Search Results - Raphael Mechoulam
Raphael Mechoulam
Raphael Mechoulam, }} (; 5 November 1930 – 9 March 2023) was a Bulgarian-born Israeli organic chemist and a professor in the Department of Natural Materials at the School of Pharmacy in the Faculty of Medicine of the Hebrew University of Jerusalem. Mechoulam served as Rector of the university from 1979–1982. He was elected to the Israel Academy of Sciences and Humanities in 1994 and served as its scientific chair from 2007-2013. He was a recipient of the Israel Prize for Chemistry Research in 2000 and the Harvey Prize for 2019-2020.Known as "the godfather of cannabis research", Mechoulam is best known for his work (together with Y. Gaoni) in the isolation of tetrahydrocannabinol, or THC, the main active principle of cannabis. He was also successful in the isolation and identification of the endogenous cannabinoids anandamide from the brain and 2-arachidonoyl glycerol, or 2-AG, from peripheral organs. His work has led to the discovery of the endocannabinoid system, which has effects on many important aspects of human health. Provided by Wikipedia
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Cannabinoid Quinones—A Review and Novel Observations by Natalya M. Kogan, Maximilian Peters, Raphael Mechoulam
Published in Molecules (2021-03-01)Get full text
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Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: Relevance to Parkinson's disease by Isabel Lastres-Becker, Francisco Molina-Holgado, José A. Ramos, Raphael Mechoulam, Javier Fernández-Ruiz
Published in Neurobiology of Disease (2005-06-01)Get full text
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The endocannabinoid 2-AG protects the blood–brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines by David Panikashvili, Na'ama A. Shein, Raphael Mechoulam, Victoria Trembovler, Ron Kohen, Alexander Alexandrovich, Esther Shohami
Published in Neurobiology of Disease (2006-05-01)Get full text
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N-oleoyl glycine and N-oleoyl alanine attenuate alcohol self-administration and preference in mice by Samah Shahen-Zoabi, Reem Smoum, Alexey Bingor, Etty Grad, Alina Nemirovski, Tawfeeq Shekh-Ahmad, Raphael Mechoulam, Rami Yaka
Published in Translational Psychiatry (2023-07-01)Get full text
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Fenchone Derivatives as a Novel Class of CB2 Selective Ligands: Design, Synthesis, X-ray Structure and Therapeutic Potential by Reem Smoum, Christeene Haj, Shira Hirsch, Alina Nemirovski, Zhannah Yekhtin, Benny Bogoslavsky, Gaganjyot Kaur Bakshi, Mukesh Chourasia, Ruth Gallily, Joseph Tam, Raphael Mechoulam
Published in Molecules (2022-02-01)Get full text
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Novel CBG Derivatives Can Reduce Inflammation, Pain and Obesity by Natalya M. Kogan, Yarden Lavi, Louise M. Topping, Richard. O. Williams, Fiona E. McCann, Zhanna Yekhtin, Marc Feldmann, Ruth Gallily, Raphael Mechoulam
Published in Molecules (2021-09-01)Get full text
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Anti-Tumorigenic Effect of a Novel Derivative of 2-Hydroxyoleic Acid and the Endocannabinoid Anandamide on Neuroblastoma Cells by Hana Golan, Raphael Mechoulam, Reem Smoum, Efrat Cohen-Zada, Sara Pri-Chen, Sapir Wiener, Igor Grinberg, Dekel D. Bar-Lev, Christeeneh G. Haj, Tamar Fisher, Amos Toren
Published in Biomedicines (2022-06-01)Get full text
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Endocannabinoid basis of personality—Insights from animal model of social behavior by Natalya M. Kogan, Natalya M. Kogan, Natalya M. Kogan, Dilorom Begmatova, Liudmila Vinnikova, Sergey Malitsky, Maxim Itkin, Eyal Sharon, Artem Klinov, Jonathan Gorelick, Igor Koman, Igor Koman, Zvi Vogel, Raphael Mechoulam, Albert Pinhasov, Albert Pinhasov
Published in Frontiers in Pharmacology (2023-08-01)Get full text
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