, Andrew B Singleton

    Published in PLoS Genetics (2010-05-01)
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  18. 18

    Triglyceride metabolism controls inflammation and microglial phenotypes associated with APOE4 by Roxan A. Stephenson, Jordy Sepulveda, Kory R. Johnson, Adrian Lita, Jaanam Gopalakrishnan, Dominic J. Acri, Alexandra Beilina, Linling Cheng, Linda G. Yang, Jessica T. Root, Michael E. Ward, Christian Combs, William C. Skarnes, Mark R. Cookson, Han-Yu Shih, Mioara Larion, G. William Rebeck, Priyanka S. Narayan

    Published in Cell Reports (2025-07-01)
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  19. 19

    Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia. by Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson

    Published in PLoS Biology (2021-12-01)
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  20. 20

    Correction: Mutations in LRRK2 linked to Parkinson disease sequester Rab8a to damaged lysosomes and regulate transferrin-mediated iron uptake in microglia. by Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Kirsten Harvey, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson

    Published in PLoS Biology (2022-05-01)
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