Search Results - Pablo Umana

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  1. 1

    Beyond checkpoint inhibition: PD-1 cis-targeting of an IL-2Rβγ-biased interleukin-2 variant as a novel approach to build on checkpoint inhibition by Laura Codarri Deak, Masao Hashimoto, Pablo Umaña, Christian Klein

    Published in OncoImmunology (2023-12-01)
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  2. 2

    Cirugía abierta versus cirugía endovascular en el tratamiento de la patología de la aorta torácica descendente by Mauricio Peláez, José Luis Roa, Félix Montes, Juan Pablo Umaña, Néstor Sandoval, Jaime Camacho Mackenzie

    Published in Revista Universitas Medica (2012-01-01)
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  3. 3

    The tumor-targeted CD40 agonist CEA-CD40 promotes T cell priming via a dual mode of action by increasing antigen delivery to dendritic cells and enhancing their activation by Pedro J Romero, Pablo Umana, Christine Trumpfheller, Eva Sum, Moritz Rapp, Harald Dürr, Alekhya Mazumdar

    Published in Journal for ImmunoTherapy of Cancer (2022-03-01)
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  4. 4

    GA101 P329GLALA, a variant of obinutuzumab with abolished ADCC, ADCP and CDC function but retained cell death induction, is as efficient as rituximab in B-cell depletion and antitu... by Sylvia Herter, Frank Herting, Gunter Muth, Erwin van Puijenbroek, Tilman Schlothauer, Claudia Ferrara, Kevin Brady, Sabine Lang, Marina Bacac, Ekkehard Mössner, Pablo Umana, Christian Klein

    Published in Haematologica (2018-02-01)
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  5. 5

    Heparin-induced DRESS syndrome in a paediatric patient and successful anaesthetic management in cardiovascular bypass surgery: case report by Laura Peña-Blanco, Laura Gutiérrez-Soriano, Félix Ramón Montes, Andrea Barragán-Méndez, Susana Beltrán-Villegas, Juan José López-Reyes, Carlos A. Villa-Hincapié, Juan Pablo Umaña

    Published in Journal of Cardiothoracic Surgery (2024-04-01)
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  6. 6

    863 Novel radioimmunotherapy for lung cancer: a tumor targeting approach by Pedro Romero, Sara Labiano, Christian Klein, Pablo Umana, Tania Wyss, Christine Trumpfheller, Marie-Catherine Vozenin, Céline Godfroid, Jackeline Romero, Vincent Roh, Laura Codarri Deak, Genrich V Tolstonog

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  7. 7

    Pharmacokinetics and Pharmacodynamics of T-Cell Bispecifics in the Tumour Interstitial Fluid by Miro Julian Eigenmann, Tine Veronica Karlsen, Marek Wagner, Olav Tenstad, Tina Weinzierl, Tanja Fauti, Hans Peter Grimm, Trude Skogstrand, Christian Klein, Johannes Sam, Pablo Umana, Marina Bacac, Helge Wiig, Antje-Christine Walz

    Published in Pharmaceutics (2021-12-01)
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  8. 8

    Src/lck inhibitor dasatinib reversibly switches off cytokine release and T cell cytotoxicity following stimulation with T cell bispecific antibodies by Christian Klein, Marina Bacac, Pablo Umana, Gabrielle Leclercq, Hélène Haegel, Anneliese Schneider, Anna Maria Giusti, Estelle Marrer-Berger, Christophe Boetsch, Antje-Christine Walz, Vesna Pulko, Johannes Sam, John Challier, Cristiano Ferlini, Alex Odermatt

    Published in Journal for ImmunoTherapy of Cancer (2021-07-01)
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  9. 9

    Chronic antigen stimulation in melanoma induces T cell exhaustion and limits efficacy of T cell bispecific therapies by Idil Hutter-Karakoc, Eleni Maria Varypataki, Aparna Neelakandhan, Simone Lang, Vesna Kramar, Ahmet Varol, Sasha Simons, Marine Richard, Mudita Pincha, Dario Venetz, Johannes Sam, Nicole Joller, Christian Münz, Pablo Umana, Christian Klein, Maria Amann

    Published in OncoImmunology (2025-12-01)
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  10. 10

    PD-1 cis-targeted IL-2v in combination with radiotherapy inhibits lung cancer growth and remodels the immune microenvironment by Pedro J Romero, Sara Labiano, Gregory Verdeil, Christian Klein, Pablo Umana, Tania Wyss, Christine Trumpfheller, Marie-Catherine Vozenin, Céline Godfroid, Jackeline Romero, Vincent Roh, Genrich V Tolstonog, Chia-Hsien Chuang, Andrea Kelemen, Laura Codarri Deak

    Published in Journal for ImmunoTherapy of Cancer (2025-01-01)
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  11. 11

    T cell margination: investigating the detour of T cells following forimtamig treatment in humanized mice by Nils O’Brien, Joerg P.J. Mueller, Ann-Marie E. Bröske, Jan Attig, Franz Osl, Cylia Crisand, Ann-Katrin Wolf, Richard Rae, Stefanie Lechner, Thomas Pöschinger, Christian Klein, Pablo Umaña, Sara Colombetti, Andreas Beilhack, Jan Eckmann

    Published in mAbs (2025-12-01)
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  12. 12

    Surgical planning aided with 3D technologies for management of complex paracardiac tumors by Camilo E. Pérez-Cualtán, Catalina Vargas-Acevedo, Juliana Sánchez-Posada, Camila Castro-Páez, Roberto Gutiérrez-Vargas, Julián F. Forero-Melo, Juan Manuel Pérez, Juan Carlos Briceño, Héctor M. Medina, Juan Pablo Umaña, Javier Navarro-Rueda, Carlos Eduardo Guerrero-Chalela

    Published in Journal of Cardiothoracic Surgery (2024-09-01)
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  13. 13

    Protease-activation using anti-idiotypic masks enables tumor specificity of a folate receptor 1-T cell bispecific antibody by Martina Geiger, Kay-Gunnar Stubenrauch, Johannes Sam, Wolfgang F. Richter, Gregor Jordan, Jan Eckmann, Carina Hage, Valeria Nicolini, Anne Freimoser-Grundschober, Mirko Ritter, Matthias E. Lauer, Henning Stahlberg, Philippe Ringler, Jigar Patel, Eric Sullivan, Sandra Grau-Richards, Stefan Endres, Sebastian Kobold, Pablo Umaña, Peter Brünker, Christian Klein

    Published in Nature Communications (2020-06-01)
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  14. 14

    4-1BB agonist targeted to fibroblast activation protein α synergizes with radiotherapy to treat murine breast tumor models by Ignacio Melero, Alvaro Teijeira, Christian Klein, Maria E Rodriguez-Ruiz, Christina Claus, Pablo Umana, Tamara Tanos, Carlos E De Andrea, Carlos Luri-Rey, Paloma Sanchez-Mateos, Leticia Fernández-Rubio, María Collantes, Irantzu Serrano-Mendioroz, Celia Barrio-Alonso, Antonio Rullan, Jon Ander Simon, Eneko Garate-Soraluze, Claudia del Pilar Herrero

    Published in Journal for ImmunoTherapy of Cancer (2025-02-01)
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  15. 15

    The physiological interactome of TCR-like antibody therapeutics in human tissues by Estelle Marrer-Berger, Annalisa Nicastri, Angelique Augustin, Vesna Kramar, Hanqing Liao, Lydia Jasmin Hanisch, Alejandro Carpy, Tina Weinzierl, Evelyne Durr, Nathalie Schaub, Ramona Nudischer, Daniela Ortiz-Franyuti, Ekaterina Breous-Nystrom, Janick Stucki, Nina Hobi, Giulia Raggi, Lauriane Cabon, Emmanuelle Lezan, Pablo Umaña, Isaac Woodhouse, Alexander Bujotzek, Christian Klein, Nicola Ternette

    Published in Nature Communications (2024-04-01)
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  16. 16

    Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer by Alfred Zippelius, Petra Herzig, Heinz Läubli, Vaios Karanikas, Gieri Cathomas, Christian Klein, Marta Trüb, Franziska Uhlenbrock, Christina Claus, Martin Thelen, Marina Bacac, Maria Amann, Rosemarie Albrecht, Claudia Ferrara-Koller, Daniela Thommen, Sacha Rothschield, Spasenija Savic Prince, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Abhishek S Kashyap

    Published in Journal for ImmunoTherapy of Cancer (2020-10-01)
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  17. 17

    Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors by Alfred Zippelius, Petra Herzig, Pratiksha Gulati, Christian Klein, Marta Trüb, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Marina Natoli, Klas Hatje, Fabian Junker, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Lothar Tietze, Laura Codarri-Deak, Henry Kao

    Published in Journal for ImmunoTherapy of Cancer (2022-11-01)
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  18. 18

    Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune re... by Anna Spreafico, Eva Muñoz Couselo, Anja Irmisch, Juliana Bessa, George Au-Yeung, Oliver Bechter, Inge Marie Svane, Miguel F. Sanmamed, Miguel F. Sanmamed, Valentina Gambardella, Valentina Gambardella, Meredith McKean, Margaret Callahan, Reinhard Dummer, Christian Klein, Pablo Umaña, Nicole Justies, Florian Heil, Linda Fahrni, Eugenia Opolka-Hoffmann, Inja Waldhauer, Conrad Bleul, Roland F. Staack, Vaios Karanikas, Stephen Fowler

    Published in Frontiers in Oncology (2024-03-01)
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  19. 19

    P1211: TUMOR-ACTIVATED LYMPH NODE FIBROBLASTS SUPPRESS T CELL FUNCTION IN DIFFUSE LARGE B CELL LYMPHOMA by Benedetta Apollonio, Filomena Spada, Nedyalko Petrov, Domenico Cozzetto, Peter Jarvis, Despoina Papazoglou, Shichina Kannambath, Manuela Terranova-Barberio, Rose-Marie Amini, Gunilla Enblad, Charlotte Graham, Reuben Benjamin, Elizabeth H. Phillips, Richard Ellis, Rosamond Nuamah, Mansoor Saqi, Dinis Calado, Richard Rosenquist, Lesley Ann Sutton, Jon Salisbury, Georgios Zacharioudakis, Anna Vardi, Patrick Hagner, Anita Gandhi, Marina Bacac, Christina Claus, Pablo Umana, Ruth Jarrett, Christian Klein, Alexander Deutsch, Alan Ramsay

    Published in HemaSphere (2023-08-01)
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  20. 20

    Tumor-activated lymph node fibroblasts suppress T cell function in diffuse large B cell lymphoma by Benedetta Apollonio, Filomena Spada, Nedyalko Petrov, Domenico Cozzetto, Despoina Papazoglou, Peter Jarvis, Shichina Kannambath, Manuela Terranova-Barberio, Rose-Marie Amini, Gunilla Enblad, Charlotte Graham, Reuben Benjamin, Elisabeth Phillips, Richard Ellis, Rosamond Nuamah, Mansoor Saqi, Dinis P. Calado, Richard Rosenquist, Lesley A. Sutton, Jon Salisbury, Georgios Zacharioudakis, Anna Vardi, Patrick R. Hagner, Anita K. Gandhi, Marina Bacac, Christina Claus, Pablo Umana, Ruth F. Jarrett, Christian Klein, Alexander Deutsch, Alan G. Ramsay

    Published in The Journal of Clinical Investigation (2023-07-01)
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