Search Results - Navdeep S. Chandel
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Targeting fatty acid metabolism in glioblastoma by Jason Miska, Navdeep S. Chandel
Published in The Journal of Clinical Investigation (2023-01-01)Get full text
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Genetic modulation of mitochondrial NAD+ regeneration does not prevent dopaminergic neuron dysfunction caused by mitochondrial complex I impairment by Karis B. D’Alessandro, Enrico Zampese, Jenna L. E. Blum, Britta Kuusik, Alec Palmiotti, Shawn M. Davidson, Colleen R. Reczek, D. James Surmeier, Navdeep S. Chandel, Navdeep S. Chandel, Navdeep S. Chandel
Published in Frontiers in Cell and Developmental Biology (2025-09-01)Get full text
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ApoE enhances mitochondrial metabolism via microRNA-142a/146a-regulated circuits that suppress hematopoiesis and inflammation in hyperlipidemia by Tuan Anh Phu, Ngan K. Vu, Martin Ng, Alex S. Gao, Joshua S. Stoolman, Navdeep S. Chandel, Robert L. Raffai
Published in Cell Reports (2023-10-01)Get full text
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Hif1α-dependent mitochondrial acute O2 sensing and signaling to myocyte Ca2+ channels mediate arterial hypoxic vasodilation by Alejandro Moreno-Domínguez, Olalla Colinas, Ignacio Arias-Mayenco, José M. Cabeza, Juan L. López-Ogayar, Navdeep S. Chandel, Norbert Weissmann, Natascha Sommer, Alberto Pascual, José López-Barneo
Published in Nature Communications (2024-08-01)Get full text
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Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis by William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, GR Scott Budigner, Navdeep S Chandel
Published in eLife (2014-05-01)Get full text
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Treg activation during allograft tolerance induction requires mitochondrion-induced TGF-β1 in type 1 conventional dendritic cells by Samantha L. Schroth, Lei Zhang, Rebecca T.L. Jones, Kristofor Glinton, Nikita L. Mani, Hiroyasu Inui, Jesse T. Davidson, Samuel E. Weinberg, Navdeep S. Chandel, Maria-Luisa Alegre, Edward B. Thorp
Published in The Journal of Clinical Investigation (2025-09-01)Get full text
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Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency. by Lucy Granat, Debbra Y Knorr, Daniel C Ranson, Emma L Hamer, Ram Prosad Chakrabarty, Francesca Mattedi, Laura Fort-Aznar, Frank Hirth, Sean T Sweeney, Alessio Vagnoni, Navdeep S Chandel, Joseph M Bateman
Published in PLoS Genetics (2023-07-01)Get full text
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CD8+ T cells sustain antitumor response by mediating crosstalk between adenosine A2A receptor and glutathione/GPX4 by Siqi Chen, Jie Fan, Ping Xie, Jihae Ahn, Michelle Fernandez, Leah K. Billingham, Jason Miska, Jennifer D. Wu, Derek A. Wainwright, Deyu Fang, Jeffrey A. Sosman, Yong Wan, Yi Zhang, Navdeep S. Chandel, Bin Zhang
Published in The Journal of Clinical Investigation (2024-04-01)Get full text
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Therapeutic targeting of metabolic vulnerabilities in cancers with MLL3/4-COMPASS epigenetic regulator mutations by Zibo Zhao, Kaixiang Cao, Jun Watanabe, Cassandra N. Philips, Jacob M. Zeidner, Yukitomo Ishi, Qixuan Wang, Sarah R. Gold, Katherine Junkins, Elizabeth T. Bartom, Feng Yue, Navdeep S. Chandel, Rintaro Hashizume, Issam Ben-Sahra, Ali Shilatifard
Published in The Journal of Clinical Investigation (2023-07-01)Get full text
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α-Synuclein pathology disrupts mitochondrial function in dopaminergic and cholinergic neurons at-risk in Parkinson’s disease by Fanni F. Geibl, Martin T. Henrich, Zhong Xie, Enrico Zampese, Jun Ueda, Tatiana Tkatch, David L. Wokosin, Elena Nasiri, Constantin A. Grotmann, Valina L. Dawson, Ted M. Dawson, Navdeep S. Chandel, Wolfgang H. Oertel, D. James Surmeier
Published in Molecular Neurodegeneration (2024-10-01)Get full text
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Postischemic inactivation of HIF prolyl hydroxylases in endothelium promotes maladaptive kidney repair by inducing glycolysis by Ratnakar Tiwari, Rajni Sharma, Ganeshkumar Rajendran, Gabriella S. Borkowski, Si Young An, Michael Schonfeld, James O’Sullivan, Matthew J. Schipma, Yalu Zhou, Guillaume Courbon, Benjamin R. Thomson, Valentin David, Susan E. Quaggin, Edward B. Thorp, Navdeep S. Chandel, Pinelopi P. Kapitsinou
Published in The Journal of Clinical Investigation (2025-02-01)Get full text
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Lactate-dependent transcriptional regulation controls mammalian eye morphogenesis by Nozomu Takata, Jason M. Miska, Marc A. Morgan, Priyam Patel, Leah K. Billingham, Neha Joshi, Matthew J. Schipma, Zachary J. Dumar, Nikita R. Joshi, Alexander V. Misharin, Ryan B. Embry, Luciano Fiore, Peng Gao, Lauren P. Diebold, Gregory S. McElroy, Ali Shilatifard, Navdeep S. Chandel, Guillermo Oliver
Published in Nature Communications (2023-07-01)Get full text
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Author Correction: Reduced expression of mitochondrial complex I subunit Ndufs2 does not impact healthspan in mice by Gregory S. McElroy, Ram P. Chakrabarty, Karis B. D’Alessandro, Yuan-Shih Hu, Karthik Vasan, Jerica Tan, Joshua S. Stoolman, Samuel E. Weinberg, Elizabeth M. Steinert, Paul A. Reyfman, Benjamin D. Singer, Warren C. Ladiges, Lin Gao, José Lopéz‑Barneo, Karen Ridge, G. R. Scott Budinger, Navdeep S. Chandel
Published in Scientific Reports (2022-05-01)Get full text
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Inducible CCR2+ nonclassical monocytes mediate the regression of cancer metastasis by Xianpeng Liu, Ziyou Ren, Can Tan, Félix L. Núñez-Santana, Megan E. Kelly, Yuanqing Yan, Haiying Sun, Hiam Abdala-Valencia, Wenbin Yang, Qiang Wu, Takahide Toyoda, Marija Milisav, S. Marina Casalino-Matsuda, Emilia Lecuona, Emily Jeong Cerier, Lena J. Heung, Mohamed E. Abazeed, Harris Perlman, Ruli Gao, Navdeep S. Chandel, G.R. Scott Budinger, Ankit Bharat
Published in The Journal of Clinical Investigation (2024-11-01)Get full text
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Characterization of hyperpolarization-activated cyclic nucleotide-gated channels in oligodendrocytes by Kyle A. Lyman, Ye Han, Andrew P. Robinson, Samuel E. Weinberg, Daniel W. Fisher, Robert J. Heuermann, Reagan E. Lyman, Dong Kyu Kim, Dong Kyu Kim, Dong Kyu Kim, Dong Kyu Kim, Andreas Ludwig, Navdeep S. Chandel, Mark D. Does, Mark D. Does, Mark D. Does, Mark D. Does, Stephen D. Miller, Dane M. Chetkovich
Published in Frontiers in Cellular Neuroscience (2024-02-01)Get full text
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