Search Results - Michael P Weekes
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Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist by Lior Soday, Yongxu Lu, Jonas D. Albarnaz, Colin T.R. Davies, Robin Antrobus, Geoffrey L. Smith, Michael P. Weekes
Published in Cell Reports (2019-05-01)Get full text
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Haploid genetic screens identify an essential role for PLP2 in the downregulation of novel plasma membrane targets by viral E3 ubiquitin ligases. by Richard T Timms, Lidia M Duncan, Iva A Tchasovnikarova, Robin Antrobus, Duncan L Smith, Gordon Dougan, Michael P Weekes, Paul J Lehner
Published in PLoS Pathogens (2013-01-01)Get full text
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Selective modulation of cell surface proteins during vaccinia infection: A resource for identifying viral immune evasion strategies. by Delphine M Depierreux, Arwen F Altenburg, Lior Soday, Alice Fletcher-Etherington, Robin Antrobus, Brian J Ferguson, Michael P Weekes, Geoffrey L Smith
Published in PLoS Pathogens (2022-06-01)Get full text
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Epstein-Barr virus subverts mevalonate and fatty acid pathways to promote infected B-cell proliferation and survival. by Liang Wei Wang, Zhonghao Wang, Ina Ersing, Luis Nobre, Rui Guo, Sizun Jiang, Stephen Trudeau, Bo Zhao, Michael P Weekes, Benjamin E Gewurz
Published in PLoS Pathogens (2019-09-01)Get full text
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Human Cytomegalovirus Long Non-coding RNA1.2 Suppresses Extracellular Release of the Pro-inflammatory Cytokine IL-6 by Blocking NF-κB Activation by Betty Lau, Karen Kerr, Quan Gu, Katie Nightingale, Robin Antrobus, Nicolás M. Suárez, Richard J. Stanton, Eddie C. Y. Wang, Michael P. Weekes, Andrew J. Davison
Published in Frontiers in Cellular and Infection Microbiology (2020-07-01)Get full text
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Demographic, behavioural and occupational risk factors associated with SARS-CoV-2 infection in UK healthcare workers: a retrospective observational study by Stephen Baker, John Bradley, Mark Ferris, Michael P Weekes, Ashley Shaw, Patrick Maxwell, Shaun Seaman, Daniel James Cooper, Sara Lear, Nyarie Sithole, Hannah Stark, Ian Goodfellow
Published in BMJ Open (2022-11-01)Get full text
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Ubiquitin-Dependent Modification of Skeletal Muscle by the Parasitic Nematode, Trichinella spiralis. by Rhiannon R White, Amy H Ponsford, Michael P Weekes, Rachel B Rodrigues, David B Ascher, Marco Mol, Murray E Selkirk, Steven P Gygi, Christopher M Sanderson, Katerina Artavanis-Tsakonas
Published in PLoS Pathogens (2016-11-01)Get full text
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Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection by Jonas D. Albarnaz, Joanne Kite, Marisa Oliveira, Hanqi Li, Ying Di, Maria H. Christensen, Joao A. Paulo, Robin Antrobus, Steven P. Gygi, Florian I. Schmidt, Edward L. Huttlin, Geoffrey L. Smith, Michael P. Weekes
Published in Nature Communications (2023-12-01)Get full text
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Efficacy of FFP3 respirators for prevention of SARS-CoV-2 infection in healthcare workers by Mark Ferris, Rebecca Ferris, Chris Workman, Eoin O'Connor, David A Enoch, Emma Goldesgeyme, Natalie Quinnell, Parth Patel, Jo Wright, Geraldine Martell, Christine Moody, Ashley Shaw, Christopher JR Illingworth, Nicholas J Matheson, Michael P Weekes
Published in eLife (2021-11-01)Get full text
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Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141. by Jye-Lin Hsu, Dick J H van den Boomen, Peter Tomasec, Michael P Weekes, Robin Antrobus, Richard J Stanton, Eva Ruckova, Daniel Sugrue, Gavin S Wilkie, Andrew J Davison, Gavin W G Wilkinson, Paul J Lehner
Published in PLoS Pathogens (2015-04-01)Get full text
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Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions by Luis V Nobre, Katie Nightingale, Benjamin J Ravenhill, Robin Antrobus, Lior Soday, Jenna Nichols, James A Davies, Sepehr Seirafian, Eddie CY Wang, Andrew J Davison, Gavin WG Wilkinson, Richard J Stanton, Edward L Huttlin, Michael P Weekes
Published in eLife (2019-12-01)Get full text
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Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11 by Benjamin J. Ravenhill, Marisa Oliveira, George Wood, Ying Di, Joanne Kite, Xinyue Wang, Colin T.R. Davies, Yongxu Lu, Robin Antrobus, Gill Elliott, Nerea Irigoyen, David J. Hughes, Paul A. Lyons, Betty Chung, Georg H.H. Borner, Michael P. Weekes
Published in Cell Reports (2025-02-01)Get full text
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Single-dose BNT162b2 vaccine protects against asymptomatic SARS-CoV-2 infection by Nick K Jones, Lucy Rivett, Shaun Seaman, Richard J Samworth, Ben Warne, Chris Workman, Mark Ferris, Jo Wright, Natalie Quinnell, Ashley Shaw, Cambridge COVID-19 Collaboration, Ian G Goodfellow, Paul J Lehner, Rob Howes, Giles Wright, Nicholas J Matheson, Michael P Weekes
Published in eLife (2021-04-01)Get full text
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Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity by Martin Potts, Alice Fletcher-Etherington, Katie Nightingale, Federica Mescia, Laura Bergamaschi, Fernando J. Calero-Nieto, Robin Antrobus, James Williamson, Harriet Parsons, Edward L. Huttlin, Nathalie Kingston, Berthold Göttgens, John R. Bradley, Paul J. Lehner, Nicholas J. Matheson, Kenneth G.C. Smith, Mark R. Wills, Paul A. Lyons, Michael P. Weekes
Published in Cell Reports (2023-06-01)Get full text
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Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation by Ceri A Fielding, Michael P Weekes, Luis V Nobre, Eva Ruckova, Gavin S Wilkie, Joao A Paulo, Chiwen Chang, Nicolás M Suárez, James A Davies, Robin Antrobus, Richard J Stanton, Rebecca J Aicheler, Hester Nichols, Borek Vojtesek, John Trowsdale, Andrew J Davison, Steven P Gygi, Peter Tomasec, Paul J Lehner, Gavin W G Wilkinson
Published in eLife (2017-02-01)Get full text
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Two novel human cytomegalovirus NK cell evasion functions target MICA for lysosomal degradation. by Ceri A Fielding, Rebecca Aicheler, Richard J Stanton, Eddie C Y Wang, Song Han, Sepehr Seirafian, James Davies, Brian P McSharry, Michael P Weekes, P Robin Antrobus, Virginie Prod'homme, Fabien P Blanchet, Daniel Sugrue, Simone Cuff, Dawn Roberts, Andrew J Davison, Paul J Lehner, Gavin W G Wilkinson, Peter Tomasec
Published in PLoS Pathogens (2014-05-01)Get full text
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Screening of healthcare workers for SARS-CoV-2 highlights the role of asymptomatic carriage in COVID-19 transmission by Lucy Rivett, Sushmita Sridhar, Dominic Sparkes, Matthew Routledge, Nick K Jones, Sally Forrest, Jamie Young, Joana Pereira-Dias, William L Hamilton, Mark Ferris, M Estee Torok, Luke Meredith, The CITIID-NIHR COVID-19 BioResource Collaboration, Martin D Curran, Stewart Fuller, Afzal Chaudhry, Ashley Shaw, Richard J Samworth, John R Bradley, Gordon Dougan, Kenneth GC Smith, Paul J Lehner, Nicholas J Matheson, Giles Wright, Ian G Goodfellow, Stephen Baker, Michael P Weekes
Published in eLife (2020-05-01)Get full text
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Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19 by Jun Wang, Prasanti Kotagiri, Paul A. Lyons, Rafia S. Al-Lamki, Federica Mescia, Laura Bergamaschi, Lorinda Turner, Michael D. Morgan, Fernando J. Calero-Nieto, Karsten Bach, Nicole Mende, Nicola K. Wilson, Emily R. Watts, Patrick H. Maxwell, Patrick F. Chinnery, Nathalie Kingston, Sofia Papadia, Kathleen E. Stirrups, Neil Walker, Ravindra K. Gupta, David K. Menon, Kieren Allinson, Sarah J. Aitken, Mark Toshner, Michael P. Weekes, James A. Nathan, Sarah R. Walmsley, Willem H. Ouwehand, Mary Kasanicki, Berthold Göttgens, John C. Marioni, Kenneth G.C. Smith, Jordan S. Pober, John R. Bradley
Published in iScience (2022-03-01)Get full text
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Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections by Christopher JR Illingworth, William L Hamilton, Ben Warne, Matthew Routledge, Ashley Popay, Chris Jackson, Tom Fieldman, Luke W Meredith, Charlotte J Houldcroft, Myra Hosmillo, Aminu S Jahun, Laura G Caller, Sarah L Caddy, Anna Yakovleva, Grant Hall, Fahad A Khokhar, Theresa Feltwell, Malte L Pinckert, Iliana Georgana, Yasmin Chaudhry, Martin D Curran, Surendra Parmar, Dominic Sparkes, Lucy Rivett, Nick K Jones, Sushmita Sridhar, Sally Forrest, Tom Dymond, Kayleigh Grainger, Chris Workman, Mark Ferris, Effrossyni Gkrania-Klotsas, Nicholas M Brown, Michael P Weekes, Stephen Baker, Sharon J Peacock, Ian G Goodfellow, Theodore Gouliouris, Daniela de Angelis, M Estée Török
Published in eLife (2021-08-01)Get full text
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