Search Results - Philippe Merle
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Regorafenib vs. cabozantinib as second-line treatment for advanced hepatocellular carcinoma: an anchored matching-adjusted indirect comparison of efficacy and safety by Philippe Merle, Masatoshi Kudo, Stanimira Krotneva, Kirhan Ozgurdal, Yun Su, Irina Proskorovsky
Published in Liver Cancer (2022-10-01)Get full text
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Case Report: Successful liver transplantation after achieving complete clinical remission of advanced HCC with Atezolizumab plus Bevacizumab combination therapy by Yasmina Chouik, Yasmina Chouik, Domitille Erard, Domitille Erard, Hassan Demian, Thomas Schulz, Tessa Mazard, Kerstin Hartig-Lavie, Teresa Antonini, Jean-Yves Mabrut, Jean-Yves Mabrut, Kayvan Mohkam, Kayvan Mohkam, Agnès Rode, Philippe Merle, Philippe Merle
Published in Frontiers in Immunology (2023-06-01)Get full text
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Copper Isotope Evidence of Oxidative Stress–Induced Hepatic Breakdown and the Transition to Hepatocellular Carcinoma by Philippe Telouk, Marie-Laure Plissonnier, Philippe Merle, Fabien Zoulim, Nadim Fares, Paule Guilloreau, Romain Parent, Justine Bacchetta, Marc Danan, Sergio Carandina, Francis Albarède, PhD
Published in Gastro Hep Advances (2022-01-01)Get full text
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Efficacy and Safety of Atezolizumab Plus Bevacizumab vs Sorafenib in Hepatocellular Carcinoma with Main Trunk and/or Contralateral Portal Vein Invasion in IMbrave150 by Richard S. Finn, Peter R. Galle, Michel Ducreux, Ann-Lii Cheng, Norelle Reilly, Alan Nicholas, Sairy Hernandez, Ning Ma, Philippe Merle, Riad Salem, Daneng Li, Valeriy Breder
Published in Liver Cancer (2024-06-01)Get full text
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Targeted deep sequencing of plasma circulating cell-free DNA reveals Vimentin and Fibulin 1 as potential epigenetic biomarkers for hepatocellular carcinoma. by Reetta Holmila, Athena Sklias, David C Muller, Davide Degli Esposti, Paule Guilloreau, James Mckay, Suleeporn Sangrajrang, Petcharin Srivatanakul, Pierre Hainaut, Philippe Merle, Zdenko Herceg, Andre Nogueira da Costa
Published in PLoS ONE (2017-01-01)Get full text
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Beyond atezolizumab plus bevacizumab in patients with advanced hepatocellular carcinoma: overall efficacy and safety of tyrosine kinase inhibitors in a real-world setting by Manon Falette-Puisieux, Jean-Charles Nault, Mohamed Bouattour, Marie Lequoy, Giuliana Amaddeo, Thomas Decaens, Frederic Di Fiore, Sylvain Manfredi, Philippe Merle, Aurore Baron, Christophe Locher, Anna Pellat, Romain Coriat
Published in Therapeutic Advances in Medical Oncology (2023-08-01)Get full text
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Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma by Anaïs Lopez, Alexia Paturel, Nadim Fares, Floriane Pez, Guanxiong Wang, Patricia Gifu, Lydie Lefrançois, Jihed Chouaref, Pierre Saintigny, Janick Selves, Jean-Marie Peron, Michel Rivoire, Philippe Merle, Claude Caron de Fromentel
Published in PLoS ONE (2025-01-01)Get full text
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Frizzled 7 drives amplification of cancer stem-cell subpopulations and the aggressiveness and poor differentiation of human hepatocellular carcinoma. by Anaïs Lopez, Alexia Paturel, Nadim Fares, Floriane Pez, Guanxiong Wang, Patricia Gifu, Lydie Lefrançois, Jihed Chouaref, Pierre Saintigny, Janick Selves, Jean-Marie Peron, Michel Rivoire, Philippe Merle, Claude Caron de Fromentel
Published in PLoS ONE (2025-01-01)Get full text
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HBV-driven host chromatin accessibility changes affect liver metabolic pathways, iron homeostasis and promote a preneoplastic phenotype by Vincenzo Alfano, Giuseppe Rubens Pascucci, Giacomo Corleone, Massimiliano Cocca, Francesca De Nicola, Océane Floriot, Alexia Paturel, Francesca Casuscelli Di Tocco, Claude Caron de Fromentel, Philippe Merle, Michel Rivoire, Massimo Levrero, Francesca Guerrieri
Published in Journal of Experimental & Clinical Cancer Research (2025-05-01)Get full text
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Evaluation of postoperative ascites after somatostatin infusion following hepatectomy for hepatocellular carcinoma by laparotomy: a multicenter randomized double-blind controlled t... by Kayvan Mohkam, Michel Rayar, Jean-Philippe Adam, Fabrice Muscari, Agnès Rode, Philippe Merle, Pierre Pradat, Stéphanie Bauler, Isabelle Delfour, Laurence Chiche, Christian Ducerf, Karim Boudjema, Mickaël Lesurtel, Christophe Laurent, Jean-Yves Mabrut
Published in BMC Cancer (2018-08-01)Get full text
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362 Association of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio with clinical outcomes to tislelizumab monotherapy in patients with previously treated advanced h... by Yong Liu, Richard Hubner, Ruiqi Huang, Yee Chao, Ying Cheng, Zhirong Shen, Xikun Wu, Congying Xie, Bai Li, Chen Ling, Philippe MERLE, Jane Margetts, Helena Verdaguer Mata, Cong Fei, Sandra Chica Duque, Zhenggang Ren
Published in Journal for ImmunoTherapy of Cancer (2021-11-01)Article -
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Comparative Efficacy of Atezolizumab plus Bevacizumab and Other Treatment Options for Patients with Unresectable Hepatocellular Carcinoma: A Network Meta-Analysis by Arndt Vogel, Lorenza Rimassa, Hui-Chan Sun, Ghassan K. Abou-Alfa, Anthony El-Khoueiry, David J. Pinato, Javier Sanchez Alvarez, Monica Daigl, Panos Orfanos, Michael Leibfried, Marie-Hélène Blanchet Zumofen, Vincent E. Gaillard, Philippe Merle
Published in Liver Cancer (2021-05-01)Get full text
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Outcomes Based on Plasma Biomarkers for the Phase 3 CELESTIAL Trial of Cabozantinib versus Placebo in Advanced Hepatocellular Carcinoma by Lorenza Rimassa, Robin Kate Kelley, Tim Meyer, Baek-Yeol Ryoo, Philippe Merle, Joong-Won Park, Jean-Frederic Blanc, Ho Yeong Lim, Albert Tran, Yi-Wah Chan, Paul McAdam, Evelyn Wang, Ann-Lii Cheng, Anthony B. El-Khoueiry, Ghassan K. Abou-Alfa
Published in Liver Cancer (2021-12-01)Get full text
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Effect of pembrolizumab on viral hepatitis load and transaminases in advanced hepatocellular carcinoma by Stephen Lam Chan, Richard S. Finn, Julien Edeline, Sadahisa Ogasawara, Jennifer J. Knox, Bruno Daniele, Baek-Yeol Ryoo, Philippe Merle, Mohamed Bouattour, Ho-Yeong Lim, Yee Chao, Thomas Yau, Barbara Anne Haber, Usha Malhotra, Abby B. Siegel, Chih-Chin Liu, Masatoshi Kudo, Ann-Lii Cheng
Published in Annals of Hepatology (2026-01-01)Get full text
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Second-line pembrolizumab for advanced HCC: Meta-analysis of the phase III KEYNOTE-240 and KEYNOTE-394 studies by Richard S. Finn, Kangsheng Gu, Xi Chen, Philippe Merle, Kyung-Hun Lee, Mohamed Bouattour, Peiguo Cao, Wei Wang, Ann-Lii Cheng, Liangjun Zhu, Ho Yeong Lim, Masatoshi Kudo, Yueyin Pan, Ting-Tsung Chang, Julien Edeline, Wei Li, Ping Yang, Chen Li, Jianfeng Li, Abby B. Siegel, Shukui Qin
Published in JHEP Reports (2025-06-01)Get full text
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Pembrolizumab as Second-Line Therapy for Advanced Hepatocellular Carcinoma: Longer-Term Follow-Up From the Phase 3 KEYNOTE-240 Trial by Philippe Merle, Masatoshi Kudo, Julien Edeline, Mohamed Bouattour, Ann-Lii Cheng, Stephen Lam Chan, Thomas Yau, Marcelo Garrido, Jennifer Knox, Bruno Daniele, Valeriy Breder, Ho Yeong Lim, Sadahisa Ogasawara, Stéphane Cattan, Yee Chao, Abby B. Siegel, Iván Martinez-Forero, Ziwen Wei, Chih-Chin Liu, Richard S. Finn
Published in Liver Cancer (2023-02-01)Get full text
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TACE and conformal radiotherapy vs. TACE alone for hepatocellular carcinoma: A randomised controlled trial by Cyrille Féray, Loic Campion, Philippe Mathurin, Isabelle Archambreaud, Xavier Mirabel, Jean Pierre Bronowicki, Emmanuel Rio, Christophe Perret, Laurent Mineur, Frédéric Oberti, Yann Touchefeu, Jérôme Gournay, Hélène Regnault, Julien Edeline, Agnès Rode, Patrick Hillion, Jean Frédéric Blanc, Eric Nguyen Khac, Daniel Azoulay, Alain Luciani, Athena Galetto Preglisasco, Elodie Faurel-Paul, Hélène Auble, Françoise Mornex, Philippe Merle
Published in JHEP Reports (2023-04-01)Get full text
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Diagnostic value of the wnt target and cancer-associated blood biomarker hPG80: ONCOPRO case-control prospective study by Benoit You, Sebastien Couraud, Philippe Ceruse, Lionel Badet, Philippe Paparel, Alice Durand, Marielle Guillet, Philippe Merle, Gaelle Lescuyer, Charles-André Philip, Francois Ducray, Mathieu Pioche, Lionel Karlin, Jean-Christophe Lifante, Olivier Glehen, Pierre-Adrien Bolze, Marion Chauvenet, Carole Langlois-Jacques, Fabien Subtil, Marie Piecyk, Aurore Carrot, Dominique Joubert, Alexandre Prieur, Berengere Vire, Sara Calattini, Lea Payen
Published in Biomarker Research (2025-07-01)Get full text
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Tislelizumab in Patients with Previously Treated Advanced Hepatocellular Carcinoma (RATIONALE-208): A Multicenter, Non-Randomized, Open-Label, Phase 2 Trial by Zhenggang Ren, Michel Ducreux, Ghassan K. Abou-Alfa, Philippe Merle, Weijia Fang, Julien Edeline, Zhiwei Li, Lihua Wu, Eric Assenat, Sheng Hu, Lorenza Rimassa, Tao Zhang, Jean-Frédéric Blanc, Hongming Pan, Paul Ross, Chia-Jui Yen, Albert Tran, Guoliang Shao, Mohamed Bouattour, Yajin Chen, Tim Meyer, Jinlin Hou, David Tougeron, Yuxian Bai, Ming-Mo Hou, Zhiqiang Meng, John Wu, Vincent Li, Sandra Chica-Duque, Ann-Lii Cheng
Published in Liver Cancer (2022-10-01)Get full text
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Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic you... by Narcisse Patrice Komas, Sumantra Ghosh, Mariama Abdou-Chekaraou, Pierre Pradat, Nasser Al Hawajri, Alexandre Manirakiza, Gina Laure Laghoe, Claudine Bekondi, Ségolène Brichler, Jean-Omer Ouavéné, Abdoulaye Sépou, Brice Martial Yambiyo, Jean Chrysostome Gody, Valentin Fikouma, Athénais Gerber, Natali Abeywickrama Samarakoon, Dulce Alfaiate, Caroline Scholtès, Nora Martel, Frédéric Le Gal, Hugo Lo Pinto, Ikram Amri, Olivier Hantz, David Durantel, Jean-Louis Lesbordes, Emmanuel Gordien, Philippe Merle, Tudor Drugan, Christian Trépo, Fabien Zoulim, Jean-Claude Cortay, Alan Campbell Kay, Paul Dény
Published in PLoS Neglected Tropical Diseases (2018-04-01)Get full text
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