Search Results - Neil P. King
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Protein identification using Cryo-EM and artificial intelligence guides improved sample purification by Kenneth D. Carr, Dane Evan D. Zambrano, Connor Weidle, Alex Goodson, Helen E. Eisenach, Harley Pyles, Alexis Courbet, Neil P. King, Andrew J. Borst
Published in Journal of Structural Biology: X (2025-06-01)Get full text
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De novo design of protein minibinder agonists of TLR3 by Chloe S. Adams, Hyojin Kim, Abigail E. Burtner, Dong Sun Lee, Craig Dobbins, Cameron Criswell, Brian Coventry, Adri Tran-Pearson, Ho Min Kim, Neil P. King
Published in Nature Communications (2025-01-01)Get full text
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Combinatorial immune refocusing within the influenza hemagglutinin RBD improves cross-neutralizing antibody responses by Annie Dosey, Daniel Ellis, Seyhan Boyoglu-Barnum, Hubza Syeda, Mason Saunders, Michael J. Watson, John C. Kraft, Minh N. Pham, Miklos Guttman, Kelly K. Lee, Masaru Kanekiyo, Neil P. King
Published in Cell Reports (2023-12-01)Get full text
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4
RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera by Cassandra A. L. Simonich, Teagan E. McMahon, Xiaohui Ju, Timothy C. Yu, Natalie Brunette, Terry Stevens-Ayers, Michael J. Boeckh, Neil P. King, Alexander L. Greninger, Jesse D. Bloom
Published in Journal of Virology (2025-07-01)Get full text
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A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines by Jimin Lee, Cameron Stewart, Alexandra Schäfer, Elizabeth M. Leaf, Young-Jun Park, Daniel Asarnow, John M. Powers, Catherine Treichel, Kaitlin R. Sprouse, Davide Corti, Ralph Baric, Neil P. King, David Veesler
Published in Nature Communications (2024-06-01)Get full text
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Fast and versatile sequence-independent protein docking for nanomaterials design using RPXDock. by William Sheffler, Erin C Yang, Quinton Dowling, Yang Hsia, Chelsea N Fries, Jenna Stanislaw, Mark D Langowski, Marisa Brandys, Zhe Li, Rebecca Skotheim, Andrew J Borst, Alena Khmelinskaia, Neil P King, David Baker
Published in PLoS Computational Biology (2023-05-01)Get full text
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Growing Glycans in Rosetta: Accurate de novo glycan modeling, density fitting, and rational sequon design. by Jared Adolf-Bryfogle, Jason W Labonte, John C Kraft, Maxim Shapovalov, Sebastian Raemisch, Thomas Lütteke, Frank DiMaio, Christopher D Bahl, Jesper Pallesen, Neil P King, Jeffrey J Gray, Daniel W Kulp, William R Schief
Published in PLoS Computational Biology (2024-06-01)Get full text
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Protocol and Reagents for Pseudotyping Lentiviral Particles with SARS-CoV-2 Spike Protein for Neutralization Assays by Katharine H. D. Crawford, Rachel Eguia, Adam S. Dingens, Andrea N. Loes, Keara D. Malone, Caitlin R. Wolf, Helen Y. Chu, M. Alejandra Tortorici, David Veesler, Michael Murphy, Deleah Pettie, Neil P. King, Alejandro B. Balazs, Jesse D. Bloom
Published in Viruses (2020-05-01)Get full text
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Deep mutational scanning of H5 hemagglutinin to inform influenza virus surveillance. by Bernadeta Dadonaite, Jenny J Ahn, Jordan T Ort, Jin Yu, Colleen Furey, Annie Dosey, William W Hannon, Amy L Vincent Baker, Richard J Webby, Neil P King, Yan Liu, Scott E Hensley, Thomas P Peacock, Louise H Moncla, Jesse D Bloom
Published in PLoS Biology (2024-11-01)Get full text
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Antigen spacing on protein nanoparticles influences antibody responses to vaccination by Daniel Ellis, Annie Dosey, Seyhan Boyoglu-Barnum, Young-Jun Park, Rebecca Gillespie, Hubza Syeda, Geoffrey B. Hutchinson, Yaroslav Tsybovsky, Michael Murphy, Deleah Pettie, Nick Matheson, Sidney Chan, George Ueda, Jorge A. Fallas, Lauren Carter, Barney S. Graham, David Veesler, Masaru Kanekiyo, Neil P. King
Published in Cell Reports (2023-12-01)Get full text
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Nanoparticle display of prefusion coronavirus spike elicits S1-focused cross-reactive antibody response against diverse coronavirus subgenera by Geoffrey B. Hutchinson, Olubukola M. Abiona, Cynthia T. Ziwawo, Anne P. Werner, Daniel Ellis, Yaroslav Tsybovsky, Sarah R. Leist, Charis Palandjian, Ande West, Ethan J. Fritch, Nianshuang Wang, Daniel Wrapp, Seyhan Boyoglu-Barnum, George Ueda, David Baker, Masaru Kanekiyo, Jason S. McLellan, Ralph S. Baric, Neil P. King, Barney S. Graham, Kizzmekia S. Corbett-Helaire
Published in Nature Communications (2023-10-01)Get full text
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Elicitation of liver-stage immunity by nanoparticle immunogens displaying P. falciparum CSP-derived antigens by Mark D. Langowski, Joseph R. Francica, Alex L. Roederer, Nicholas K. Hurlburt, Justas V. Rodarte, Lais Da Silva Pereira, Barbara J. Flynn, Brian Bonilla, Marlon Dillon, Patience Kiyuka, Rashmi Ravichandran, Connor Weidle, Lauren Carter, Mangala Rao, Gary R. Matyas, Marion Pepper, Azza H. Idris, Robert A. Seder, Marie Pancera, Neil P. King
Published in npj Vaccines (2025-05-01)Get full text
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13
Structural convergence and water-mediated substrate mimicry enable broad neuraminidase inhibition by human antibodies by Julia Lederhofer, Andrew J. Borst, Lam Nguyen, Rebecca A. Gillespie, Connor J. Williams, Emma L. Walker, Julie E. Raab, Christina Yap, Daniel Ellis, Adrian Creanga, Hyon-Xhi Tan, Thi H. T. Do, Michelle Ravichandran, Adrian B. McDermott, Valerie Le Sage, Sarah F. Andrews, Barney S. Graham, Adam K. Wheatley, Douglas S. Reed, Neil P. King, Masaru Kanekiyo
Published in Nature Communications (2025-08-01)Get full text
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14
A gH/gL-encoding replicon vaccine elicits neutralizing antibodies that protect humanized mice against EBV challenge by Kristina R. Edwards, Harman Malhi, Karina Schmidt, Amelia R. Davis, Leah J. Homad, Nikole L. Warner, Crystal B. Chhan, Samuel C. Scharffenberger, Karen Gaffney, Troy Hinkley, Nicole B. Potchen, Jing Yang Wang, Jason Price, M. Juliana McElrath, James Olson, Neil P. King, Jennifer M. Lund, Zoe Moodie, Jesse H. Erasmus, Andrew T. McGuire
Published in npj Vaccines (2024-06-01)Get full text
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Potent neutralization of SARS-CoV-2 variants by RBD nanoparticle and prefusion-stabilized spike immunogens by Marcos C. Miranda, Elizabeth Kepl, Mary Jane Navarro, Chengbo Chen, Max Johnson, Kaitlin R. Sprouse, Cameron Stewart, Anne Palser, Adian Valdez, Deleah Pettie, Claire Sydeman, Cassandra Ogohara, John C. Kraft, Minh Pham, Michael Murphy, Sam Wrenn, Brooke Fiala, Rashmi Ravichandran, Daniel Ellis, Lauren Carter, Davide Corti, Paul Kellam, Kelly Lee, Alexandra C. Walls, David Veesler, Neil P. King
Published in npj Vaccines (2024-10-01)Get full text
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Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles by Philip J. M. Brouwer, Aleksandar Antanasijevic, Marlon de Gast, Joel D. Allen, Tom P. L. Bijl, Anila Yasmeen, Rashmi Ravichandran, Judith A. Burger, Gabriel Ozorowski, Jonathan L. Torres, Celia LaBranche, David C. Montefiori, Rajesh P. Ringe, Marit J. van Gils, John P. Moore, Per Johan Klasse, Max Crispin, Neil P. King, Andrew B. Ward, Rogier W. Sanders
Published in npj Vaccines (2021-02-01)Get full text
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Structural and functional evaluation of de novo-designed, two-component nanoparticle carriers for HIV Env trimer immunogens. by Aleksandar Antanasijevic, George Ueda, Philip J M Brouwer, Jeffrey Copps, Deli Huang, Joel D Allen, Christopher A Cottrell, Anila Yasmeen, Leigh M Sewall, Ilja Bontjer, Thomas J Ketas, Hannah L Turner, Zachary T Berndsen, David C Montefiori, Per Johan Klasse, Max Crispin, David Nemazee, John P Moore, Rogier W Sanders, Neil P King, David Baker, Andrew B Ward
Published in PLoS Pathogens (2020-08-01)Get full text
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Protein nanoparticle vaccines induce potent neutralizing antibody responses against MERS-CoV by Cara W. Chao, Kaitlin R. Sprouse, Marcos C. Miranda, Nicholas J. Catanzaro, Miranda L. Hubbard, Amin Addetia, Cameron Stewart, Jack T. Brown, Annie Dosey, Adian Valdez, Rashmi Ravichandran, Grace G. Hendricks, Maggie Ahlrichs, Craig Dobbins, Alexis Hand, Jackson McGowan, Boston Simmons, Catherine Treichel, Isabelle Willoughby, Alexandra C. Walls, Andrew T. McGuire, Elizabeth M. Leaf, Ralph S. Baric, Alexandra Schäfer, David Veesler, Neil P. King
Published in Cell Reports (2024-12-01)Get full text
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Adjuvanting a subunit SARS-CoV-2 vaccine with clinically relevant adjuvants induces durable protection in mice by Lilit Grigoryan, Audrey Lee, Alexandra C. Walls, Lilin Lai, Benjamin Franco, Prabhu S. Arunachalam, Yupeng Feng, Wei Luo, Abigail Vanderheiden, Katharine Floyd, Samuel Wrenn, Deleah Pettie, Marcos C. Miranda, Elizabeth Kepl, Rashmi Ravichandran, Claire Sydeman, Natalie Brunette, Michael Murphy, Brooke Fiala, Lauren Carter, Robert L. Coffman, David Novack, Harry Kleanthous, Derek T. O’Hagan, Robbert van der Most, Jason S. McLellan, Mehul Suthar, David Veesler, Neil P. King, Bali Pulendran
Published in npj Vaccines (2022-05-01)Get full text
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